Success Metrics

Clinical Success Rate
97.6%

Based on 41 completed trials

Completion Rate
98%(41/42)
Active Trials
2(4%)
Results Posted
80%(33 trials)
Terminated
1(2%)

Phase Distribution

Ph early_phase_1
1
2%
Ph phase_2
11
24%
Ph phase_3
23
51%
Ph phase_1
6
13%
Ph phase_4
4
9%

Phase Distribution

7

Early Stage

11

Mid Stage

27

Late Stage

Phase Distribution45 total trials
Early Phase 1First-in-human
1(2.2%)
Phase 1Safety & dosage
6(13.3%)
Phase 2Efficacy & side effects
11(24.4%)
Phase 3Large-scale testing
23(51.1%)
Phase 4Post-market surveillance
4(8.9%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

97.6%

41 of 42 finished

Non-Completion Rate

2.4%

1 ended early

Currently Active

2

trials recruiting

Total Trials

45

all time

Status Distribution
Active(2)
Completed(41)
Terminated(1)
Other(1)

Detailed Status

Completed41
Active, not recruiting1
unknown1
Recruiting1
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
45
Active
2
Success Rate
97.6%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.2%)
Phase 16 (13.3%)
Phase 211 (24.4%)
Phase 323 (51.1%)
Phase 44 (8.9%)

Trials by Status

active_not_recruiting12%
unknown12%
recruiting12%
completed4191%
terminated12%

Recent Activity

Clinical Trials (45)

Showing 20 of 45 trialsScroll for more
NCT07017777Phase 3

A Study to Evaluate the Immunogenicity and Safety of 13-valent Pneumococcal Conjugate Vaccine (PCV13i) in Healthy Infants Aged 2 Months (Minimum 6 Weeks)

Active Not Recruiting
NCT05170399Phase 4

Vaccine Responses in Patients With B Cell Malignancies

Recruiting
NCT03819049Phase 1

A Study of Three Different Doses of VAC52416 (ExPEC10V) in Adults Aged 60 to 85 Years in Stable Health

Completed
NCT06183216Phase 1

A Phase 1b Clinical Trial of 13-valent Pneumococcal Polysaccharide Conjugate Vaccine

Completed
NCT05412030Phase 2

A Phase 2 Study to Evaluate the Safety, Tolerability, and Immune Response of AFX3772 Vaccine in Healthy Infants

Completed
NCT06698198Phase 1

Safety and Immunogenicity of a Pneumococcal Conjugate Vaccine Candidate in Healthy Adults (19-49 Years)

Completed
NCT03692871Phase 3

A Study to Evaluate the Safety and Tolerability of V114 and Prevnar 13™ in Healthy Infants (V114-031/PNEU-LINK)

Completed
NCT03565900Phase 3

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Allogeneic Hematopoietic Stem Cell Transplant Recipients (V114-022/PNEU-STEM)

Completed
NCT03893448Phase 3

Safety, Tolerability, and Immunogenicity of V114 in Healthy Infants (V114-029)

Completed
NCT03921424Phase 3

Safety and Immunogenicity of V114 in Children Infected With Human Immunodeficiency Virus (HIV) (V114-030/PNEU-WAY PED)

Completed
NCT03620162Phase 3

A Study to Evaluate the Interchangeability of V114 and Prevnar 13™ in Healthy Infants (V114-027/PNEU-DIRECTION)

Completed
NCT03885934Phase 3

Safety and Immunogenicity of Catch-up Vaccination Regimens of V114 (V114-024)

Completed
NCT02851056Early Phase 1

Survivin Vaccine : Multiple Myeloma Autologous Hematopoietic Cell Transplant (HCT)

Completed
NCT03480802Phase 3

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Adults Infected With Human Immunodeficiency Virus (HIV) (V114-018)

Completed
NCT03550313Phase 2

Study to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Vaccine Given With Prevnar 13 in Healthy Infants

Terminated
NCT02225587Phase 3

Evaluation of the Safety and Immunogenicity of Sequential Administration of Prevnar 13™ and Pneumovax™ 23 in Healthy Participants 50 Years of Age and Older (V110-029)

Completed
NCT03480763Phase 3

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by PNEUMOVAX™23 in Healthy Adults 50 Years of Age or Older (V114-016/PNEU-PATH)

Completed
NCT02370069Phase 4

The Effect of Previous Pneumococcal Immunization on the Immune Response of Patients With Severe CKD to Prevnar 13

Completed
NCT03731182Phase 3

A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (V114-023/PNEU-SICKLE)

Completed
NCT03950622Phase 3

Safety and Immunogenicity of V114 in Healthy Adults (V114-019/PNEU-AGE)

Completed

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
45