Success Metrics

Active Trials
8(40%)

Phase Distribution

Ph phase_1
3
15%
Ph phase_3
1
5%
Ph phase_2
16
80%

Phase Distribution

3

Early Stage

16

Mid Stage

1

Late Stage

Phase Distribution20 total trials
Phase 1Safety & dosage
3(15.0%)
Phase 2Efficacy & side effects
16(80.0%)
Phase 3Large-scale testing
1(5.0%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

0.0%

0 of 0 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

8

trials recruiting

Total Trials

20

all time

Status Distribution
Active(20)

Detailed Status

Not yet recruiting12
Recruiting8

Development Timeline

Analytics

Development Status

Total Trials
20
Active
8
Success Rate
N/A
Most Advanced
Phase 3

Trials by Phase

Phase 13 (15.0%)
Phase 216 (80.0%)
Phase 31 (5.0%)

Trials by Status

recruiting840%
not_yet_recruiting1260%

Recent Activity

Clinical Trials (20)

Showing 20 of 20 trials
NCT07518979Phase 2

EGFR-ADC (Becotatug Vedotin) Combined With PD-1 Inhibitor (Pucotenlimab) in Neoadjuvant Treatment of Advanced Penile Cancer

Recruiting
NCT07479485Phase 1

MRG006A Combination Therapy for Advanced Hepatocellular Carcinoma (Phase I/II)

Recruiting
NCT07712029Phase 2

Phase II Study of Becotatug Vedotin Plus Pucotenlimab for Advanced Refractory Solid Tumors With EGFR-Positive

Recruiting
NCT07707167Phase 2

A Prospective, Exploratory Study of Becotatug Vedotin Plus Putlimab for Neoadjuvant Therapy and Adjuvant Radiotherapy in Locally Advanced Head and Neck Squamous Cell Carcinoma

Not Yet Recruiting
NCT07692334Phase 2

Becotatugvedotin Plus Pucotenlimab in EGFR-Positive Advanced Gastric/GEJ Adenocarcinoma

Not Yet Recruiting
NCT07649980Phase 2

Becotatug Vedotin Plus Pucotenlimab for Advanced Biliary Tract Cancer, Phase II

Not Yet Recruiting
NCT07627321Phase 2

Becotatug Vedotin Combined With Pucotenlimab ± Radiotherapy as First-Line Treatment for Driver-Gene-Negative, EGFR-Expression-Positive Advanced Non-Small Cell Lung Cancer

Not Yet Recruiting
NCT07598318Phase 2

Study of Becotatug Vedotin Added to Standard Treatment for Advanced Bile Duct Cancer With EGFR Mutations

Not Yet Recruiting
NCT07589049Phase 2

Becotatug Vedotin Combined With Pucotenlimab as Neoadjuvant Therapy for Resectable Recurrent Head and Neck Squamous Cell Carcinoma After Progression on Immunotherapy: A Prospective Phase II Study

Not Yet Recruiting
NCT07448142Phase 2

Low-Dose Radiotherapy to Sensitize Pucotenlimab Plus CAPEOX for pMMR Locally Advanced Rectal Cancer

Recruiting
NCT07524413Phase 3

Becotatug Vedotin (MRG003) With PD-1 Blockade and Chemoradiotherapy in High-Risk Locoregionally Advanced Nasopharyngeal Carcinoma

Not Yet Recruiting
NCT07464366Phase 2

The Safety and Efficacy of MRG003 With or Without Putrelimab in Recurrent or Metastatic Salivary Gland Cancer: a Single-center, Open-label Cohort Study

Recruiting
NCT07394244Phase 2

Pucotenlimab Combined With Becotatug Vedotin in Advanced Cutaneous Squamous Cell Carcinoma

Not Yet Recruiting
NCT07312422Phase 1

LDRT Combined With Pucotenlimab and Standard Therapy for Advanced Pancreatic Cancer: A Single-Arm Study

Recruiting
NCT07353827Phase 2

FOLFOX-HAIC Combined With Donafenib and Pucotenlimab as First-Line Treatment for Unresectable Intrahepatic Cholangiocarcinoma

Not Yet Recruiting
NCT06770270Phase 2

Pucotenlimab Plus Radiotherapy and Chemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cance(PUCRT)

Recruiting
NCT06959108Phase 2

Clinical Trial Comparing Induction Treatment With EGFR-ADC MRG003 Alone or in Combination With the Anti PD1 Pucotenlimab, Followed by Radiochemotherapy in Locally Advanced Squamous Cell Cancers of the Head and Neck

Not Yet Recruiting
NCT06895369Phase 2

The Efficacy and Safety of Pucotenlimab Combined With TP Chemotherapy as Neoadjuvant Therapy for Locally Advanced HNSCC

Not Yet Recruiting
NCT06872606Phase 2

Short-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal Cancer

Not Yet Recruiting
NCT06456892Phase 1

Effectiveness of Pucotenlimab Combined With Standard Chemotherapy Regimen

Recruiting

All 20 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
20