Success Metrics

Clinical Success Rate
100.0%

Based on 6 completed trials

Completion Rate
100%(6/6)
Active Trials
4(17%)
Results Posted
0%(0 trials)

Phase Distribution

Ph phase_3
3
13%
Ph phase_1
5
21%
Ph phase_2
16
67%

Phase Distribution

5

Early Stage

16

Mid Stage

3

Late Stage

Phase Distribution24 total trials
Phase 1Safety & dosage
5(20.8%)
Phase 2Efficacy & side effects
16(66.7%)
Phase 3Large-scale testing
3(12.5%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

6 of 6 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

4

trials recruiting

Total Trials

24

all time

Status Distribution
Active(5)
Completed(6)
Other(13)

Detailed Status

unknown13
Completed6
Recruiting4
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
24
Active
4
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 15 (20.8%)
Phase 216 (66.7%)
Phase 33 (12.5%)

Trials by Status

unknown1354%
recruiting417%
completed625%
not_yet_recruiting14%

Recent Activity

Clinical Trials (24)

Showing 20 of 24 trialsScroll for more
NCT05135715Phase 2

A Study of RC48-ADC in Advanced Melanoma Subjects With HER2 Variant (Mutation, Amplification, Overexpression)

Unknown
NCT03500380Phase 2

A Study of RC48-ADC Administered Intravenously to Patients With HER2-Positive Metastatic Breast Cancer With or Without Liver Metastases

Unknown
NCT05297552Phase 2

A Study of RC48-ADC Combined With JS001 For Perioperative Treatment of Muscle-Invasive Bladder Cancer

Recruiting
NCT04400695Phase 3

A Study of RC48-ADC for the Treatment of Locally Advanced or Metastatic Breast Cancer With Low Expression of HER2

Unknown
NCT05403242Phase 1

RC48-ADC Combined With S-1 for First-line Treatment of Advanced Gastroesophageal Adenocarcinoma With Moderate Expression of HER2

Recruiting
NCT06178601Phase 2

A Study of RC48-ADC Combined With Cadonilimab(AK104)in the Treatment of HER2-expression Locally Advanced or Metastatic Urothelial Carcinoma

Recruiting
NCT04714190Phase 3

A Study of RC48-ADC in Local Advanced or Metastatic Gastric Cancer With the HER2-Overexpression

Unknown
NCT04329429Phase 2

A Study of RC48-ADC in Subjects With HER2 Overexpressed Metastatic Biliary Tract Cancer

Unknown
NCT04073602Phase 2

A Study of RC48-ADC in Subjects With HER2-negative Locally Advanced or Metastatic Urothelial Cancer

Completed
NCT05302284Phase 3

A Study of RC48-ADC Combined With Toripalimab For First-line Treatment of Urothelial Carcinoma

Recruiting
NCT04965519Phase 2

A Study of RC48-ADC for the Treatment of HER2-expressing Gynecological Malignancies

Unknown
NCT05514158Phase 1

To Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Disitamab Vedotin Combined With RC98 in the Treatment of Subjects With HER2-expressing Locally Advanced or Metastatic Gastric Cancer (Including AEG)

Unknown
NCT03809013Phase 2

A Open-label, Single-arm, Multicenter, Phase II Study of RC48-ADC to Evaluate the Efficacy and Safety of Subjects With HER2 Overexpressing Locally Advanced or Metastatic Urothelial Cancer

Completed
NCT05745740Phase 1

A Study of RC48-ADC Combined With Pyrotinib For Treatment of Local Advanced or Metastasis NSCLC With HER2 Mutation

Unknown
NCT06074484Phase 2

A Study of RC48-ADC Combined With AK104 For Perioperative Treatment of Muscle-Invasive Bladder Cancer

Unknown
NCT05996952Phase 2

RC48-ADC in Adjuvant/Salvage Treatment of HER2 Positive Non-muscle-invasive Bladder Cancer

Not Yet Recruiting
NCT05601401Phase 2

Phase II Study of RC48-ADC in Treating Patients With Salivary Gland Tumors Expressing HER2

Unknown
NCT05417230Phase 2

RC48-ADC Combinatioed Envolizumab in Locally Advanced or Metastatic Biliary Tract Cancer With Positive HER-2

Unknown
NCT05331326Phase 2

A Study of RC48-ADC for the Treatment of HER2-expression Metastatic Breast Cancer With Abnormal Activation of PAM Pathway

Unknown
NCT03556345Phase 2

A Study of RC48-ADC in Local Advanced or Metastatic Gastric Cancer Subjects With the Overexpression of HER2

Completed

Drug Details

Intervention Type
DRUG
Total Trials
24