Success Metrics

Clinical Success Rate
98.1%

Based on 53 completed trials

Completion Rate
98%(53/54)
Active Trials
2(3%)
Results Posted
23%(12 trials)
Terminated
1(2%)

Phase Distribution

Ph not_applicable
2
3%
Ph phase_1
29
49%
Ph phase_3
3
5%
Ph phase_4
19
32%

Phase Distribution

29

Early Stage

0

Mid Stage

22

Late Stage

Phase Distribution53 total trials
Phase 1Safety & dosage
29(54.7%)
Phase 3Large-scale testing
3(5.7%)
Phase 4Post-market surveillance
19(35.8%)
N/ANon-phased studies
2(3.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

98.1%

53 of 54 finished

Non-Completion Rate

1.9%

1 ended early

Currently Active

2

trials recruiting

Total Trials

59

all time

Status Distribution
Active(3)
Completed(53)
Terminated(1)
Other(2)

Detailed Status

Completed53
Recruiting2
unknown2
Terminated1
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
59
Active
2
Success Rate
98.1%
Most Advanced
Phase 4

Trials by Phase

Phase 129 (54.7%)
Phase 33 (5.7%)
Phase 419 (35.8%)
N/A2 (3.8%)

Trials by Status

recruiting23%
terminated12%
completed5390%
not_yet_recruiting12%
unknown23%

Recent Activity

Clinical Trials (59)

Showing 20 of 59 trialsScroll for more
NCT07340190Phase 1

A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies

Recruiting
NCT05384626Phase 1

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

Recruiting
NCT06367153Phase 1

A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam and Bupropion in the Blood

Completed
NCT07235748Phase 1

Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvastatin in Healthy Adult Participants

Completed
NCT05444556Phase 1

A Study of Imlunestrant (LY3484356) in Female Healthy Participants

Completed
NCT05469113Phase 1

A Study of Effects of Selpercatinib (LY3527723) on Repaglinide in Healthy Participants

Completed
NCT06494761Phase 1

A Study in Healthy Men to Test Whether Zongertinib Affects How 3 Other Medicines (Midazolam, Omeprazole, and Repaglinide) Are Taken up and Processed by the Body

Completed
NCT06948747Phase 1

A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants

Completed
NCT06165146Phase 1

A Study of the Effects of Pirtobrutinib (LOXO-305) on Repaglinide (CYP2C8 Substrate) in Healthy Participants

Completed
NCT06503679Phase 1

A Drug-drug Interaction Study Evaluating the Perpetrator Potential of LY4100511 (DC-853) on Midazolam, Repaglinide, Digoxin, Rosuvastatin in Healthy Participants

Completed
NCT05981365Phase 1

Voxelotor CYP and Transporter Cocktail Interaction Study

Completed
NCT06601517Phase 1

A Drug-Drug Interaction (DDI) Study of HDM1002 With Repaglinide, Atorvastatin, Digoxin and Rosuvastatin in Healthy Subjects and Overweight Subjects.

Not Yet Recruiting
NCT04530981Phase 1

A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST

Completed
NCT06290050Phase 1

A Study of the Interaction of Other Drugs With TAK-279 in Healthy Adults

Completed
NCT06092931Phase 1

A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants

Completed
NCT00745433

Switch From Metformin Monotherapy to a Bitherapy With Metformin and Repaglinide

Completed
NCT05555823Phase 1

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Food Effect and DDI of Ascending Doses of the MEK Inhibitor Zapnometinib

Completed
NCT03028103Phase 1

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Completed
NCT05602675Phase 1

A Drug Interaction Study of LY3871801 in Healthy Participants

Completed
NCT05236530Phase 1

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Completed

Drug Details

Intervention Type
DRUG
Total Trials
59