Success Metrics

Clinical Success Rate
67.9%

Based on 19 completed trials

Completion Rate
68%(19/28)
Active Trials
8(14%)
Results Posted
11%(2 trials)
Terminated
9(16%)

Phase Distribution

Ph not_applicable
32
57%
Ph early_phase_1
1
2%
Ph phase_1
1
2%
Ph phase_2
6
11%
Ph phase_3
3
5%
Ph phase_4
5
9%

Phase Distribution

2

Early Stage

6

Mid Stage

8

Late Stage

Phase Distribution48 total trials
Early Phase 1First-in-human
1(2.1%)
Phase 1Safety & dosage
1(2.1%)
Phase 2Efficacy & side effects
6(12.5%)
Phase 3Large-scale testing
3(6.3%)
Phase 4Post-market surveillance
5(10.4%)
N/ANon-phased studies
32(66.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

63.3%

19 of 30 finished

Non-Completion Rate

36.7%

11 ended early

Currently Active

8

trials recruiting

Total Trials

56

all time

Status Distribution
Active(11)
Completed(19)
Terminated(11)
Other(15)

Detailed Status

Completed19
unknown15
Terminated9
Recruiting5
Not yet recruiting3
Active, not recruiting3

Development Timeline

Analytics

Development Status

Total Trials
56
Active
8
Success Rate
67.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.1%)
Phase 11 (2.1%)
Phase 26 (12.5%)
Phase 33 (6.3%)
Phase 45 (10.4%)
N/A32 (66.7%)

Trials by Status

completed1934%
not_yet_recruiting35%
terminated916%
unknown1527%
withdrawn24%
recruiting59%
active_not_recruiting35%

Recent Activity

8 active trials
Showing 5 of 56
active_not_recruitingnot_applicable

Renal Denervation in ADPKD- RDN-ADPKD Study

NCT05460169
terminatednot_applicable

Renal Denervation in Patients With Recurrent Atrial Fibrillation After Successful Pulmonary Vein Isolation

NCT05817318
completednot_applicable

Renal Denervation in Chronic Kidney Disease - RDN-CKD Study

NCT04264403
not_yet_recruitingnot_applicable

RDN for Heart Failure

NCT07558902
terminated

The Long-term Safety and Effect of Renal Denervation

NCT05818813
View all 56 trials

Clinical Trials (56)

Showing 20 of 56 trialsScroll for more
NCT05460169Not Applicable

Renal Denervation in ADPKD- RDN-ADPKD Study

Active Not Recruiting
NCT05817318Not Applicable

Renal Denervation in Patients With Recurrent Atrial Fibrillation After Successful Pulmonary Vein Isolation

Terminated
NCT04264403Not Applicable

Renal Denervation in Chronic Kidney Disease - RDN-CKD Study

Completed
NCT07558902Not Applicable

RDN for Heart Failure

Not Yet Recruiting
NCT05818813

The Long-term Safety and Effect of Renal Denervation

Terminated
NCT06783296Not Applicable

Efficacy and Safety of Renal Denervation on Isolated Diastolic Hypertension

Not Yet Recruiting
NCT07320768Not Applicable

Renal Denervation Combined With Pulsed Field Ablation to Prevent Blanking-Period Recurrence in Persistent Atrial Fibrillation

Not Yet Recruiting
NCT05372679Not Applicable

REDUCED 1 - Renal Denervation Using Ultrasonic Catheter EmitteD Energy Study /

Active Not Recruiting
NCT05988411Not Applicable

ULTRA-HFIB-Redo: Ultrasound-based Renal Sympathetic Denervation vs Control in Redo Ablation Patients

Recruiting
NCT06556407Not Applicable

Effect of Renal Denervation on Bood Pressure in Patients on Hemodialysis

Recruiting
NCT04314557

Renal Arterial Denervation in Sympathetic Dysautonomia

Completed
NCT04182620Not Applicable

Ultrasound-Based Renal Sympathetic Denervation as Adjunctive Upstream Therapy During Atrial Fibrillation Ablation

Completed
NCT05030987Not Applicable

Renal Denervation to Treat Heart Failure With Preserved Ejection Fraction

Recruiting
NCT05017935Not Applicable

RADIANCE Continued Access Protocol

Active Not Recruiting
NCT04307836Not Applicable

DENEX, Renal Denervation Therapy, in Patients With Hypertension on no or 1-3 Antihypertensive Medications

Unknown
NCT02021019Not Applicable

Renal Denervation to Improve Outcomes in Patients With End-stage Renal Disease

Completed
NCT02444442Not Applicable

Sham Controlled Clinical Trial of Renal Denervation in Patients With Resistant Hypertension

Completed
NCT04535050Not Applicable

DENEX Renal Denervation in Patients With Hypertension on no Antihypertensive Medications

Recruiting
NCT05703620Not Applicable

REducing Sympathetic Activity Through Ultrasound-based Renal deneRvation in Excessive Cardiovascular Risk populaTions.

Recruiting
NCT01990911Not Applicable

Renal Sympathetic Denervation Prevents Atrial Fibrillation in Patients With Hypertensive Heart Disease: a Pilot Study

Completed

Drug Details

Intervention Type
DEVICE
Total Trials
56