Success Metrics

Clinical Success Rate
100.0%

Based on 15 completed trials

Completion Rate
100%(15/15)
Active Trials
1(5%)
Results Posted
60%(9 trials)

Phase Distribution

Ph phase_4
3
14%
Ph phase_3
3
14%
Ph not_applicable
1
5%
Ph phase_1
5
23%
Ph phase_2
7
32%

Phase Distribution

5

Early Stage

7

Mid Stage

6

Late Stage

Phase Distribution19 total trials
Phase 1Safety & dosage
5(26.3%)
Phase 2Efficacy & side effects
7(36.8%)
Phase 3Large-scale testing
3(15.8%)
Phase 4Post-market surveillance
3(15.8%)
N/ANon-phased studies
1(5.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

88.2%

15 of 17 finished

Non-Completion Rate

11.8%

2 ended early

Currently Active

1

trials recruiting

Total Trials

22

all time

Status Distribution
Active(1)
Completed(15)
Terminated(2)
Other(4)

Detailed Status

Completed15
unknown4
Withdrawn2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
22
Active
1
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (26.3%)
Phase 27 (36.8%)
Phase 33 (15.8%)
Phase 43 (15.8%)
N/A1 (5.3%)

Trials by Status

withdrawn29%
unknown418%
active_not_recruiting15%
completed1568%

Recent Activity

Clinical Trials (22)

Showing 20 of 22 trialsScroll for more
NCT02494986Phase 2

A Roll-over Study With Rilpivirine for Human Immunodeficiency Virus Type 1 (HIV-1) Infected Participants Who Participated in Rilpivirine Pediatric Studies

Active Not Recruiting
NCT00042289

Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy

Completed
NCT03194165

Population Pharmacokinetics of Antiretroviral in Children

Completed
NCT02470650Phase 4

Cost-effectiveness of Different Antiretroviral Treatment in Patients HIV Naive

Withdrawn
NCT04012931Phase 2

A Study of Switching to RPV Plus Other ARVs in HIV-1-infected Children (Aged 2 to <12 Years) Who Are Virologically Suppressed

Completed
NCT03127189Phase 1

A Study to Investigate the Effect of Different Particle Sizes on the Single-dose Pharmacokinetics of Rilpivirine After Intramuscular Injection of a Long-acting Nanosuspension in Healthy Participants

Completed
NCT00799864Phase 2

A Study to Evaluate the Pharmacokinetics, Safety, Tolerability, and Antiviral Activity of Rilpivirine (TMC278) in Human Immunodeficiency Virus Infected Adolescents and Children Aged Greater Than or Equal to 6 Years

Completed
NCT03782142

Effect on HIV Medications on EPC Cells

Completed
NCT01975012Phase 1

Safety, Tolerability, Drug Interactions, and Antiviral Activity of Rilpivirine in Antiretroviral-Naive HIV-Infected Children Less Than 12 Years of Age

Withdrawn
NCT01266902Phase 3

A Trial With TMC278-TIDP6-C222 for Continued TMC278 Access in Patients Infected With Human Immunodeficiency Virus-1

Completed
NCT01709084Phase 3

A Clinical Trial Comparing the Efficacy of Tenofovir Disoproxil Fumarate/Emtricitabine/Rilpivirine (TDF/FTC/RPV) Versus TDF/FTC/Efavirenz (TDF/FTC/EFV) in Patients With Undetectable Plasma HIV-1 RNA on Current First-line Treatment

Completed
NCT03589040Phase 2

Darunavir and Rilpivirine Interactions With Etonogestrel Contraceptive Implant

Unknown
NCT03589027Phase 2

Darunavir and Rilpivirine Interactions With Levonorgestrel Implant

Unknown
NCT03664440Not Applicable

Efficacy of Rilpivirine-based Regimens as Switch Therapy From Nevirapine-based Regimens in HIV-infected Patients

Completed
NCT02165202Phase 2

Phase II Safety and Acceptability of an Investigational Injectable Product, TMC278LA, for Pre-Exposure Prophylaxis

Completed
NCT00855335Phase 3

A Single-arm, Open-label, Study to Assess the Pharmacokinetics of Darunavir and Ritonavir, Darunavir and Cobicistat, Etravirine, and Rilpivirine in HIV-1 Infected Pregnant Women

Completed
NCT03033368Phase 2

Rilpivirine in Virologically Suppressed Adolescents

Unknown
NCT01585038Phase 4

Efavirenz Versus Rilpivirine on Vascular Function, Inflammation, and Oxidative Stress

Completed
NCT02404233Phase 4

Open Label, Pilot Study of Darunavir Boosted by Cobicistat in Combination With Rilpivirine to Treat HIV+ Naïve Subjects

Unknown
NCT01562886Phase 1

The Rilpivirine Cerebrospinal-fluid (CSF) Study

Completed

Drug Details

Intervention Type
DRUG
Total Trials
22