Success Metrics

Clinical Success Rate
68.2%

Based on 15 completed trials

Completion Rate
68%(15/22)
Active Trials
24(44%)
Results Posted
100%(15 trials)
Terminated
7(13%)

Phase Distribution

Ph phase_1
25
46%
Ph phase_2
23
43%
Ph phase_3
4
7%
Ph early_phase_1
1
2%

Phase Distribution

26

Early Stage

23

Mid Stage

4

Late Stage

Phase Distribution53 total trials
Early Phase 1First-in-human
1(1.9%)
Phase 1Safety & dosage
25(47.2%)
Phase 2Efficacy & side effects
23(43.4%)
Phase 3Large-scale testing
4(7.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

55.6%

15 of 27 finished

Non-Completion Rate

44.4%

12 ended early

Currently Active

24

trials recruiting

Total Trials

54

all time

Status Distribution
Active(26)
Completed(15)
Terminated(12)
Other(1)

Detailed Status

Recruiting16
Completed15
Active, not recruiting8
Terminated7
Withdrawn5
Not yet recruiting2

Development Timeline

Analytics

Development Status

Total Trials
54
Active
24
Success Rate
68.2%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (1.9%)
Phase 125 (47.2%)
Phase 223 (43.4%)
Phase 34 (7.5%)

Trials by Status

unknown12%
terminated713%
withdrawn59%
not_yet_recruiting24%
active_not_recruiting815%
completed1528%
recruiting1630%

Recent Activity

Clinical Trials (54)

Showing 20 of 54 trialsScroll for more
NCT07425054Phase 2

ctHPVDNA Response-Adapted Chemoradiation +/- Retifanlimab Treatment in Locally-Advanced Anal Cancer

Not Yet Recruiting
NCT04463771Phase 2

Safety and Efficacy of Retifanlimab (INCMGA00012) Alone or in Combination With Other Therapies in Participants With Advanced or Metastatic Endometrial Cancer Who Have Progressed on or After Platinum-based Chemotherapy.

Completed
NCT06149481Phase 1

Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC)

Recruiting
NCT06959537Phase 1

A Phase Ib Study of Novel Combination (New) of Low Dose Oral CyclophoSphamide (s) to Potentiate Axatilimab (A) + Retifanlimab (R) in Treating Metastatic Triple Negative Breast Cancer (TNBC)

Recruiting
NCT04374305Phase 2

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

Recruiting
NCT06179160Phase 1

A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation

Recruiting
NCT05743595Phase 1

Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma

Active Not Recruiting
NCT06610682Early Phase 1

A Trial to Evaluate CSF ctDNA and Safety of Plixorafenib Alone or With Retifanlimab in Patients With BRAF-altered Glioma

Recruiting
NCT04577014Phase 1

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

Recruiting
NCT07468136Phase 1

Retifanlimab With or Without Difluoromethylornithine for the Treatment of Progressive High Grade Gliomas

Not Yet Recruiting
NCT06072612Phase 3

Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.

Recruiting
NCT04205812Phase 3

Platinum-Based Chemotherapy With/Without INCMGA00012, an Anti-PD-1 Antibody, in Non-Small Cell Lung Cancer

Active Not Recruiting
NCT03328026Phase 1

Combination Study of SV-BR-1-GM With Retifanlimab

Completed
NCT05287113Phase 2

Study of Retinfanlimab in Combination With INCAGN02385 and INCAGN02390 as First-Line Treatment in Participants With PD-L1-Positive (CPS ≥ 1) Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

Active Not Recruiting
NCT06873789Phase 1

A Study to Evaluate INCB177054 in Participants With Select Advanced or Metastatic Solid Tumors

Active Not Recruiting
NCT04387084Phase 1

Short-term Fasting Prior to PD-1/PD-L1 Inhibitor Therapy for of Advanced or Metastatic Skin Malignancy

Active Not Recruiting
NCT05345002Phase 2

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

Recruiting
NCT06939036Phase 1

Study of 225Ac-SS0110 in Subjects With ES-SCLC or MCC (SANTANA-225 )

Terminated
NCT06056895Phase 2

Triple Immune Checkpoint Inhibition for Advanced or Metastatic PD-(L)1 Refractory Merkel Cell Carcinoma

Active Not Recruiting
NCT05594290Phase 2

Chemo-immunotherapy in Patients With Resectable Merkel Cell Carcinoma Prior to Surgery

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
54