Success Metrics

Clinical Success Rate
66.7%

Based on 2 completed trials

Completion Rate
67%(2/3)
Active Trials
12(50%)
Results Posted
50%(1 trials)
Terminated
1(4%)

Phase Distribution

Ph phase_3
2
8%
Ph phase_2
6
25%
Ph phase_1
15
63%

Phase Distribution

15

Early Stage

6

Mid Stage

2

Late Stage

Phase Distribution23 total trials
Phase 1Safety & dosage
15(65.2%)
Phase 2Efficacy & side effects
6(26.1%)
Phase 3Large-scale testing
2(8.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

40.0%

2 of 5 finished

Non-Completion Rate

60.0%

3 ended early

Currently Active

12

trials recruiting

Total Trials

24

all time

Status Distribution
Active(18)
Completed(2)
Terminated(3)
Other(1)

Detailed Status

Recruiting11
Not yet recruiting6
Withdrawn2
Completed2
Active, not recruiting1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
24
Active
12
Success Rate
66.7%
Most Advanced
Phase 3

Trials by Phase

Phase 115 (65.2%)
Phase 26 (26.1%)
Phase 32 (8.7%)

Trials by Status

not_yet_recruiting625%
active_not_recruiting14%
withdrawn28%
recruiting1146%
completed28%
terminated14%
unknown14%

Recent Activity

Clinical Trials (24)

Showing 20 of 24 trialsScroll for more
NCT06652438Phase 3

Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML

Recruiting
NCT06177067Phase 1

Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting
NCT07734077Phase 1

Revumenib in Patients With Myelofibrosis

Not Yet Recruiting
NCT07211958Phase 3

Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation

Recruiting
NCT07686107Phase 2

Trial of Revumenib Plus FLA Chemotherapy for Children With Relapsed or Refractory NUP98-rearranged AML."

Not Yet Recruiting
NCT05886049Phase 1

A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

Recruiting
NCT05761171Phase 2

A Study of Revumenib in Combination With Chemotherapy for Patients Diagnosed With Relapsed or Refractory Leukemia

Active Not Recruiting
NCT05731947Phase 1

Evaluation of Revumenib in Participants With Colorectal Cancer and Other Solid Tumors

Terminated
NCT07605949Phase 2

Revumenib, Azacitidine, and VENetoclax in Newly Diagnosed KMT2A-Rearranged AML

Not Yet Recruiting
NCT07283640Phase 1

A Phase IB Trial of Subcutaneous Blinatumomab in Combination With Revumenib for Patients With KMT2A-rearranged Acute Lymphoblastic Leukemia

Not Yet Recruiting
NCT07563010Phase 2

Menin-Inhibitor Targeted Maintenance in AML

Not Yet Recruiting
NCT07356154Phase 1

A Study of Revumenib and Mezigdomide in People With Leukemia

Recruiting
NCT07636564Phase 2

Testing Blinatumomab With or Without Revumenib in Patients With B-cell Acute Lymphoblastic Leukemia With a Genetic Change Requiring More Treatment

Not Yet Recruiting
NCT07052994Phase 1

A Phase Ia/Ib Trial of Revumenib Combined With Cytarabine, Daunorubicin, and Gemtuzumab Ozogamicin (GO) in Frontline and Relapsed /Refractory Pediatric Acute Leukemia Patients

Withdrawn
NCT06222580Phase 1

SNDX-5613 and Gilteritinib for the Treatment of Relapsed or Refractory FLT3-Mutated Acute Myeloid Leukemia and Concurrent MLL-Rearrangement or NPM1 Mutation

Recruiting
NCT07498465Phase 1

A Study to Find the Highest Dose of SNDX-5613 (Revumenib) as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, and Mixed Phenotype Acute Leukemia

Withdrawn
NCT06284486Phase 1

A Multi-Site Break Through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib

Recruiting
NCT06313437Phase 1

Revumenib in Combination With 7+3 + Midostaurin in AML

Recruiting
NCT04065399Phase 1

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

Recruiting
NCT06575296Phase 1

Revumenib for the Treatment of Acute Leukemia in Patients Post-Allogeneic Stem Cell Transplant

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
24