Success Metrics

Clinical Success Rate
98.1%

Based on 53 completed trials

Completion Rate
98%(53/54)
Active Trials
0(0%)
Results Posted
21%(11 trials)
Terminated
1(2%)

Phase Distribution

Ph phase_4
19
33%
Ph not_applicable
2
3%
Ph phase_1
28
48%
Ph phase_3
3
5%

Phase Distribution

28

Early Stage

0

Mid Stage

22

Late Stage

Phase Distribution52 total trials
Phase 1Safety & dosage
28(53.8%)
Phase 3Large-scale testing
3(5.8%)
Phase 4Post-market surveillance
19(36.5%)
N/ANon-phased studies
2(3.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

98.1%

53 of 54 finished

Non-Completion Rate

1.9%

1 ended early

Currently Active

0

trials recruiting

Total Trials

58

all time

Status Distribution
Active(2)
Completed(53)
Terminated(1)
Other(2)

Detailed Status

Completed53
Not yet recruiting2
unknown2
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
58
Active
0
Success Rate
98.1%
Most Advanced
Phase 4

Trials by Phase

Phase 128 (53.8%)
Phase 33 (5.8%)
Phase 419 (36.5%)
N/A2 (3.8%)

Trials by Status

not_yet_recruiting23%
unknown23%
terminated12%
completed5391%

Recent Activity

Clinical Trials (58)

Showing 20 of 58 trialsScroll for more
NCT07340190Phase 1

A Drug-drug Interaction Study to Evaluate the Effects of Pelabresib on the Pharmacokinetics of Repaglinide, Midazolam, and Combined Oral Contraceptive in Patients With Advanced Malignancies

Not Yet Recruiting
NCT07235748Phase 1

Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvastatin in Healthy Adult Participants

Completed
NCT05444556Phase 1

A Study of Imlunestrant (LY3484356) in Female Healthy Participants

Completed
NCT05469113Phase 1

A Study of Effects of Selpercatinib (LY3527723) on Repaglinide in Healthy Participants

Completed
NCT06494761Phase 1

A Study in Healthy Men to Test Whether Zongertinib Affects How 3 Other Medicines (Midazolam, Omeprazole, and Repaglinide) Are Taken up and Processed by the Body

Completed
NCT06948747Phase 1

A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants

Completed
NCT06165146Phase 1

A Study of the Effects of Pirtobrutinib (LOXO-305) on Repaglinide (CYP2C8 Substrate) in Healthy Participants

Completed
NCT06503679Phase 1

A Drug-drug Interaction Study Evaluating the Perpetrator Potential of LY4100511 (DC-853) on Midazolam, Repaglinide, Digoxin, Rosuvastatin in Healthy Participants

Completed
NCT05981365Phase 1

Voxelotor CYP and Transporter Cocktail Interaction Study

Completed
NCT06367153Phase 1

A Study in Healthy Men and Women to Test Whether BI 1569912 Influences the Amount of Repaglinide, Midazolam and Bupropion in the Blood

Completed
NCT06601517Phase 1

A Drug-Drug Interaction (DDI) Study of HDM1002 With Repaglinide, Atorvastatin, Digoxin and Rosuvastatin in Healthy Subjects and Overweight Subjects.

Not Yet Recruiting
NCT04530981Phase 1

A Drug-Drug Interaction Study to Evaluate the Effect of Ripretinib on the Pharmacokinetics of a CYP2C8 Probe Substrate in Patients with Advanced GIST

Completed
NCT06290050Phase 1

A Study of the Interaction of Other Drugs With TAK-279 in Healthy Adults

Completed
NCT06092931Phase 1

A Drug-Drug Interaction Study Evaluating the Perpetrator Potential of DC-806 on Cocktails of CYP450 Enzyme and Transporter Substrates in Healthy Participants

Completed
NCT00745433

Switch From Metformin Monotherapy to a Bitherapy With Metformin and Repaglinide

Completed
NCT05555823Phase 1

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Food Effect and DDI of Ascending Doses of the MEK Inhibitor Zapnometinib

Completed
NCT03028103Phase 1

Open-Label, Multicenter, Two-Part, Phase 1 Study to Characterize Effects of a Moderate CYP3A Inhibitor on PK of Tazemetostat, Effects of Tazemetostat on PK of CYP2C8 and CYP2C19 Substrates, and Effect of Increased Gastric pH on PK of Tazemetostat in B-cell Lymphoma or Advanced Solid Tumor Patients

Completed
NCT05602675Phase 1

A Drug Interaction Study of LY3871801 in Healthy Participants

Completed
NCT05236530Phase 1

Drug-drug Interaction Study of Ganaplacide and Lumefantrine With Midazolam, Repaglinide, Dextromethorphan, Metformin, Rosuvastatin and Dolutegravir

Completed
NCT04457180Phase 1

A Pharmacokinetic Interaction Study Between Apatinib Mesylate and Repaglinide or Bupropion in Advanced Solid Tumor Subjects

Completed

Drug Details

Intervention Type
DRUG
Total Trials
58