Success Metrics

Clinical Success Rate
79.3%

Based on 65 completed trials

Completion Rate
79%(65/82)
Active Trials
1(1%)
Results Posted
65%(42 trials)
Terminated
17(19%)

Phase Distribution

Ph early_phase_1
1
1%
Ph phase_3
4
4%
Ph phase_1
44
49%
Ph phase_2
36
40%
Ph phase_4
4
4%

Phase Distribution

45

Early Stage

36

Mid Stage

8

Late Stage

Phase Distribution89 total trials
Early Phase 1First-in-human
1(1.1%)
Phase 1Safety & dosage
44(49.4%)
Phase 2Efficacy & side effects
36(40.4%)
Phase 3Large-scale testing
4(4.5%)
Phase 4Post-market surveillance
4(4.5%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

77.4%

65 of 84 finished

Non-Completion Rate

22.6%

19 ended early

Currently Active

1

trials recruiting

Total Trials

89

all time

Status Distribution
Active(1)
Completed(65)
Terminated(19)
Other(4)

Detailed Status

Completed65
Terminated17
unknown4
Withdrawn2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
89
Active
1
Success Rate
79.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.1%)
Phase 144 (49.4%)
Phase 236 (40.4%)
Phase 34 (4.5%)
Phase 44 (4.5%)

Trials by Status

withdrawn22%
active_not_recruiting11%
terminated1719%
unknown44%
completed6573%

Recent Activity

Clinical Trials (89)

Showing 20 of 89 trialsScroll for more
NCT00819546Phase 1

RAD001 in Combination With PKC412 in Patients With Relapsed, Refractory or Poor Prognosis AML or MDS

Active Not Recruiting
NCT04895748Phase 1

DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

Terminated
NCT00087685Phase 2

RAD001 in Recurrent Endometrial Cancer Patients

Completed
NCT00113360Phase 2

RAD001 Plus Octreotide Depot in Metastatic or Unresectable Low Grade Neuroendocrine Carcinoma

Completed
NCT00640978Phase 2

Erlotinib and RAD001 (Everolimus) in Patients With Previously Treated Advanced Pancreatic Cancer

Terminated
NCT00942734Phase 2

Trial of RAD001 and Erlotinib With Recurrent Head and Neck Squamous Cell Carcinoma

Completed
NCT00317720Phase 1

Trastuzumab and RAD001 in Patients With Human Epidermal Growth Receptor 2 (HER-2) Overexpressing Breast Cancer

Completed
NCT00081874Phase 1

RAD001 in Relapsed or Refractory AML, ALL, CML in Blastic-Phase, Agnogenic Myeloid Metaplasia, CLL, T-Cell Leukemia, or Mantle Cell Lymphoma

Completed
NCT00253318Phase 1

RAD001 Plus Docetaxel in Patients With Metastatic Breast Cancer

Terminated
NCT02991807Phase 1

RAD001 and Neurocognition in PTEN Hamartoma Tumor Syndrome

Completed
NCT00830895Phase 2

RAD001 for Non-clear Cell Renal Cell Carcinoma (RCC)

Completed
NCT00392821Phase 1

Dosing and Effectiveness Study of Sorafenib and RAD001 in the Treatment of Patients With Advanced Kidney Cancer

Completed
NCT00936858Phase 2

RAD001 for Patients With Radioiodine Refractory Thyroid Cancer

Completed
NCT01275222Phase 1

Everolimus in Combination With Imatinib in Patients With Glivec Refractory/Resistant Gastrointestinal Stromal Tumors

Completed
NCT00456833Phase 1

Combination of RAD001 and Erlotinib in Patients With Advanced Non Small Cell Lung Cancer Previously Treated Only With Chemotherapy

Completed
NCT00843531Phase 2

RAD001 and Erlotinib in Patients With Neuroendocrine Tumors

Terminated
NCT00576680Phase 1

RAD001 and Temozolomide in Patients With Advanced Pancreatic Neuroendocrine Tumors

Completed
NCT01880749Early Phase 1

Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas

Completed
NCT01510119Phase 1

Autophagy Inhibition to Augment Mammilian Target of Rapamycin (mTOR) Inhibition: A Phase I/II Trial of RAD001 and Hydroxychloroquine (HCQ) in Patients With Previously Treated Renal Cell Carcinoma

Completed
NCT01248403Phase 3

A Randomized, Double Blind Study Evaluating Paclitaxel With and Without RAD001 in Patients With Gastric Carcinoma After Prior Chemotherapy

Completed

Drug Details

Intervention Type
DRUG
Total Trials
89