Success Metrics

Clinical Success Rate
87.5%

Based on 28 completed trials

Completion Rate
88%(28/32)
Active Trials
1(3%)
Results Posted
43%(12 trials)
Terminated
4(12%)

Phase Distribution

Ph phase_1
10
30%
Ph phase_4
2
6%
Ph phase_2
7
21%
Ph phase_3
4
12%

Phase Distribution

10

Early Stage

7

Mid Stage

6

Late Stage

Phase Distribution23 total trials
Phase 1Safety & dosage
10(43.5%)
Phase 2Efficacy & side effects
7(30.4%)
Phase 3Large-scale testing
4(17.4%)
Phase 4Post-market surveillance
2(8.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

87.5%

28 of 32 finished

Non-Completion Rate

12.5%

4 ended early

Currently Active

1

trials recruiting

Total Trials

33

all time

Status Distribution
Active(1)
Completed(28)
Terminated(4)

Detailed Status

Completed28
Terminated4
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
33
Active
1
Success Rate
87.5%
Most Advanced
Phase 4

Trials by Phase

Phase 110 (43.5%)
Phase 27 (30.4%)
Phase 34 (17.4%)
Phase 42 (8.7%)

Trials by Status

terminated412%
active_not_recruiting13%
completed2885%

Recent Activity

Clinical Trials (33)

Showing 20 of 33 trialsScroll for more
NCT06246643Phase 2

A Study of Continued Treatment With Regorafenib in Participants With Solid Tumors Who Have Participated in Other Bayer Studies

Active Not Recruiting
NCT06137170

A Real-World Study to Learn More About the Order of Different Treatments and Their Effects in People With Metastatic Colorectal Cancer Receiving Their Third and Fourth Line of Treatment

Completed
NCT06321055

An Observational Study to Learn More About Treatment With Regorafenib in People With Advanced Gastrointestinal Stromal Tumors in the United States

Completed
NCT04696055Phase 2

Regorafenib Plus Pembrolizumab in Patients With Advanced or Spreading Liver Cancer Who Have Been Previously Treated With PD-1/PD-L1 Immune Checkpoint Inhibitors

Completed
NCT04704154Phase 2

A Trial to Learn Whether Regorafenib in Combination With Nivolumab Can Improve Tumor Responses and How Safe it is for Participants With Solid Tumors

Completed
NCT06029010

An Observational Study to Learn More About the Long-Term Responses to Treatment With Regorafenib in Patients With Metastatic Colorectal Cancer in the United States

Completed
NCT03564938Phase 4

Regorafenib in Indian Patients With Metastatic Colorectal Cancer (mCRC).

Completed
NCT04126733Phase 2

Study on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)

Completed
NCT03289273

Observational Study to Evaluate, Under Real-world Practice Conditions, the Safety and Effectiveness of Regorafenib in Patients Diagnosed With Unresectable Hepatocellular Carcinoma (uHCC)

Completed
NCT01933958

Regorafenib Post-marketing Surveillance in Japan

Completed
NCT00664326Phase 2

A Phase II Uncontrolled Study of BAY73-4506 in Previously Untreated Patients With Metastatic or Unresectable RCC

Completed
NCT01271712Phase 3

Study of Regorafenib as a 3rd-line or Beyond Treatment for Gastrointestinal Stromal Tumors (GIST)

Completed
NCT03644511

Use of Sorafenib and/or Regorafenib in Liver Cancer (Hepatocellular Carcinoma) Subsequent to Another Systemic First-line Treatment

Terminated
NCT01774344Phase 3

Study of Regorafenib After Sorafenib in Patients With Hepatocellular Carcinoma

Completed
NCT01287598Phase 1

BAY73-4506 Probe Substrate Study

Completed
NCT02106845Phase 1

Effect of Regorafenib on Digoxin and Rosuvastatin in Patients With Advanced Solid Malignant Tumors.

Completed
NCT01973868Phase 1

Safety and Pharmacokinetics of Regorafenib and Cetuximab in Combination

Completed
NCT02465502Phase 2

Regorafenib in Subjects With Antiangiogenic-naive and Chemotherapy-refractory Advanced Colorectal Cancer

Completed
NCT02347852

Assessment of Physical Activity During Therapy With Regorafenib for Metastatic Colorectal Cancer

Completed
NCT01843400

Regorafenib Post-marketing Surveillance

Completed

Drug Details

Intervention Type
DRUG
Total Trials
33