Success Metrics

Clinical Success Rate
87.0%

Based on 20 completed trials

Completion Rate
87%(20/23)
Active Trials
1(4%)
Results Posted
50%(10 trials)
Terminated
3(12%)

Phase Distribution

Ph phase_1
6
24%
Ph phase_3
3
12%
Ph phase_4
1
4%
Ph phase_2
5
20%

Phase Distribution

6

Early Stage

5

Mid Stage

4

Late Stage

Phase Distribution15 total trials
Phase 1Safety & dosage
6(40.0%)
Phase 2Efficacy & side effects
5(33.3%)
Phase 3Large-scale testing
3(20.0%)
Phase 4Post-market surveillance
1(6.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

83.3%

20 of 24 finished

Non-Completion Rate

16.7%

4 ended early

Currently Active

1

trials recruiting

Total Trials

25

all time

Status Distribution
Active(1)
Completed(20)
Terminated(4)

Detailed Status

Completed20
Terminated3
Active, not recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
25
Active
1
Success Rate
87.0%
Most Advanced
Phase 4

Trials by Phase

Phase 16 (40.0%)
Phase 25 (33.3%)
Phase 33 (20.0%)
Phase 41 (6.7%)

Trials by Status

completed2080%
active_not_recruiting14%
terminated312%
withdrawn14%

Recent Activity

Clinical Trials (25)

Showing 20 of 25 trialsScroll for more
NCT04597125Phase 4

RADIANT: A Study of Radium-223 Dichloride (Xofigo) vs Enzalutamide or Abiraterone (ARPIs, Androgen Receptor Pathway Inhibitors) in Patients With Prostate Cancer That Has Spread to the Bones (mCRPC, Metastatic Castration-Resistant Prostate Cancer)

Active Not Recruiting
NCT00699751Phase 3

A Phase III Study of Radium-223 Dichloride in Patients With Symptomatic Hormone Refractory Prostate Cancer With Skeletal Metastases

Completed
NCT02141438

Observational Study for the Evaluation of Long-term Safety of Radium-223 Used for the Treatment of Metastatic Castration Resistant Prostate Cancer

Completed
NCT04521361Phase 1

A Study to Assess How Radium-223 Distributes in the Body of Patients With Prostate Cancer Which Spread to the Bones

Completed
NCT02043678Phase 3

Radium-223 Dichloride and Abiraterone Acetate Compared to Placebo and Abiraterone Acetate for Men With Cancer of the Prostate When Medical or Surgical Castration Does Not Work and When the Cancer Has Spread to the Bone, Has Not Been Treated With Chemotherapy and is Causing no or Only Mild Symptoms

Completed
NCT04232761

Study to Gather Information on the Safety and How Radium-223 Dichloride, an Alpha Particle-emitting Radioactive Agent, Works Under Routine Clinical Practice in Taiwan in Patients With Castration-resistant Prostate Cancer (CRPC) Which Has Spread to the Bone

Completed
NCT03315260

Treatment Satisfaction With Ra-223 in Japan

Completed
NCT04256993

PRECISE, a Study to Gather More Information About Bone Fractures and Survival in Castration-resistant PRostate Cancer (CRPC) patiEnts Treated With Radium-223 in Routine Clinical practIce in SwedEn

Completed
NCT02258451Phase 2

Study of Radium-223 Dichloride in Combination With Exemestane and Everolimus Versus Placebo in Combination With Exemestane and Everolimus in Subjects With Bone Predominant HER2 Negative Hormone Receptor Positive Metastatic Breast Cancer

Completed
NCT05301062

A Research Called CREDIT Studies How Safe the Study Treatment Radium-223 is and How Well it Works in Chinese Men With Advanced Prostate Cancer That Has Spread to the Bones and Does Not Respond to Treatments for Lowering Testosterone Levels

Terminated
NCT04281147

Study to Gather Information About the Use of Healthcare Services and the Way the Disease is Cared for in Canadian Patients With Prostate Gland Cancer Which Spread Throughout the Body

Completed
NCT04516161

EPIX, a Study to Gather More Information About Characteristics of Patients and Other Factors Which May Contribute to Survival Over a Long Period of Time in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Treated With Radium-223 (Xofigo)

Completed
NCT02398526

Pain Evaluation in Radium-223 Treated Castration Resistant Prostate Cancer Patients With Bone Metastases

Completed
NCT02258464Phase 2

Study of Radium-223 Dichloride Versus Placebo and Hormonal Treatment as Background Therapy in Subjects With Bone Predominant HER2 (Human Epidermal Growth Factor Receptor 2) Negative Hormone Receptor Positive Metastatic Breast Cancer

Terminated
NCT02928029Phase 1

Study Testing Radium-223 Dichloride in Relapsed Multiple Myeloma

Terminated
NCT02034552Phase 2

A Randomized Phase IIa Efficacy and Safety Study of Radium-223 Dichloride With Abiraterone Acetate or Enzalutamide in Metastatic Castration-resistant Prostate Cancer (CRPC)

Completed
NCT02023697Phase 2

Standard Dose Versus High Dose and Versus Extended Standard Dose Radium-223 Dichloride in Castration-resistant Prostate Cancer Metastatic to the Bone

Completed
NCT01810770Phase 3

Radium-223 Dichloride Asian Population Study in the Treatment of CRPC Patients With Bone Metastasis

Completed
NCT02518698

Treatment Patterns in Castrate Resistant Prostate Cancer Patients With Bone Metastases in a Medicare Population

Completed
NCT01929655Phase 2

Japanese BAY88-8223 Monotherapy Phase II Study

Completed

Drug Details

Intervention Type
DRUG
Total Trials
25