Success Metrics

Clinical Success Rate
85.0%

Based on 17 completed trials

Completion Rate
85%(17/20)
Active Trials
13(37%)
Results Posted
65%(11 trials)
Terminated
3(9%)

Phase Distribution

Ph early_phase_1
1
3%
Ph phase_2
13
37%
Ph not_applicable
12
34%
Ph phase_1
6
17%
Ph phase_3
1
3%

Phase Distribution

7

Early Stage

13

Mid Stage

1

Late Stage

Phase Distribution33 total trials
Early Phase 1First-in-human
1(3.0%)
Phase 1Safety & dosage
6(18.2%)
Phase 2Efficacy & side effects
13(39.4%)
Phase 3Large-scale testing
1(3.0%)
N/ANon-phased studies
12(36.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

81.0%

17 of 21 finished

Non-Completion Rate

19.0%

4 ended early

Currently Active

13

trials recruiting

Total Trials

35

all time

Status Distribution
Active(13)
Completed(17)
Terminated(4)
Other(1)

Detailed Status

Completed17
Active, not recruiting11
Terminated3
Recruiting2
Withdrawn1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
35
Active
13
Success Rate
85.0%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (3.0%)
Phase 16 (18.2%)
Phase 213 (39.4%)
Phase 31 (3.0%)
N/A12 (36.4%)

Trials by Status

withdrawn13%
recruiting26%
terminated39%
active_not_recruiting1131%
completed1749%
unknown13%

Recent Activity

Clinical Trials (35)

Showing 20 of 35 trialsScroll for more
NCT06172296Phase 3

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

Recruiting
NCT06357988Phase 2

Testing GDC-0449 (Vismodegib) as Potentially Targeted Treatment in Cancers With Smoothened or Patched 1 Mutant Tumors (MATCH - Subprotocol T)

Active Not Recruiting
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT06400225Phase 2

Testing BVD-523FB (Ulixertinib) as Potentially Targeted Treatment in Cancers With Genetic Changes (MATCH - Subprotocol Z1L)

Active Not Recruiting
NCT02465060Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)

Active Not Recruiting
NCT04320888Phase 2

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Active Not Recruiting
NCT06390826Phase 2

Testing Sunitinib as Potentially Targeted Treatment in Cancers With cKIT Genetic Changes (MATCH - Subprotocol V)

Active Not Recruiting
NCT06385483Phase 2

Testing Afatinib as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH - Subprotocol A)

Active Not Recruiting
NCT03213704Phase 2

Larotrectinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT03210714Phase 2

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT03213652Phase 2

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT02293954Not Applicable

Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer

Active Not Recruiting
NCT06287944Phase 1

225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

Recruiting
NCT00003800Not Applicable

Diagnostic Study of Patients With Stage I Testicular Cancer

Completed
NCT00003763Not Applicable

Radiolabeled Folic Acid and Imaging to Detect Ovarian Cancer

Completed
NCT00003654Not Applicable

Diagnostic Study to Identify Sentinel Lymph Nodes in Women With Stage I or Stage II Breast Cancer

Terminated
NCT00645060Phase 1

Yttrium Y 90 DOTA Anti-CEA Monoclonal Antibody M5A in Treating Patients With Advanced Solid Tumors

Completed
NCT01789827Early Phase 1

Aldesleukin Imaging in Viewing Tumor Growth in Patients With Stage IV Melanoma Receiving Ipilimumab or Pembrolizumab Therapy

Completed
NCT00738452Phase 1

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Stage I-IIIB Non-Small Cell Lung Cancer After Completion of Radiation Therapy Alone or Combined Radiation Therapy and Chemotherapy

Completed
NCT00070317Not Applicable

Lymph Node Mapping and Sentinel Lymph Node Identification in Patients With Stage IB1 Cervical Cancer

Terminated

Drug Details

Intervention Type
PROCEDURE
Total Trials
35