Success Metrics

Clinical Success Rate
66.7%

Based on 10 completed trials

Completion Rate
67%(10/15)
Active Trials
16(48%)
Results Posted
130%(13 trials)
Terminated
5(15%)

Phase Distribution

Ph not_applicable
1
3%
Ph phase_4
1
3%
Ph phase_3
9
27%
Ph phase_2
13
39%
Ph phase_1
9
27%

Phase Distribution

9

Early Stage

13

Mid Stage

10

Late Stage

Phase Distribution33 total trials
Phase 1Safety & dosage
9(27.3%)
Phase 2Efficacy & side effects
13(39.4%)
Phase 3Large-scale testing
9(27.3%)
Phase 4Post-market surveillance
1(3.0%)
N/ANon-phased studies
1(3.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

62.5%

10 of 16 finished

Non-Completion Rate

37.5%

6 ended early

Currently Active

16

trials recruiting

Total Trials

33

all time

Status Distribution
Active(17)
Completed(10)
Terminated(6)

Detailed Status

Recruiting16
Completed10
Terminated5
Withdrawn1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
33
Active
16
Success Rate
66.7%
Most Advanced
Phase 4

Trials by Phase

Phase 19 (27.3%)
Phase 213 (39.4%)
Phase 39 (27.3%)
Phase 41 (3.0%)
N/A1 (3.0%)

Trials by Status

recruiting1648%
terminated515%
withdrawn13%
not_yet_recruiting13%
completed1030%

Recent Activity

Clinical Trials (33)

Showing 20 of 33 trialsScroll for more
NCT06925737Phase 3

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

Recruiting
NCT06966700Phase 3

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

Recruiting
NCT06890884Phase 2

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

Recruiting
NCT06841354Phase 3

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Recruiting
NCT07697625Phase 1

A Clinical Trial of MK-4082 in Healthy Participants (MK-4082-005)

Recruiting
NCT06863272Phase 1

A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02)

Recruiting
NCT06717347Phase 3

A Study to Evaluate Zilovertamab Vedotin (MK-2140) Combination With Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Rituximab Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Participants With Previously Untreated DLBCL (MK-2140-010)

Recruiting
NCT07252739Phase 2

KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J)

Recruiting
NCT07405151Phase 1

A Clinical Trial of Ifinatamab Deruxtecan in People With Advanced Esophageal Cancer (MK-3475-06F)

Recruiting
NCT06843447Phase 1

A Clinical Study of Raludotatug Deruxtecan in People With Ovarian Cancer (MK-5909-003)

Recruiting
NCT06312137Phase 3

A Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)

Recruiting
NCT06637423Phase 1

A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)

Recruiting
NCT06780098Phase 2

Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)

Recruiting
NCT06780111Phase 1

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06)

Recruiting
NCT06428409Phase 1

A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)

Recruiting
NCT07232602Phase 1

KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

Recruiting
NCT07166666Not Applicable

Study Comparing Atomizerd Midazolam & Fentanyl and Dexmedomidine for Procedural Sedation in Adult and Pediatric Patient (2 to 60 Years Old)

Not Yet Recruiting
NCT01244815Phase 3

Efficacy and Safety of Asenapine Treatment for Pediatric Bipolar Disorder (P06107 Has an Extension [P05898; NCT01349907])(P06107)

Completed
NCT01349907Phase 3

Extension Study of Asenapine [P06107 (NCT01244815)] for Pediatric Bipolar Disorder (P05898)

Completed
NCT03250689Phase 2

Randomized Study Evaluating the Effect of Danirixin on Neutrophil Extracellular Traps (NETs) in Chronic Obstructive Pulmonary Disease (COPD)

Terminated

Drug Details

Intervention Type
DRUG
Total Trials
33