Success Metrics

Clinical Success Rate
77.6%

Based on 800 completed trials

Completion Rate
78%(800/1031)
Active Trials
339(21%)
Results Posted
73%(582 trials)
Terminated
231(14%)

Phase Distribution

Ph phase_3
289
18%
Ph not_applicable
40
2%
Ph phase_4
49
3%
Ph phase_1
397
25%
Ph phase_2
786
49%
Ph early_phase_1
15
1%

Phase Distribution

412

Early Stage

786

Mid Stage

338

Late Stage

Phase Distribution1576 total trials
Early Phase 1First-in-human
15(1.0%)
Phase 1Safety & dosage
397(25.2%)
Phase 2Efficacy & side effects
786(49.9%)
Phase 3Large-scale testing
289(18.3%)
Phase 4Post-market surveillance
49(3.1%)
N/ANon-phased studies
40(2.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.1%

800 of 1109 finished

Non-Completion Rate

27.9%

309 ended early

Currently Active

339

trials recruiting

Total Trials

1,618

all time

Status Distribution
Active(368)
Completed(800)
Terminated(309)
Other(141)

Detailed Status

Completed800
Terminated231
Recruiting197
Active, not recruiting142
unknown137
Withdrawn78

Development Timeline

Analytics

Development Status

Total Trials
1618
Active
339
Success Rate
77.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 115 (1.0%)
Phase 1397 (25.2%)
Phase 2786 (49.9%)
Phase 3289 (18.3%)
Phase 449 (3.1%)
N/A40 (2.5%)

Trials by Status

suspended40%
withdrawn785%
unknown1378%
enrolling_by_invitation30%
active_not_recruiting1429%
completed80049%
terminated23114%
recruiting19712%
not_yet_recruiting262%

Recent Activity

Clinical Trials (1,618)

Showing 20 of 1,618 trialsScroll for more
NCT05376319Phase 2

PR3-AAV Resilient Remission or PRRR

Terminated
NCT03920722Phase 3

Efficacy and Safety of Rituximab in the Treatment of Good Prognosis Microscopic Polyangiitis

Completed
NCT06149286Phase 3

A Trial to Find Out if Odronextamab Combined With Lenalidomide is Safe and Works Better Than Rituximab Combined With Lenalidomide in Adult Participants With Follicular Lymphoma and Marginal Zone Lymphoma

Recruiting
NCT01829958Not Applicable

Comprehensive Geriatric Assessment to Predict Toxic Events in Older Patients With Non-Hodgkin Lymphoma With Imbedded Pilot Study of Pre-Phase Therapy

Active Not Recruiting
NCT06717347Phase 3

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Recruiting
NCT05283720Phase 2

A Study to Evaluate Adverse Events and Change in Disease Activity of Subcutaneous (SC) Epcoritamab in Combination With Oral and Intravenous Anti-Neoplastic Agents in Adult Participants With Non-Hodgkin Lymphoma

Recruiting
NCT03474744Phase 2

Copanlisib and Rituximab in Marginal Zone Lymphoma Patients

Active Not Recruiting
NCT06191744Phase 3

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma

Recruiting
NCT04872790Phase 1

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

Active Not Recruiting
NCT06045247Phase 2

Phase 2 Trial of Epcoritamab in Combination With Rituximab-mini CVP for Older Unfit/Frail Patients or Anthracycline-Ineligible Adult Patients With Newly Diagnosed Diffuse Large B-cell Lymphoma

Recruiting
NCT05952024Phase 2

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

Recruiting
NCT05139017Phase 2

A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)

Recruiting
NCT04712097Phase 3

A Study Evaluating the Efficacy and Safety of Mosunetuzumab in Combination With Lenalidomide in Comparison to Rituximab in Combination With Lenalidomide With a US Extension of Mosunetuzumab in Combination With Lenalidomide in Participants With Follicular Lymphoma

Active Not Recruiting
NCT05848765Phase 2

Relapsed Follicular Lymphoma Randomised Trial Against Standard ChemoTherapy

Recruiting
NCT06337318Phase 3

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Recruiting
NCT03267433Phase 3

Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

Active Not Recruiting
NCT06890884Phase 2

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Recruiting
NCT02727803Phase 2

Personalized NK Cell Therapy in CBT

Recruiting
NCT04115631Phase 2

A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma

Active Not Recruiting
NCT01318317Phase 1

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
1,618