Success Metrics

Clinical Success Rate
71.4%

Based on 15 completed trials

Completion Rate
71%(15/21)
Active Trials
4(15%)
Results Posted
47%(7 trials)
Terminated
6(22%)

Phase Distribution

Ph phase_2
2
7%
Ph early_phase_1
1
4%
Ph phase_1
24
89%

Phase Distribution

25

Early Stage

2

Mid Stage

0

Late Stage

Phase Distribution27 total trials
Early Phase 1First-in-human
1(3.7%)
Phase 1Safety & dosage
24(88.9%)
Phase 2Efficacy & side effects
2(7.4%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

68.2%

15 of 22 finished

Non-Completion Rate

31.8%

7 ended early

Currently Active

4

trials recruiting

Total Trials

27

all time

Status Distribution
Active(5)
Completed(15)
Terminated(7)

Detailed Status

Completed15
Terminated6
Active, not recruiting3
Not yet recruiting1
Recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
27
Active
4
Success Rate
71.4%
Most Advanced
Phase 2

Trials by Phase

Early Phase 11 (3.7%)
Phase 124 (88.9%)
Phase 22 (7.4%)

Trials by Status

not_yet_recruiting14%
recruiting14%
active_not_recruiting311%
withdrawn14%
terminated622%
completed1556%

Recent Activity

Clinical Trials (27)

Showing 20 of 27 trialsScroll for more
NCT05111353Phase 1

Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery

Completed
NCT02287428Phase 1

Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM

Active Not Recruiting
NCT07300475Phase 1

Cancer Immunotherapeutic (PCI) Strategy in Triple Negative Breast Cancer Patients

Not Yet Recruiting
NCT05010200Phase 1

The Safety and Tolerability of PGV001-based Personalized Multi-peptide Vaccines in the Adjuvant Setting.

Active Not Recruiting
NCT01970358Phase 1

A Phase I Study With a Personalized NeoAntigen Cancer Vaccine in Melanoma

Completed
NCT06472661Early Phase 1

FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma

Recruiting
NCT03223103Phase 1

Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma

Active Not Recruiting
NCT01130077Phase 1

A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas

Completed
NCT04364230Phase 1

Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma)

Completed
NCT02924038Phase 1

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)

Terminated
NCT02834052Phase 1

Pembrolizumab + Poly-ICLC in MRP Colon Cancer

Completed
NCT02126579Phase 1

Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists

Completed
NCT03617328Phase 1

Vaccination With 6MHP, With or Without Systemic CDX-1127, in Patients With Stage II-IV Melanoma

Completed
NCT02425306Phase 1

Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma

Terminated
NCT02643303Phase 1

A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers

Completed
NCT01976585Phase 1

In Situ Vaccine for Low-Grade Lymphoma: Combination of Intratumoral Flt3L and Poly-ICLC With Low-Dose Radiotherapy

Completed
NCT02334735Phase 2

A Comparison of Matured Dendritic Cells and Montanide® in Study Subjects With High Risk of Melanoma Recurrence

Completed
NCT02721043Phase 1

Safety and Immunogenicity of Personalized Genomic Vaccine to Treat Malignancies

Completed
NCT01532960Phase 1

Pilot Study of a Breast Cancer Vaccine Plus Poly-ICLC for Breast Cancer

Terminated
NCT00646152Phase 1

Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study

Completed

Drug Details

Intervention Type
BIOLOGICAL
Total Trials
27