Success Metrics

Clinical Success Rate
97.6%

Based on 41 completed trials

Completion Rate
98%(41/42)
Active Trials
2(4%)
Results Posted
80%(33 trials)
Terminated
1(2%)

Phase Distribution

Ph phase_1
6
13%
Ph phase_2
11
24%
Ph phase_4
4
9%
Ph phase_3
23
51%
Ph early_phase_1
1
2%

Phase Distribution

7

Early Stage

11

Mid Stage

27

Late Stage

Phase Distribution45 total trials
Early Phase 1First-in-human
1(2.2%)
Phase 1Safety & dosage
6(13.3%)
Phase 2Efficacy & side effects
11(24.4%)
Phase 3Large-scale testing
23(51.1%)
Phase 4Post-market surveillance
4(8.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

97.6%

41 of 42 finished

Non-Completion Rate

2.4%

1 ended early

Currently Active

2

trials recruiting

Total Trials

45

all time

Status Distribution
Active(2)
Completed(41)
Terminated(1)
Other(1)

Detailed Status

Completed41
Recruiting2
Terminated1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
45
Active
2
Success Rate
97.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.2%)
Phase 16 (13.3%)
Phase 211 (24.4%)
Phase 323 (51.1%)
Phase 44 (8.9%)

Trials by Status

terminated12%
completed4191%
recruiting24%
unknown12%

Recent Activity

Clinical Trials (45)

Showing 20 of 45 trialsScroll for more
NCT07017777Phase 3

A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infants Aged 2 Months (Minimum 6 Weeks)

Recruiting
NCT05170399Phase 4

Vaccine Responses in Patients With B Cell Malignancies

Recruiting
NCT06183216Phase 1

A Phase 1b Clinical Trial of 13-valent Pneumococcal Polysaccharide Conjugate Vaccine

Completed
NCT05412030Phase 2

A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants

Completed
NCT03819049Phase 1

A Study of Three Different Doses of VAC52416 (ExPEC10V) in Adults Aged 60 to 85 Years in Stable Health

Completed
NCT06698198Phase 1

Safety and Immunogenicity of a Pneumococcal Conjugate Vaccine Candidate in Healthy Adults (19-49 Years)

Completed
NCT03692871Phase 3

A Study to Evaluate the Safety and Tolerability of V114 and Prevnar 13™ in Healthy Infants (V114-031/PNEU-LINK)

Completed
NCT03565900Phase 3

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Allogeneic Hematopoietic Stem Cell Transplant Recipients (V114-022/PNEU-STEM)

Completed
NCT03893448Phase 3

Safety, Tolerability, and Immunogenicity of V114 in Healthy Infants (V114-029)

Completed
NCT03921424Phase 3

Safety and Immunogenicity of V114 in Children Infected With Human Immunodeficiency Virus (HIV) (V114-030/PNEU-WAY PED)

Completed
NCT03620162Phase 3

A Study to Evaluate the Interchangeability of V114 and Prevnar 13™ in Healthy Infants (V114-027/PNEU-DIRECTION)

Completed
NCT03885934Phase 3

Safety and Immunogenicity of Catch-up Vaccination Regimens of V114 (V114-024)

Completed
NCT02851056Early Phase 1

Survivin Vaccine : Multiple Myeloma Autologous Hematopoietic Cell Transplant (HCT)

Completed
NCT03480802Phase 3

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults Infected With Human Immunodeficiency Virus (HIV) (V114-018)

Completed
NCT03550313Phase 2

Study to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine Given With Prevnar 13 in Healthy Infants

Terminated
NCT02225587Phase 3

Evaluation of the Safety and Immunogenicity of Sequential Administration of Prevnar 13™ and Pneumovax™ 23 in Healthy Participants 50 Years of Age and Older (V110-029)

Completed
NCT03480763Phase 3

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Healthy Adults 50 Years of Age or Older (V114-016/PNEU-PATH)

Completed
NCT02370069Phase 4

The Effect of Previous Pneumococcal Immunization on the Immune Response of Patients With Severe CKD to Prevnar 13

Completed
NCT03731182Phase 3

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (V114-023/PNEU-SICKLE)

Completed
NCT03950622Phase 3

Safety and Immunogenicity of V114 in Healthy Adults (V114-019/PNEU-AGE)

Completed

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
45