Success Metrics

Clinical Success Rate
93.3%

Based on 14 completed trials

Completion Rate
93%(14/15)
Active Trials
4(20%)
Results Posted
64%(9 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_2
2
10%
Ph not_applicable
1
5%
Ph phase_3
2
10%
Ph phase_1
15
75%

Phase Distribution

15

Early Stage

2

Mid Stage

2

Late Stage

Phase Distribution20 total trials
Phase 1Safety & dosage
15(75.0%)
Phase 2Efficacy & side effects
2(10.0%)
Phase 3Large-scale testing
2(10.0%)
N/ANon-phased studies
1(5.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

93.3%

14 of 15 finished

Non-Completion Rate

6.7%

1 ended early

Currently Active

4

trials recruiting

Total Trials

20

all time

Status Distribution
Active(4)
Completed(14)
Terminated(1)
Other(1)

Detailed Status

Completed14
Recruiting2
Active, not recruiting2
Terminated1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
20
Active
4
Success Rate
93.3%
Most Advanced
Phase 3

Trials by Phase

Phase 115 (75.0%)
Phase 22 (10.0%)
Phase 32 (10.0%)
N/A1 (5.0%)

Trials by Status

completed1470%
recruiting210%
active_not_recruiting210%
terminated15%
unknown15%

Recent Activity

Clinical Trials (20)

Showing 20 of 20 trials
NCT06310551Phase 1

First Time in Human Study of Long Acting VH4524184 Formulations

Recruiting
NCT05996471Phase 2

A Study to Investigate the Virologic Efficacy and Safety of VH3810109 + Cabotegravir Compared to Standard of Care (SOC) in Male and Female Adults Living With Human Immunodeficiency Virus (HIV)

Active Not Recruiting
NCT05418868Phase 1

A Study to Investigate Pharmacokinetics, Safety and Tolerability of Long-Acting Cabotegravir Plus Recombinant Human Hyaluronidase PH20 in Healthy Adult Participants

Recruiting
NCT03735121Phase 3

A Study to Investigate Atezolizumab Subcutaneous in Patients With Previously Treated Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Completed
NCT03656718Phase 1

A Study of Subcutaneous Nivolumab Monotherapy With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)

Completed
NCT03446040Phase 1

An Investigational Immunotherapy Study of BMS-986258 Alone and in Combination With Nivolumab in Participants With Solid Cancers That Are Advanced or Have Spread

Terminated
NCT05625399Phase 3

A Study of Subcutaneous Nivolumab + Relatlimab Fixed-dose Combination (FDC) in Previously Untreated Metastatic or Unresectable Melanoma

Active Not Recruiting
NCT03972306Phase 1

A Study To Investigate The Pharmacokinetics, Safety, And Tolerability Of Subcutaneous Ocrelizumab Administration In Participants With Multiple Sclerosis

Completed
NCT03320707Phase 1

A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of JNJ-54767414 (Daratumumab) in Healthy Participants

Completed
NCT05291520Phase 1

A Study to Investigate the Safety and Pharmacokinetics of a Single Dose of VH3810109 (Also Known as GSK3810109), Administered Either Subcutaneously (SC) With rHuPH20 or Intravenously (IV), in Healthy Adult Participants

Completed
NCT03538626Phase 1

Phase I, Open-Label, Dose-Escalation Study of a Human Monoclonal Antibody, VRC-HIVMAB091-00-AB (N6LS), Administered Intravenously or Subcutaneously With or Without Recombinant Human Hyaluronidase PH20 (rHuPH20)

Completed
NCT05396742Phase 1

Pharmacokinetic Study of Ravulizumab Administered Subcutaneously With Recombinant Human Hyaluronidase PH20 (rHuPH20) in Healthy Adult Volunteers

Completed
NCT04112498Phase 1

A Phase 1, Bioavailability Study of Relatlimab in Combination With Nivolumab

Completed
NCT02754141Phase 1

An Investigational Immuno-therapy Study of Experimental Medication BMS-986179 Given Alone and in Combination With Nivolumab

Completed
NCT04920370Phase 1

Study of Subcutaneous and Intravenous ALXN1720 With and Without rHuPH20 in Healthy Subjects

Completed
NCT00928447Phase 2

Study of the Intradermal Injection of rHuPH20 or Placebo in Participants With Nickel Allergic Contact Dermatitis

Completed
NCT00803972Phase 1

Dose-Ranging, Pharmacokinetic (PK), Glucodynamic (GD), Safety and Tolerability Study of Subcutaneously (SC) Administered Humulin R and Humalog With or Without rHuPH20

Completed
NCT00807963Phase 1

Pharmacokinetic, Safety and Tolerability Study of SC Administered Bisphosphonate With rHuPH20 vs Bisphosphonate Alone

Completed
NCT02885259Not Applicable

HyQvia in Multifocal Motor Neuropathy

Unknown
NCT00862849Phase 1

Pharmacokinetic and Glucodynamic Crossover Study of Subcutaneously (SC) Administered Insulin Lispro + Recombinant Human Hyaluronidase (rHuPH20) and Regular Human Insulin + rHuPH20 Compared to Insulin Lispro Alone

Completed

All 20 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
20