Success Metrics

Clinical Success Rate
68.0%

Based on 85 completed trials

Completion Rate
68%(85/125)
Active Trials
102(38%)
Results Posted
104%(88 trials)
Terminated
40(15%)

Phase Distribution

Ph phase_1
98
36%
Ph phase_2
114
42%
Ph phase_3
30
11%
Ph early_phase_1
2
1%
Ph phase_4
10
4%
Ph not_applicable
1
0%

Phase Distribution

100

Early Stage

114

Mid Stage

40

Late Stage

Phase Distribution255 total trials
Early Phase 1First-in-human
2(0.8%)
Phase 1Safety & dosage
98(38.4%)
Phase 2Efficacy & side effects
114(44.7%)
Phase 3Large-scale testing
30(11.8%)
Phase 4Post-market surveillance
10(3.9%)
N/ANon-phased studies
1(0.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

63.9%

85 of 133 finished

Non-Completion Rate

36.1%

48 ended early

Currently Active

102

trials recruiting

Total Trials

272

all time

Status Distribution
Active(114)
Completed(85)
Terminated(48)
Other(25)

Detailed Status

Completed85
Recruiting69
Terminated40
Active, not recruiting33
unknown25
Not yet recruiting12

Development Timeline

Analytics

Development Status

Total Trials
272
Active
102
Success Rate
68.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (0.8%)
Phase 198 (38.4%)
Phase 2114 (44.7%)
Phase 330 (11.8%)
Phase 410 (3.9%)
N/A1 (0.4%)

Trials by Status

not_yet_recruiting124%
recruiting6925%
terminated4015%
withdrawn83%
active_not_recruiting3312%
completed8531%
unknown259%

Recent Activity

Clinical Trials (272)

Showing 20 of 272 trialsScroll for more
NCT06079879Phase 3

A Study of Bomedemstat (IMG-7289/MK-3543) Compared to Best Available Therapy (BAT) in Participants With Essential Thrombocythemia and an Inadequate Response or Intolerance of Hydroxyurea (MK-3543-006)

Recruiting
NCT03681561Phase 1

Nivolumab With Ruxolitinib in Relapsed or Refractory Classical Hodgkin Lymphoma

Recruiting
NCT05548062

Study to Identify and Describe Predictive Factors for Thromboembolic Events in Patients With High-risk Polycythemia Vera

Active Not Recruiting
NCT07643025Phase 2

Belumosudil With Ruxolitnib as Second Line Therapy for Chronic Graft Versus Host Disease (cGvHD) After Steroid Failure

Not Yet Recruiting
NCT07357727Phase 3

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

Recruiting
NCT07340138Phase 1

Study of Pelabresib add-on to Ruxolitinib in Japanese Adult Patients With Myelofibrosis

Recruiting
NCT03017820Phase 1

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

Recruiting
NCT06508463Phase 1

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

Recruiting
NCT06824103Phase 4

Study of Efficacy and Safety of Ruxolitinib in Chinese Participants With Corticosteroid-refractory Chronic Graft vs. Host Disease

Recruiting
NCT06120140Phase 2

Enhanced Dermatological Care to Reduce Rash and Paronychia in Epidermal Growth Factor Receptor (EGRF)-Mutated Non-Small Cell Lung Cancer (NSCLC) Treated First-line With Amivantamab Plus Lazertinib

Active Not Recruiting
NCT06150157Phase 1

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

Recruiting
NCT03514069Phase 1

Ruxolitinib With Radiation and Temozolomide for Grade III Gliomas and Glioblastoma

Completed
NCT07252050Phase 1

Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease

Recruiting
NCT02158858Phase 1

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

Completed
NCT07588139Phase 1

A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants

Recruiting
NCT07352566Phase 4

Utilization of a Microdevice for Psoriasis and Atopic Dermatitis

Not Yet Recruiting
NCT05998408Phase 1

JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure

Active Not Recruiting
NCT06536166Phase 2

Ruxolitinib Treatment in Inclusion Body Myositis

Recruiting
NCT02386800Phase 4

CINC424A2X01B Rollover Protocol

Active Not Recruiting
NCT07359859Phase 2

A Study of Ruxolitinib for Preventing Graft-Versus-Host Disease in People With a Hematologic Malignancy Who Will Receive a Stem Cell Transplant

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
272