Success Metrics

Clinical Success Rate
63.6%

Based on 7 completed trials

Completion Rate
64%(7/11)
Active Trials
55(74%)
Results Posted
86%(6 trials)
Terminated
4(5%)

Phase Distribution

Ph phase_2
45
61%
Ph phase_3
10
14%
Ph early_phase_1
1
1%
Ph phase_1
17
23%

Phase Distribution

18

Early Stage

45

Mid Stage

10

Late Stage

Phase Distribution73 total trials
Early Phase 1First-in-human
1(1.4%)
Phase 1Safety & dosage
17(23.3%)
Phase 2Efficacy & side effects
45(61.6%)
Phase 3Large-scale testing
10(13.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

58.3%

7 of 12 finished

Non-Completion Rate

41.7%

5 ended early

Currently Active

55

trials recruiting

Total Trials

74

all time

Status Distribution
Active(62)
Completed(7)
Terminated(5)

Detailed Status

Recruiting36
Active, not recruiting19
Completed7
Not yet recruiting7
Terminated4
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
74
Active
55
Success Rate
63.6%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.4%)
Phase 117 (23.3%)
Phase 245 (61.6%)
Phase 310 (13.7%)

Trials by Status

completed79%
recruiting3649%
withdrawn11%
not_yet_recruiting79%
terminated45%
active_not_recruiting1926%

Recent Activity

Clinical Trials (74)

Showing 20 of 74 trialsScroll for more
NCT05601440Phase 2

Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer

Recruiting
NCT06524544Phase 3

A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitean-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer

Recruiting
NCT04647916Phase 2

Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases

Active Not Recruiting
NCT07178730Phase 3

NeoAdjuvant Therapy Comparing Sacituzumab Govitecan+Pembrolizumab vs. SoC Chemotherapy in Clinical Stage II-III, Triple-negative Early Breast Cancer

Not Yet Recruiting
NCT04826341Phase 1

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

Active Not Recruiting
NCT04434040Phase 2

Atezolizumab + Sacituzumab Govitecan to Prevent Recurrence in TNBC (ASPRIA)

Recruiting
NCT05143229Phase 1

Alpelisib And Sacituzumab Govitecan For Treatment Of Breast Cancer

Active Not Recruiting
NCT04579224Phase 3

Comparing the New Anti-cancer Drug Eribulin With Chemotherapy Against the Usual Chemotherapy Alone in Metastatic Urothelial Cancer

Active Not Recruiting
NCT06431633Phase 3

Study of Treatment With Sacituzumab and Zimberelimab for Patients With Lung Cancer Confined to the Chest and Previously Operated on Who Were Not Disease-free.

Recruiting
NCT04468061Phase 2

Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

Recruiting
NCT07328490Phase 1

Bispecific T-Cell Engager Tarlatamab and TROP2 Targeted Antibody Drug Conjugate Sacituzumab Govitecan in Previously Treated Extensive-Stage Small Cell Lung Cancer and Extrapulmonary Neuroendocrine Cancer

Withdrawn
NCT03606967Phase 2

Testing the Addition of an Individualized Vaccine to Durvalumab and Tremelimumab and Chemotherapy in Patients With Metastatic Triple Negative Breast Cancer

Recruiting
NCT05581589Phase 2

Sacituzumab Govitecan Before Radical Cystectomy for the Treatment of Non-Urothelial Muscle Invasive Bladder Cancer

Terminated
NCT05327530Phase 2

A Study of the Safety and Efficacy of Various Combinations of Avelumab as Therapy in Locally Advanced or Metastatic Urothelial Carcinoma (JAVELIN Bladder Medley)

Active Not Recruiting
NCT06161532Phase 2

Sacituzumab Govitecan With or Without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) Such as High Grade Neuroendocrine Carcinomas, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile C...

Recruiting
NCT07339059Phase 2

Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer

Recruiting
NCT04595565Phase 3

Sacituzumab Govitecan in Primary HER2-negative Breast Cancer

Active Not Recruiting
NCT03971409Phase 2

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

Active Not Recruiting
NCT07011654Phase 1

Study of Naxitamab and Sacituzumab Govitecan in Patients With Metastatic Triple-negative Breast Cancer (TNBC)

Recruiting
NCT06311214Phase 2

Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
74