Success Metrics

Clinical Success Rate
68.5%

Based on 74 completed trials

Completion Rate
69%(74/108)
Active Trials
86(37%)
Results Posted
99%(73 trials)
Terminated
34(15%)

Phase Distribution

Ph not_applicable
5
2%
Ph phase_1
98
42%
Ph phase_2
78
34%
Ph phase_4
2
1%
Ph early_phase_1
1
0%
Ph phase_3
42
18%

Phase Distribution

99

Early Stage

78

Mid Stage

44

Late Stage

Phase Distribution226 total trials
Early Phase 1First-in-human
1(0.4%)
Phase 1Safety & dosage
98(43.4%)
Phase 2Efficacy & side effects
78(34.5%)
Phase 3Large-scale testing
42(18.6%)
Phase 4Post-market surveillance
2(0.9%)
N/ANon-phased studies
5(2.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

61.2%

74 of 121 finished

Non-Completion Rate

38.8%

47 ended early

Currently Active

86

trials recruiting

Total Trials

232

all time

Status Distribution
Active(98)
Completed(74)
Terminated(47)
Other(13)

Detailed Status

Completed74
Recruiting43
Active, not recruiting43
Terminated34
unknown13
Withdrawn13

Development Timeline

Analytics

Development Status

Total Trials
232
Active
86
Success Rate
68.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (0.4%)
Phase 198 (43.4%)
Phase 278 (34.5%)
Phase 342 (18.6%)
Phase 42 (0.9%)
N/A5 (2.2%)

Trials by Status

completed7432%
enrolling_by_invitation10%
recruiting4319%
unknown136%
withdrawn136%
terminated3415%
active_not_recruiting4319%
not_yet_recruiting115%

Recent Activity

Clinical Trials (232)

Showing 20 of 232 trialsScroll for more
NCT04925193Phase 2

Personalized Selinexor-based Therapy for Relapsed/Refractory Multiple Myeloma

Active Not Recruiting
NCT05519085Phase 3

A Study to Evaluate Mezigdomide, Bortezomib and Dexamethasone (MEZIVd) Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM)

Recruiting
NCT05730036Phase 3

A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma

Recruiting
NCT06948084Phase 2

Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse

Recruiting
NCT07391657Phase 3

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

Recruiting
NCT07222761Phase 3

A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/Refractory Multiple Myeloma (RRMM)

Recruiting
NCT05288062Phase 2

Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (Dexamethasone) for the Treatment of Multiple Myeloma

Terminated
NCT05050097Phase 1

A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT04181827Phase 3

A Study Comparing JNJ-68284528, a CAR-T Therapy Directed Against B-cell Maturation Antigen (BCMA), Versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Participants With Relapsed and Lenalidomide-Refractory Multiple Myeloma

Active Not Recruiting
NCT04722146Phase 1

A Study of Teclistamab With Other Anticancer Therapies in Participants With Multiple Myeloma

Active Not Recruiting
NCT04973605Phase 1

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma

Recruiting
NCT04577755Phase 2

Pomalidomide Treatment in Patients With Kaposi Sarcoma

Active Not Recruiting
NCT05455320Phase 3

A Study Comparing Talquetamab in Combination With Daratumumab or in Combination With Daratumumab and Pomalidomide Versus Daratumumab in Combination With Pomalidomide and Dexamethasone in Participants With Multiple Myeloma That Returns After Treatment or is Resistant to Treatment

Active Not Recruiting
NCT06208150Phase 3

A Study Comparing Talquetamab Plus Pomalidomide, Talquetamab Plus Teclistamab, and Elotuzumab, Pomalidomide, and Dexamethasone or Pomalidomide, Bortezomib, and Dexamethasone in Participants With Relapsed or Refractory Myeloma Who Have Received an Anti-CD38 Antibody and Lenalidomide

Active Not Recruiting
NCT04108195Phase 1

A Study of Subcutaneous Daratumumab Regimens in Combination With Bispecific T Cell Redirection Antibodies for the Treatment of Participants With Multiple Myeloma

Active Not Recruiting
NCT01745588Phase 2

Autologous Stem Cell Transplant With Pomalidomide (CC-4047®) Maintenance Versus Continuous Clarithromycin/ Pomalidomide / Dexamethasone Salvage Therapy in Relapsed or Refractory Multiple Myeloma

Completed
NCT05083169Phase 3

A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma

Active Not Recruiting
NCT06768489Phase 1

A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide for Multiple Myeloma, Newly Diagnosed AL Amyloidosis, and High-risk Smoldering Multiple Myeloma or JNJ-79635322 in Combination With Pomalidomide for Multiple Myeloma

Recruiting
NCT05438043Phase 3

A Study of Daratumumab

Active Not Recruiting
NCT05789303Phase 2

Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
232