Success Metrics

Clinical Success Rate
85.7%

Based on 6 completed trials

Completion Rate
86%(6/7)
Active Trials
23(27%)
Results Posted
0%(0 trials)
Terminated
1(1%)

Phase Distribution

Ph not_applicable
5
6%
Ph phase_2
51
61%
Ph phase_1
7
8%
Ph phase_3
11
13%
Ph phase_4
1
1%

Phase Distribution

7

Early Stage

51

Mid Stage

12

Late Stage

Phase Distribution75 total trials
Phase 1Safety & dosage
7(9.3%)
Phase 2Efficacy & side effects
51(68.0%)
Phase 3Large-scale testing
11(14.7%)
Phase 4Post-market surveillance
1(1.3%)
N/ANon-phased studies
5(6.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

85.7%

6 of 7 finished

Non-Completion Rate

14.3%

1 ended early

Currently Active

23

trials recruiting

Total Trials

84

all time

Status Distribution
Active(37)
Completed(6)
Terminated(1)
Other(40)

Detailed Status

unknown40
Recruiting19
Not yet recruiting14
Completed6
Active, not recruiting4
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
84
Active
23
Success Rate
85.7%
Most Advanced
Phase 4

Trials by Phase

Phase 17 (9.3%)
Phase 251 (68.0%)
Phase 311 (14.7%)
Phase 41 (1.3%)
N/A5 (6.7%)

Trials by Status

completed67%
recruiting1923%
not_yet_recruiting1417%
terminated11%
unknown4048%
active_not_recruiting45%

Recent Activity

Clinical Trials (84)

Showing 20 of 84 trialsScroll for more
NCT06563999Phase 2

Neoadjuvant Umbrella Trial for Patients With Unresectable Stage III NSCLC Harboring Rare Mutations.

Recruiting
NCT05769010Phase 2

Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases

Recruiting
NCT07335081Phase 2

ctDNA in HER2+ EBC Neoadjuvant Treatment

Recruiting
NCT06495541Not Applicable

The Real World Study of Pyrotinib in the Treatment of Advanced Breast Cancer With HER2 Positive

Not Yet Recruiting
NCT07470203

Pyrotinib Combined With Trastuzumab and Pertuzumab for Maintenance Therapy in HER2-Positive Advanced Breast Cancer

Not Yet Recruiting
NCT07417241Phase 2

SHR-A1811 vs Pyrotinib/Capecitabine in Trastuzumab-Resistant HER2+ Advanced Breast Cancer: A Randomized Study

Not Yet Recruiting
NCT07340398Phase 2

Neoadjuvant Trastuzumab-rezetecan Plus Pertuzumab or Nab-Paclitaxel, Carboplatin, Trastuzumab, and Pyrotinib After Suboptimal Response to Neoadjuvant Dual HER2-Targeted Therapy Combined With Chemotherapy in HER2-Positive Early Breast Cancer

Recruiting
NCT04290793Phase 2

Neoadjuvant Chemotherapy With Pyrotinib, Epirubicin and Cyclophosphamide Followed by Taxanes and Trastuzumab for HER-2+ Breast Cancer

Active Not Recruiting
NCT04872985Phase 2

Pyrotinib Plus Neoadjuvant Chemotherapy in HR+/HER2-, HER4-High Breast Cancer

Active Not Recruiting
NCT04447118Phase 3

Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy

Completed
NCT05751018Phase 2

Phase II Clinical Study of Pyrotinib in First-line Treatment of Primary HER2-amplified/Mutated Advanced Non-small Cell Lung Cancer

Recruiting
NCT07180082Phase 2

Continuous or Intermittent Pyrotinib for HER2-positive Advanced Breast Cancer

Recruiting
NCT05910398Phase 3

Continuous or Intermittent Extension of Adjuvant Pyrotinib for Invasive HER2-positive Breast Cancer

Recruiting
NCT07179939Phase 2

Maintenance Therapy in HER2-Positive Unresectable Locally Recurrent or Metastatic Breast Cancer: A Phase II Study

Not Yet Recruiting
NCT04254263Phase 3

Adjuvant Study of Pyrotinib in HER-2 Positive Breast Cancer

Recruiting
NCT04126525Phase 2

Neoadjuvant Study of Pyrotinib in HER-2 Positive Breast Cancer

Active Not Recruiting
NCT02834936Phase 2

A Clinica Study of Pyrotinib in Patients of Advanced Non-Small Cell Lung Cancer With HER2 Mutation

Completed
NCT05582499Phase 2

Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy

Recruiting
NCT03588091Phase 3

Neoadjuvant Study of Pyrotinib in Combination With Trastuzumab in Patients With HER2 Positive Breast Cancer

Completed
NCT07065435Phase 2

RC48 Plus Bevacizumab or Pyrotinib in HER2-Positive Metastatic Breast Cancer After T-DXd Failure: A Phase II Study

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
84