Success Metrics

Clinical Success Rate
76.7%

Based on 56 completed trials

Completion Rate
77%(56/73)
Active Trials
14(14%)
Results Posted
59%(33 trials)
Terminated
17(17%)

Phase Distribution

Ph phase_4
1
1%
Ph phase_1
50
51%
Ph phase_3
3
3%
Ph phase_2
34
35%
Ph early_phase_1
1
1%
Ph not_applicable
3
3%

Phase Distribution

51

Early Stage

34

Mid Stage

4

Late Stage

Phase Distribution92 total trials
Early Phase 1First-in-human
1(1.1%)
Phase 1Safety & dosage
50(54.3%)
Phase 2Efficacy & side effects
34(37.0%)
Phase 3Large-scale testing
3(3.3%)
Phase 4Post-market surveillance
1(1.1%)
N/ANon-phased studies
3(3.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.7%

56 of 77 finished

Non-Completion Rate

27.3%

21 ended early

Currently Active

14

trials recruiting

Total Trials

98

all time

Status Distribution
Active(15)
Completed(56)
Terminated(21)
Other(6)

Detailed Status

Completed56
Terminated17
Recruiting10
unknown6
Withdrawn4
Active, not recruiting4

Development Timeline

Analytics

Development Status

Total Trials
98
Active
14
Success Rate
76.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (1.1%)
Phase 150 (54.3%)
Phase 234 (37.0%)
Phase 33 (3.3%)
Phase 41 (1.1%)
N/A3 (3.3%)

Trials by Status

withdrawn44%
recruiting1010%
active_not_recruiting44%
enrolling_by_invitation11%
completed5657%
terminated1717%
unknown66%

Recent Activity

Clinical Trials (98)

Showing 20 of 98 trialsScroll for more
NCT06506461Phase 1

Gene Editing For Sickle Cell Disease

Recruiting
NCT01318317Phase 1

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

Active Not Recruiting
NCT02015013Phase 2

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Recruiting
NCT05470491Phase 1

Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Allogeneic Hematopoietic Cell Bone Marrow Transplantation Followed by Graft-versus-Host-Disease (GVHD) Prophylaxis With Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies ...

Recruiting
NCT06158828Phase 1

Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML

Recruiting
NCT05088356Phase 1

Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft

Recruiting
NCT06325709Phase 1

Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease

Recruiting
NCT05357482Phase 1

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Active Not Recruiting
NCT06207799Phase 2

Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma

Recruiting
NCT06851767Phase 1

Base-Edited Hematopoietic Stem/Progenitor Cell X-Linked Severe Combined Immunodeficiency Gene Therapy

Enrolling By Invitation
NCT06414889Phase 1

Protocol Title: Safety and Feasibility of Autologous CD34+ Hematopoietic Stem Cells Mobilization and Apheresis in Participants With RUNX1 Familial Platelet Disorder

Recruiting
NCT07188090Phase 2

Mozobil for Autologous Hematopoietic Stem Cell Transplantation

Recruiting
NCT02570542Phase 2

Study of the Impact of CD34+ Cell Dose on Absolute Lymphocyte Count Following High-Dose Therapy and Autologous Stem Cell Transplantation for Relapsed and Refractory Diffuse Large B-cell Lymphoma (DLBCL)

Active Not Recruiting
NCT03746080Phase 2

Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma

Completed
NCT05343572Early Phase 1

Bone Marrow Derived Stem Cells Mobilization for Treatment of Abnormal Endometrium

Recruiting
NCT01526096Phase 1

Stem Cell Transplantation for Patients With Multiple Myeloma

Completed
NCT03664830Phase 1

Safety of Blood Stem Cell Mobilization With Plerixafor in Patients With Sickle Cell Disease

Active Not Recruiting
NCT03653247Phase 1

A Study to Assess the Safety, Tolerability, and Efficacy of BIVV003 for Autologous Hematopoietic Stem Cell Transplantation in Patients With Severe Sickle Cell Disease

Completed
NCT02678533Phase 1

Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and Plerixafor

Completed
NCT02212535Phase 1

Assessment of Tolerance of Mobilizing Peripheral Hematopoietic Stem Cells by Plerixafor in Sickle Cell Patients

Completed

Drug Details

Intervention Type
DRUG
Total Trials
98