Success Metrics

Clinical Success Rate
77.1%

Based on 54 completed trials

Completion Rate
77%(54/70)
Active Trials
6(5%)
Results Posted
56%(30 trials)
Terminated
16(14%)

Phase Distribution

Ph phase_1
9
8%
Ph not_applicable
26
23%
Ph phase_3
24
21%
Ph phase_4
24
21%
Ph early_phase_1
3
3%
Ph phase_2
25
22%

Phase Distribution

12

Early Stage

25

Mid Stage

48

Late Stage

Phase Distribution111 total trials
Early Phase 1First-in-human
3(2.7%)
Phase 1Safety & dosage
9(8.1%)
Phase 2Efficacy & side effects
25(22.5%)
Phase 3Large-scale testing
24(21.6%)
Phase 4Post-market surveillance
24(21.6%)
N/ANon-phased studies
26(23.4%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

68.4%

54 of 79 finished

Non-Completion Rate

31.6%

25 ended early

Currently Active

6

trials recruiting

Total Trials

113

all time

Status Distribution
Active(9)
Completed(54)
Terminated(25)
Other(25)

Detailed Status

Completed54
unknown24
Terminated16
Withdrawn9
Recruiting5
Not yet recruiting3

Development Timeline

Analytics

Development Status

Total Trials
113
Active
6
Success Rate
77.1%
Most Advanced
Phase 4

Trials by Phase

Early Phase 13 (2.7%)
Phase 19 (8.1%)
Phase 225 (22.5%)
Phase 324 (21.6%)
Phase 424 (21.6%)
N/A26 (23.4%)

Trials by Status

active_not_recruiting11%
unknown2421%
completed5448%
not_yet_recruiting33%
suspended11%
terminated1614%
recruiting54%
withdrawn98%

Recent Activity

Clinical Trials (113)

Showing 20 of 113 trialsScroll for more
NCT02016196Phase 3

Rifaximin vs Placebo for the Prevention of Encephalopathy in Patients Treated by TIPS

Completed
NCT07209371Phase 2

Rifaximin Versus No Intervention for the Treatment of IgA Monoclonal Gammopathy of Undetermined Significance

Recruiting
NCT03729271Phase 4

Hydrogen Breath Test an Instrument to Predict Rifaximin-Response in Irritable Bowel Syndrome Predominant Diarrhea

Completed
NCT04244877Phase 3

Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility

Withdrawn
NCT04254549Phase 2

Rifaximin in Patients With Diabetic Gastroparesis

Terminated
NCT07203846Phase 4

Modulation of Gut MicroFLORA With Rifaximin to Reduce High Platelet Reactivity in Post-ACS Patients on Ticagrelor

Not Yet Recruiting
NCT04249622Phase 2

Rifaximin for the Treatment of Gastrointestinal Toxicities Related to Pertuzumab-Based Therapy in Patients With Stage I-III HER2 Positive Breast Cancer

Terminated
NCT03575195Phase 1

Microbiota Intervention to Change the Response of Parkinson's Disease

Suspended
NCT06483737Not Applicable

Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE)

Recruiting
NCT03820817Phase 1

Rifaximin in Patients With Monoclonal Gammopathy

Active Not Recruiting
NCT03069131Phase 3

Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascites

Completed
NCT06808009Not Applicable

Goal Directed Ammonia Lowering Therapy in Hyperammonemic ACLF Patients With no Overt HE to Reduce Major Adverse Liver Related Outcomes (GOAL Trial)

Not Yet Recruiting
NCT05587036Phase 2

Effects of Rifaximin on Gut Microbiota and Emotion

Recruiting
NCT06652087Not Applicable

Rifaximin and Cardiac Function in Patients with Heart Failure with Preserved Ejection Fraction

Recruiting
NCT06630572Phase 4

Rifaximin in Cirrhosis: Effects on Endotoxin and Haemostatic Indexes

Terminated
NCT06518850Phase 1

Study of Clinical Features and Efficacy of Small Intestinal Bacterial Overgrowth in Patients With Abdominal Distension

Not Yet Recruiting
NCT01345175Phase 3

Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer

Completed
NCT05150587Phase 2

Safety, Efficacy and Pharmacokinetics of Rifaximin in Patients With Moderate-to-severe Papulopustular Rosacea

Completed
NCT02470780Phase 2

Treating Bacterial Overgrowth in Parkinson's Disease

Completed
NCT04910815Not Applicable

Feasibility of a New Diagnostic Device to Assess Small Intestinal Dysbiosis in Routine Clinical Setting.

Unknown

Drug Details

Intervention Type
DRUG
Total Trials
113