Success Metrics

Clinical Success Rate
69.6%

Based on 16 completed trials

Completion Rate
70%(16/23)
Active Trials
25(45%)
Results Posted
94%(15 trials)
Terminated
7(13%)

Phase Distribution

Ph phase_3
4
7%
Ph early_phase_1
1
2%
Ph phase_2
24
44%
Ph phase_1
25
45%

Phase Distribution

26

Early Stage

24

Mid Stage

4

Late Stage

Phase Distribution54 total trials
Early Phase 1First-in-human
1(1.9%)
Phase 1Safety & dosage
25(46.3%)
Phase 2Efficacy & side effects
24(44.4%)
Phase 3Large-scale testing
4(7.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

57.1%

16 of 28 finished

Non-Completion Rate

42.9%

12 ended early

Currently Active

25

trials recruiting

Total Trials

55

all time

Status Distribution
Active(26)
Completed(16)
Terminated(12)
Other(1)

Detailed Status

Recruiting17
Completed16
Active, not recruiting8
Terminated7
Withdrawn5
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
55
Active
25
Success Rate
69.6%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.9%)
Phase 125 (46.3%)
Phase 224 (44.4%)
Phase 34 (7.4%)

Trials by Status

not_yet_recruiting12%
terminated713%
withdrawn59%
unknown12%
completed1629%
recruiting1731%
active_not_recruiting815%

Recent Activity

Clinical Trials (55)

Showing 20 of 55 trialsScroll for more
NCT06959537Phase 1

A Phase Ib Study of Novel Combination (New) of Low Dose Oral CyclophoSphamide (s) to Potentiate Axatilimab (A) + Retifanlimab (R) in Treating Metastatic Triple Negative Breast Cancer (TNBC)

Recruiting
NCT06179160Phase 1

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Recruiting
NCT06149481Phase 1

Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

Recruiting
NCT06320405Phase 1

Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors

Recruiting
NCT04205812Phase 3

Platinum-Based Chemotherapy With/Without INCMGA00012, an Anti-PD-1 Antibody, in Non-Small Cell Lung Cancer

Completed
NCT07677579Phase 2

NIMBLE-CRC: NeoImmunoModulation Before Leveraging Excision in Colorectal Rectal Cancer

Not Yet Recruiting
NCT07425054Phase 2

ctHPVDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Locally-Advanced Anal Cancer

Recruiting
NCT07468136Phase 1

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Recruiting
NCT05455697Phase 1

Tafasitamab, Retifanlimab, and Rituximab in Combination With Standard Therapy for the Treatment of Diffuse Large B-cell Lymphoma

Active Not Recruiting
NCT06873789Phase 1

A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors

Active Not Recruiting
NCT04463771Phase 2

Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy.

Completed
NCT04374305Phase 2

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

Recruiting
NCT05743595Phase 1

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Active Not Recruiting
NCT06610682Early Phase 1

A Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-altered Glioma

Recruiting
NCT04577014Phase 1

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

Recruiting
NCT06072612Phase 3

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

Recruiting
NCT03328026Phase 1

Combination Study of SV-BR-1-GM With Retifanlimab

Completed
NCT05287113Phase 2

Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Active Not Recruiting
NCT04387084Phase 1

Short-term Fasting Prior to PD-1/PD-L1 Inhibitor Therapy for of Advanced or Metastatic Skin Malignancy

Active Not Recruiting
NCT05345002Phase 2

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
55