Success Metrics

Clinical Success Rate
93.2%

Based on 41 completed trials

Completion Rate
93%(41/44)
Active Trials
4(7%)
Results Posted
27%(11 trials)
Terminated
3(6%)

Phase Distribution

Ph phase_3
7
13%
Ph phase_4
5
9%
Ph phase_1
19
35%
Ph phase_2
12
22%
Ph not_applicable
8
15%

Phase Distribution

19

Early Stage

12

Mid Stage

12

Late Stage

Phase Distribution51 total trials
Phase 1Safety & dosage
19(37.3%)
Phase 2Efficacy & side effects
12(23.5%)
Phase 3Large-scale testing
7(13.7%)
Phase 4Post-market surveillance
5(9.8%)
N/ANon-phased studies
8(15.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

93.2%

41 of 44 finished

Non-Completion Rate

6.8%

3 ended early

Currently Active

4

trials recruiting

Total Trials

54

all time

Status Distribution
Active(6)
Completed(41)
Terminated(3)
Other(4)

Detailed Status

Completed41
unknown4
Recruiting3
Terminated3
Not yet recruiting2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
54
Active
4
Success Rate
93.2%
Most Advanced
Phase 4

Trials by Phase

Phase 119 (37.3%)
Phase 212 (23.5%)
Phase 37 (13.7%)
Phase 45 (9.8%)
N/A8 (15.7%)

Trials by Status

active_not_recruiting12%
unknown47%
not_yet_recruiting24%
recruiting36%
terminated36%
completed4176%

Recent Activity

Clinical Trials (54)

Showing 20 of 54 trialsScroll for more
NCT07514364Phase 4

The Effect of Rifabutin in Mycobacterium Abscessus With Inducible Clarithromycin Resistance

Recruiting
NCT04310930Phase 2

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

Recruiting
NCT04630145Phase 2

A Study of Bedaquiline Administered as Part of a Treatment Regimen With Clarithromycin and Ethambutol in Adult Patients With Treatment-refractory Mycobacterium Avium Complex-lung Disease (MAC-LD)

Completed
NCT07485010Phase 2

Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial

Not Yet Recruiting
NCT07066722Phase 1

A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults

Completed
NCT07199452Phase 1

A Study of Rifabutin and MK-4646 in Healthy Participants (MK-4646-004)

Completed
NCT05766267Phase 2

Short-course Regimens for the Treatment of Pulmonary Tuberculosis

Active Not Recruiting
NCT05874544Phase 4

Rescue Therapy for Helicobacter Pylori Infection

Completed
NCT06731023

Efficacy of a 14-Day Bismuth-Containing Quadruple Therapy Guided by Drug Susceptibility Testing in Patients with Extremely Refractory Helicobacter Pylori Infection: an Exploratory Study

Not Yet Recruiting
NCT05458102Phase 1

Drug-Drug Interaction Study of Vesatolimod in Adults With HIV-1 Who Have Very Low or Undetectable Virus Levels

Terminated
NCT04470908Phase 1

The Effect of Moderate CYP3A Inducer Rifabutin on the Pharmacokinetics of Zanubrutinib in Healthy Males

Completed
NCT03891901Phase 2

A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin

Completed
NCT02256696Phase 2

Assessing PA-824 for Tuberculosis (the APT Trial)

Completed
NCT04672525Phase 3

Rifabutin Versus Rifampicin for Treatment of Staphylococcal PJI Treated With DAIR

Recruiting
NCT03709355Phase 1

Pharmacokinetics Study to Evaluate Drug-Drug Interactions and Safety of Elpida® in Co-Administration With Other Drugs

Completed
NCT00001047Phase 3

Study of Four Different Treatment Approaches for Patients Who Have Mycobacterium Avium Complex Disease (MAC) Plus AIDS

Completed
NCT00001058Phase 2

A Comparison of Three Drug Combinations Containing Clarithromycin in the Treatment of Mycobacterium Avium Complex (MAC) Disease in Patients With AIDS

Completed
NCT00001030Phase 3

The Safety and Effectiveness of Clarithromycin and Rifabutin Used Alone or in Combination to Prevent Mycobacterium Avium Complex (MAC) or Disseminated MAC Disease in HIV-Infected Patients

Completed
NCT00000826Phase 1

Effect of Fluconazole, Clarithromycin, and Rifabutin on the Pharmacokinetics of Sulfamethoxazole-Trimethoprim and Dapsone and Their Hydroxylamine Metabolites

Completed
NCT00000877Phase 1

Study of How Indinavir (an Anti-HIV Drug) and Rifabutin (a Drug Used to Treat MAC, an HIV-Associated Disease) Interact in HIV-Positive and HIV-Negative Adults

Completed

Drug Details

Intervention Type
DRUG
Total Trials
54