Success Metrics

Clinical Success Rate
100.0%

Based on 8 completed trials

Completion Rate
100%(8/8)
Active Trials
3(20%)
Results Posted
38%(3 trials)

Phase Distribution

Ph not_applicable
1
7%
Ph phase_1
3
20%
Ph phase_2
6
40%
Ph early_phase_1
2
13%
Ph phase_4
2
13%
Ph phase_3
1
7%

Phase Distribution

5

Early Stage

6

Mid Stage

3

Late Stage

Phase Distribution15 total trials
Early Phase 1First-in-human
2(13.3%)
Phase 1Safety & dosage
3(20.0%)
Phase 2Efficacy & side effects
6(40.0%)
Phase 3Large-scale testing
1(6.7%)
Phase 4Post-market surveillance
2(13.3%)
N/ANon-phased studies
1(6.7%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

88.9%

8 of 9 finished

Non-Completion Rate

11.1%

1 ended early

Currently Active

3

trials recruiting

Total Trials

15

all time

Status Distribution
Active(4)
Completed(8)
Terminated(1)
Other(2)

Detailed Status

Completed8
Recruiting3
unknown2
Enrolling by invitation1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
15
Active
3
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (13.3%)
Phase 13 (20.0%)
Phase 26 (40.0%)
Phase 31 (6.7%)
Phase 42 (13.3%)
N/A1 (6.7%)

Trials by Status

completed853%
recruiting320%
unknown213%
enrolling_by_invitation17%
withdrawn17%

Recent Activity

3 active trials
Showing 5 of 15
recruitingphase_2

A Study of Pyridostigmine in Postural Tachycardia Syndrome

NCT00409435
recruitingphase_1

Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV

NCT04353778
recruitingphase_2

LIFT: Life Improvement Trial

NCT06366724
enrolling_by_invitationphase_2

Droxidopa / Pyridostigmine in Orthostatic Hypotension

NCT01370512
withdrawnphase_2

Clinical Usefulness and Influence on Esophageal Motility of Pyridostigmine for Dysphagia in Systemic Sclerosis

NCT06915181
View all 15 trials

Clinical Trials (15)

Showing 15 of 15 trials
NCT00409435Phase 2

A Study of Pyridostigmine in Postural Tachycardia Syndrome

Recruiting
NCT04353778Phase 1

Effects of Vagal Dysfunction on Gastrointestinal and Inflammatory Pathways in HIV

Recruiting
NCT06366724Phase 2

LIFT: Life Improvement Trial

Recruiting
NCT01370512Phase 2

Droxidopa / Pyridostigmine in Orthostatic Hypotension

Enrolling By Invitation
NCT06915181Phase 2

Clinical Usefulness and Influence on Esophageal Motility of Pyridostigmine for Dysphagia in Systemic Sclerosis

Withdrawn
NCT05969119Phase 4

Addition of Pyridostigmine to Conventional Management of Postdural Puncture Headache

Completed
NCT05919407Phase 3

Pyridostigmine and Amifampridine for Myasthenia Gravis

Unknown
NCT03261570Early Phase 1

Cardiovagal Baroreflex Deficits Impair Neurovascular Coupling and Cognition in POTS

Completed
NCT02850276Early Phase 1

Autonomic Neuropathy, GI Motility, and Inflammation in HIV

Completed
NCT03063515Phase 1

AchE Inhibitor and Insulin

Completed
NCT03510546Phase 4

Effect of Pyridostigmine (Mestinon) on Muscle Strength in Myasthenia Gravis

Unknown
NCT02941328Phase 2

SPACE Trial: Pyridostigmine vs Placebo in SMA Types 2, 3 and 4

Completed
NCT00276406Phase 1

Use of Pyridostigmine for Constipation in Diabetics

Completed
NCT00953914Not Applicable

Pyridostigmine and Its Effects on Autonomic Modulation in Diabetic Patients

Completed
NCT00535587Phase 2

Testing Mestinon and Exercise in Fibromyalgia

Completed

All 15 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
15