Success Metrics

Clinical Success Rate
66.7%

Based on 6 completed trials

Completion Rate
67%(6/9)
Active Trials
3(21%)
Results Posted
117%(7 trials)
Terminated
3(21%)

Phase Distribution

Ph phase_2
6
43%
Ph early_phase_1
1
7%
Ph phase_1
7
50%

Phase Distribution

8

Early Stage

6

Mid Stage

0

Late Stage

Phase Distribution14 total trials
Early Phase 1First-in-human
1(7.1%)
Phase 1Safety & dosage
7(50.0%)
Phase 2Efficacy & side effects
6(42.9%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

60.0%

6 of 10 finished

Non-Completion Rate

40.0%

4 ended early

Currently Active

3

trials recruiting

Total Trials

14

all time

Status Distribution
Active(3)
Completed(6)
Terminated(4)
Other(1)

Detailed Status

Completed6
Terminated3
Active, not recruiting2
Suspended1
Recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
14
Active
3
Success Rate
66.7%
Most Advanced
Phase 2

Trials by Phase

Early Phase 11 (7.1%)
Phase 17 (50.0%)
Phase 26 (42.9%)

Trials by Status

completed643%
suspended17%
recruiting17%
withdrawn17%
terminated321%
active_not_recruiting214%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT03899987Phase 2

Aspirin and Rintatolimod With or Without Interferon-alpha 2b in Treating Patients With Prostate Cancer Before Surgery

Active Not Recruiting
NCT04093323Phase 2

Polarized Dendritic Cell (aDC1) Based Treatment, Interferon Alpha-2, Rintatolimod, and Celecoxib for the Treatment of HLA-A2+ Refractory Melanoma

Terminated
NCT03734692Phase 1

Systemic Immune Checkpoint Blockade and Intraperitoneal Chemo-Immunotherapy in Recurrent Ovarian Cancer

Active Not Recruiting
NCT04379518Phase 1

Rintatolimod and IFN Alpha-2b for the Treatment of COVID-19 in Cancer Patients

Terminated
NCT05494697Phase 2

Ampligen Combined With SOC Versus SOC Alone Following First-Line Therapy in Subjects With LAPC

Suspended
NCT05756166Phase 1

Rintatolimod, Celecoxib and Interferon Alpha 2b With Pembrolizumab For the Treatment of Patients With Metastatic or Unresectable Triple Negative Breast Cancer

Terminated
NCT05927142Phase 1

Combining Anti-PD-L1 Immune Checkpoint Inhibitor Durvalumab With TLR-3 Agonist Rintatolimod in Patients With Metastatic Pancreatic Ductal Adenocarcinoma for Therapy Efficacy

Recruiting
NCT05592418Phase 2

Study to Evaluate the Efficacy and Safety of Ampligen in Patients With Post-COVID Conditions

Completed
NCT04081389Phase 1

Chemokine Modulation Therapy and Standard Chemotherapy Before Surgery for the Treatment of Early Stage Triple Negative Breast Cancer

Completed
NCT03599453Early Phase 1

Chemokine Modulation Therapy and Pembrolizumab in Treating Participants With Metastatic Triple-Negative Breast Cancer

Completed
NCT03403634Phase 2

Celecoxib, Recombinant Interferon Alfa-2b, and Rintatolimod in Treating Patients With Colorectal Cancer Metastatic to the Liver

Completed
NCT04119830Phase 2

Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer

Withdrawn
NCT02151448Phase 1

αDC1 Vaccine + Chemokine Modulatory Regimen (CKM) as Adjuvant Treatment of Peritoneal Surface Malignancies

Completed
NCT01355393Phase 1

Vaccine Therapy in Combination With Rintatolimod and/or Sargramostim in Treating Patients With Stage II-IV HER2-Positive Breast Cancer

Completed

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14