Success Metrics

Clinical Success Rate
100.0%

Based on 18 completed trials

Completion Rate
100%(18/18)
Active Trials
7(26%)
Results Posted
67%(12 trials)

Phase Distribution

Ph phase_1
12
44%
Ph phase_4
1
4%
Ph phase_2
8
30%
Ph phase_3
5
19%

Phase Distribution

12

Early Stage

8

Mid Stage

6

Late Stage

Phase Distribution26 total trials
Phase 1Safety & dosage
12(46.2%)
Phase 2Efficacy & side effects
8(30.8%)
Phase 3Large-scale testing
5(19.2%)
Phase 4Post-market surveillance
1(3.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

94.7%

18 of 19 finished

Non-Completion Rate

5.3%

1 ended early

Currently Active

7

trials recruiting

Total Trials

27

all time

Status Distribution
Active(7)
Completed(18)
Terminated(1)
Other(1)

Detailed Status

Completed18
Recruiting5
Active, not recruiting2
Withdrawn1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
27
Active
7
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 112 (46.2%)
Phase 28 (30.8%)
Phase 35 (19.2%)
Phase 41 (3.8%)

Trials by Status

withdrawn14%
unknown14%
recruiting519%
active_not_recruiting27%
completed1867%

Recent Activity

Clinical Trials (27)

Showing 20 of 27 trialsScroll for more
NCT07225985Phase 1

Pralatrexate With Bendamustine and Total-Body Irradiation Followed by Donor Stem Cell Transplant for the Treatment of Relapsed or Refractory T-Cell Non-Hodgkin Lymphoma

Recruiting
NCT06561048Phase 3

Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

Recruiting
NCT04747236Phase 2

Randomized Phase IIB Trial of Oral Azacytidine Plus Romidepsin Versus Investigator's Choice in PTCL

Recruiting
NCT07234162Phase 3

A Phase 3 Multinational Study of Golidocitinib Versus Investigator's Choice in r/r PTCL (JACKPOT19)

Recruiting
NCT03240211Phase 1

Study of Pembrolizumab Combined With Decitabine and Pralatrexate in PTCL and CTCL

Active Not Recruiting
NCT03598998Phase 1

Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas

Active Not Recruiting
NCT01626664Phase 2

KW-0761 or Investigator's Choice in Subjects With Previously Treated Adult T-cell Leukemia-Lymphoma (ATL)

Completed
NCT01206465Phase 1

Pralatrexate and Fluorouracil in Treating Patients With Recurrent Solid Tumors

Completed
NCT01336933Phase 2

Combination Chemotherapy and Pralatrexate as First-Line Therapy in Treating Patients With Non-Hodgkin Lymphoma

Completed
NCT01947140Phase 1

Pralatrexate + Romidepsin in Relapsed/Refractory Lymphoid Malignancies

Completed
NCT03161223Phase 1

Durvalumab in Different Combinations With Pralatrexate, Romidepsin and Oral 5-Azacitidine for Lymphoma

Recruiting
NCT00998946Phase 2

Study of Pralatrexate to Treat Participants With Relapsed or Refractory B-cell Non-Hodgkin's Lymphoma

Completed
NCT00052442Phase 1

10-Propargyl-10-Deazaaminopterin in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma or Hodgkin's Lymphoma

Completed
NCT00606502Phase 2

Study of Pralatrexate vs. Erlotinib for Non-Small Cell Lung Cancer After at Least 1 Prior Platinum-based Treatment

Completed
NCT00554827Phase 1

Study of Pralatrexate in Patients With Relapsed or Refractory Cutaneous T-cell Lymphoma

Completed
NCT03349333Phase 3

A Single Arm Study Evaluating the Efficacy and Safety of Pralatrexate in Subjects With Relapsed or Refractory PTCL

Completed
NCT03355768Phase 3

Romidepsin Versus Combination of Romidepsin Plus Pralatrexate in PTCL

Withdrawn
NCT01482962Phase 3

Alisertib (MLN8237) or Investigator's Choice in Patients With Relapsed/Refractory Peripheral T-Cell Lymphoma

Completed
NCT01188876Phase 1

Carboplatin/Pralatrexate in Recurrent Platinum-Sensitive Ovarian, Fallopian or Primary Peritoneal Cancer

Completed
NCT01178944Phase 2

Pralatrexate and Oxaliplatin in Treating Patients With Unresectable or Metastatic Esophageal, Stomach, or Gastroesophageal Junction Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
27