Success Metrics

Clinical Success Rate
96.2%

Based on 50 completed trials

Completion Rate
96%(50/52)
Active Trials
2(3%)
Results Posted
24%(12 trials)
Terminated
2(3%)

Phase Distribution

Ph not_applicable
9
15%
Ph phase_2
7
11%
Ph phase_3
10
16%
Ph phase_4
16
26%
Ph phase_1
11
18%

Phase Distribution

11

Early Stage

7

Mid Stage

26

Late Stage

Phase Distribution53 total trials
Phase 1Safety & dosage
11(20.8%)
Phase 2Efficacy & side effects
7(13.2%)
Phase 3Large-scale testing
10(18.9%)
Phase 4Post-market surveillance
16(30.2%)
N/ANon-phased studies
9(17.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

94.3%

50 of 53 finished

Non-Completion Rate

5.7%

3 ended early

Currently Active

2

trials recruiting

Total Trials

61

all time

Status Distribution
Active(2)
Completed(50)
Terminated(3)
Other(6)

Detailed Status

Completed50
unknown5
Terminated2
Recruiting2
Suspended1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
61
Active
2
Success Rate
96.2%
Most Advanced
Phase 4

Trials by Phase

Phase 111 (20.8%)
Phase 27 (13.2%)
Phase 310 (18.9%)
Phase 416 (30.2%)
N/A9 (17.0%)

Trials by Status

terminated23%
completed5082%
suspended12%
unknown58%
withdrawn12%
recruiting23%

Recent Activity

Clinical Trials (61)

Showing 20 of 61 trialsScroll for more
NCT06666491Phase 3

An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older

Recruiting
NCT06148792Phase 3

A Revised Tafenoquine Dose to Improve Radical Cure for Vivax Malaria

Recruiting
NCT06191458Phase 4

Postpartum Primaquine in Breast Milk

Completed
NCT04706130Phase 4

Rigorous Assessment of P. Vivax Relapses and Primaquine Efficacy for Radical Cure

Completed
NCT03529396Phase 2

Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients

Completed
NCT05044637Phase 2

Study to Evaluate Primaquine for Radical Cure of Uncomplicated Plasmodium Vivax Malaria in Children

Completed
NCT06294912Phase 1

A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)

Completed
NCT04411836Phase 3

Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and Primaquine

Completed
NCT04079621Phase 4

Short Course Radical Cure of P. Vivax Malaria in Nepal

Completed
NCT04661579Phase 2

Study of Malaria Vaccine RTS,S/AS01E in Plasmodium Falciparum-infected and Uninfected Adults Pre-treated With Anti-malarial Therapy

Completed
NCT04864444Not Applicable

Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination Activities

Completed
NCT04280692Phase 1

Controlled Human Malaria Infection Transmission Model - Phase A

Suspended
NCT04666350

Clinical Investigation Study to Evaluate the Consistency and Reproducibility of Two Consecutive Mosquito Feeding Assays

Completed
NCT04984759Phase 4

Tafenoquine and Primaquine in Colostrum and Breast Milk

Withdrawn
NCT02389374Phase 4

A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east Bangladesh

Completed
NCT03916003Phase 4

Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic Areas

Completed
NCT05753150

Operational Feasibility of Appropriate Plasmodium Vivax Radical Cure After G6PD Testing in Thailand

Completed
NCT06044805Phase 4

Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium Vivax

Completed
NCT06036030Phase 2

Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West Papua

Completed
NCT05958797

TES of Chloroquine for Pv in the Philippines in 2016

Completed

Drug Details

Intervention Type
DRUG
Total Trials
61