Success Metrics

Clinical Success Rate
68.5%

Based on 85 completed trials

Completion Rate
69%(85/124)
Active Trials
97(36%)
Results Posted
100%(85 trials)
Terminated
39(15%)

Phase Distribution

Ph phase_2
113
42%
Ph phase_1
94
35%
Ph phase_4
10
4%
Ph not_applicable
1
0%
Ph phase_3
29
11%
Ph early_phase_1
2
1%

Phase Distribution

96

Early Stage

113

Mid Stage

39

Late Stage

Phase Distribution249 total trials
Early Phase 1First-in-human
2(0.8%)
Phase 1Safety & dosage
94(37.8%)
Phase 2Efficacy & side effects
113(45.4%)
Phase 3Large-scale testing
29(11.6%)
Phase 4Post-market surveillance
10(4.0%)
N/ANon-phased studies
1(0.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

64.4%

85 of 132 finished

Non-Completion Rate

35.6%

47 ended early

Currently Active

97

trials recruiting

Total Trials

266

all time

Status Distribution
Active(108)
Completed(85)
Terminated(47)
Other(26)

Detailed Status

Completed85
Recruiting68
Terminated39
Active, not recruiting29
unknown25
Not yet recruiting11

Development Timeline

Analytics

Development Status

Total Trials
266
Active
97
Success Rate
68.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.8%)
Phase 194 (37.8%)
Phase 2113 (45.4%)
Phase 329 (11.6%)
Phase 410 (4.0%)
N/A1 (0.4%)

Trials by Status

completed8532%
terminated3915%
unknown259%
not_yet_recruiting114%
suspended10%
active_not_recruiting2911%
recruiting6826%
withdrawn83%

Recent Activity

Clinical Trials (266)

Showing 20 of 266 trialsScroll for more
NCT06973668Phase 2

A Randomized Study to Compare Post-transplant Cyclophosphamide, Sirolimus, Ruxolitinib and Post-transplant Cyclophosphamide, Sirolimus, Mycophenolate Mofetil to Prevent Graft Versus Host Disease

Recruiting
NCT07357727Phase 3

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

Recruiting
NCT07356245Phase 2

Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma

Recruiting
NCT07032727Phase 2

Olutasidenib Combined With Co-targeted Therapy in Relapsed or Refractory IDH1-mutated Myeloid Malignancies Harboring Activated Signaling Pathway Mutations

Recruiting
NCT04176198Phase 1

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

Recruiting
NCT06150157Phase 1

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Recruiting
NCT04384692Phase 2

Peritransplant Ruxolitinib for Patients With Primary and Secondary Myelofibrosis

Active Not Recruiting
NCT06616155Phase 1

Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer

Recruiting
NCT06120140Phase 2

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

Recruiting
NCT06160791Phase 2

Ruxolitinib With De-Intensified HLH-94 for the Treatment of Hemophagocytic Lymphohistiocytosis (HLH)

Recruiting
NCT02928978Phase 2

Ruxolitinib for Premalignant Breast Disease

Completed
NCT03069326Phase 2

A Clinical Study to Test the Effects of Ruxolitinib And Thalidomide Combination for Patients With Myelofibrosis

Active Not Recruiting
NCT03017820Phase 1

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

Recruiting
NCT04562389Phase 3

Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis

Active Not Recruiting
NCT07521046Phase 1

Tolerability of Ropeginterferon Alfa-2b Add-on to Ongoing Ruxolitinib Therapy in Myelofibrosis (RopeRux in Myelofibrosis)

Not Yet Recruiting
NCT07498205Phase 4

Comparing Momelotinib and Ruxolitinib in People With Untreated Myelofibrosis and Low Blood Cell Counts

Not Yet Recruiting
NCT05010005Phase 1

A Study of Ruxolitinib and Duvelisib in People With Lymphoma

Recruiting
NCT06008808Phase 1

Ruxolitinib With and Without CTLA-4 Ig Abatacept for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation

Recruiting
NCT06660355Phase 2

Ruxolitinib vs Prednisone as First-line Therapy for cGVHD Needing Systemic Therapy

Recruiting
NCT05088356Phase 1

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
266