Poly-ICLC
Poly-ICLC is a biological therapy with 27 clinical trials. Currently 4 active trials ongoing. Historical success rate of 71.4%.
Success Metrics
Based on 15 completed trials
Phase Distribution
Phase Distribution
25
Early Stage
2
Mid Stage
0
Late Stage
Highest Phase Reached
Phase 2Trial Status & Enrollment
68.2%
15 of 22 finished
31.8%
7 ended early
4
trials recruiting
27
all time
Detailed Status
Development Timeline
Analytics
Development Status
Trials by Phase
Trials by Status
Recent Activity
Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
Cancer Immunotherapeutic (PCI) Strategy in Triple Negative Breast Cancer Patients
The Safety and Tolerability of PGV001-based Personalized Multi-peptide Vaccines in the Adjuvant Setting.
A Phase I Study With a Personalized NeoAntigen Cancer Vaccine in Melanoma
Clinical Trials (27)
Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery
Personalized NeoAntigen Cancer Vaccine w RT Plus Pembrolizumab for Patients With Newly Diagnosed GBM
Cancer Immunotherapeutic (PCI) Strategy in Triple Negative Breast Cancer Patients
The Safety and Tolerability of PGV001-based Personalized Multi-peptide Vaccines in the Adjuvant Setting.
A Phase I Study With a Personalized NeoAntigen Cancer Vaccine in Melanoma
FUSA With Intratumoral PolyICLC in Regionally Advanced Resectable Melanoma
Safety and Immunogenicity of Personalized Genomic Vaccine and Tumor Treating Fields (TTFields) to Treat Glioblastoma
A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas
Melanoma Vaccine Against Neoantigen and Shared Antigens by CD40 Activation and TLR Agonists In Patients With Melanoma (Including Ocular Melanoma)
A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)
Pembrolizumab + Poly-ICLC in MRP Colon Cancer
Phase I/II Trial of a Long Peptide Vaccine (LPV7) Plus TLR Agonists
Vaccination With 6MHP, With or Without Systemic CDX-1127, in Patients With Stage II-IV Melanoma
Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of Melanoma
A Study of Tremelimumab and IV Durvalumab Plus Poly-ICLC in Subjects With Biopsy-accessible Cancers
In Situ Vaccine for Low-Grade Lymphoma: Combination of Intratumoral Flt3L and Poly-ICLC With Low-Dose Radiotherapy
A Comparison of Matured Dendritic Cells and Montanide® in Study Subjects With High Risk of Melanoma Recurrence
Safety and Immunogenicity of Personalized Genomic Vaccine to Treat Malignancies
Pilot Study of a Breast Cancer Vaccine Plus Poly-ICLC for Breast Cancer
Poly-ICLC to Prevent Respiratory Viral Infections A Safety Study
Drug Details
- Intervention Type
- BIOLOGICAL
- Total Trials
- 27