Success Metrics

Clinical Success Rate
100.0%

Based on 3 completed trials

Completion Rate
100%(3/3)
Active Trials
12(60%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_3
2
10%
Ph phase_2
3
15%
Ph phase_1
14
70%

Phase Distribution

14

Early Stage

3

Mid Stage

2

Late Stage

Phase Distribution19 total trials
Phase 1Safety & dosage
14(73.7%)
Phase 2Efficacy & side effects
3(15.8%)
Phase 3Large-scale testing
2(10.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

75.0%

3 of 4 finished

Non-Completion Rate

25.0%

1 ended early

Currently Active

12

trials recruiting

Total Trials

20

all time

Status Distribution
Active(15)
Completed(3)
Terminated(1)
Other(1)

Detailed Status

Recruiting11
Completed3
Not yet recruiting3
Active, not recruiting1
unknown1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
20
Active
12
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 114 (73.7%)
Phase 23 (15.8%)
Phase 32 (10.5%)

Trials by Status

active_not_recruiting15%
completed315%
not_yet_recruiting315%
recruiting1155%
unknown15%
withdrawn15%

Recent Activity

Clinical Trials (20)

Showing 20 of 20 trials
NCT07283640Phase 1

A Phase IB Trial of Subcutaneous Blinatumomab in Combination With Revumenib for Patients With KMT2A-rearranged Acute Lymphoblastic Leukemia

Not Yet Recruiting
NCT07498465Phase 1

A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia

Withdrawn
NCT06177067Phase 1

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
NCT07563010Phase 2

Menin-Inhibitor Targeted Maintenance in AML

Not Yet Recruiting
NCT07211958Phase 3

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

Recruiting
NCT05761171Phase 2

A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Active Not Recruiting
NCT05886049Phase 1

Testing the Addition of an Anti-cancer Drug, SNDX-5613, to the Standard Chemotherapy Treatment (Daunorubicin and Cytarabine) for Newly Diagnosed Patients With Acute Myeloid Leukemia That Has Changes in NPM1 or MLL/KMT2A Gene

Recruiting
NCT07052994Phase 1

A Phase Ia/Ib Trial of Revumenib Combined With Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin (GO) in Frontline and Relapsed /Refractory Pediatric Acute Leukemia Patients

Not Yet Recruiting
NCT06284486Phase 1

A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib

Recruiting
NCT06313437Phase 1

Revumenib in Combination With 7+3 + Midostaurin in AML

Recruiting
NCT04065399Phase 1

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Recruiting
NCT06222580Phase 1

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

Recruiting
NCT06575296Phase 1

Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant

Recruiting
NCT06229912Phase 2

A Phase II Study of the Menin Inhibitor Revumenib in Leukemia Associated With Upregulation of HOX Genes

Recruiting
NCT05731947Phase 1

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

Completed
NCT07356154Phase 1

A Study of Revumenib and Mezigdomide in People With Leukemia

Recruiting
NCT05918913

Expanded Access Program for Revumenib

Unknown
NCT06652438Phase 3

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

Recruiting
NCT05406817Phase 1

Study of Radiolabeled Revumenib in Adults With Acute Leukemia

Completed
NCT05326516Phase 1

A Study of Revumenib in Combination With Chemotherapy in Participants With R/R Acute Leukemia

Completed

All 20 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
20