Success Metrics

Clinical Success Rate
72.7%

Based on 8 completed trials

Completion Rate
73%(8/11)
Active Trials
0(0%)
Results Posted
88%(7 trials)
Terminated
3(25%)

Phase Distribution

Ph phase_1
4
33%
Ph phase_2
4
33%
Ph phase_3
2
17%
Ph phase_4
1
8%
Ph early_phase_1
1
8%

Phase Distribution

5

Early Stage

4

Mid Stage

3

Late Stage

Phase Distribution12 total trials
Early Phase 1First-in-human
1(8.3%)
Phase 1Safety & dosage
4(33.3%)
Phase 2Efficacy & side effects
4(33.3%)
Phase 3Large-scale testing
2(16.7%)
Phase 4Post-market surveillance
1(8.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

66.7%

8 of 12 finished

Non-Completion Rate

33.3%

4 ended early

Currently Active

0

trials recruiting

Total Trials

12

all time

Status Distribution
Completed(8)
Terminated(4)

Detailed Status

Completed8
Terminated3
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
12
Active
0
Success Rate
72.7%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (8.3%)
Phase 14 (33.3%)
Phase 24 (33.3%)
Phase 32 (16.7%)
Phase 41 (8.3%)

Trials by Status

withdrawn18%
completed867%
terminated325%

Recent Activity

Clinical Trials (12)

Showing 12 of 12 trials
NCT00099021Phase 2

Pioglitazone Hydrochloride in Preventing Head and Neck Cancer in Patients With Oral Leukoplakia

Completed
NCT01352182Phase 1

Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock

Completed
NCT00867126Early Phase 1

Pioglitazone as Second-Line in Patients With Metastatic Pancreatic Cancer After Treatment With Gemcitabine

Terminated
NCT03457597Phase 1

Study in Healthy Subjects to Determine the Effect of Relacorilant on Exposure to Probe Substrates for Cytochrome P450s

Completed
NCT01342770Phase 2

Pioglitazone Hydrochloride in Treating Patients With Stage IA-IIIA Non-small Cell Lung Cancer

Terminated
NCT00604578Phase 2

Pioglitazone Hydrochloride (Actos(Registered Trademark)) to Treat Asthma

Withdrawn
NCT00722371Phase 3

MK0431 and Pioglitazone Co-Administration Factorial Study in Patients With Type 2 Diabetes Mellitus (0431-102 AM2)

Completed
NCT00951379Phase 2

Pioglitazone for Oral Premalignant Lesions

Terminated
NCT02473627Phase 1

A PHASE 1, OPEN-LABEL, CROSS-OVER, FIXED SEQUENCE STUDY TO EVALUATE THE EFFECT OF MULTIPLE DOSES OF DS-1971A ON THE SINGLE DOSE PHARMACOKINETICS OF PROBE SUBSTRATES FOR CYP2B6, CYP2C8, CYP2C9, CYP2C19 AND CYP3A4 ENZYMES IN HEALTHY MALE AND FEMALE SUBJECTS

Completed
NCT01589445Phase 4

Efficacy Study of Pioglitazone and Metformin and Association Between Pioglitazone Response and Peroxisome Proliferator-activated Receptor Gamma Gene Variants in Bangladeshi Type 2 Diabetes Mellitus Subjects

Completed
NCT00680745Phase 3

Efficacy and Safety of Dapagliflozin in Combination With Glimepiride (a Sulphonylurea) in Type 2 Diabetes Patients

Completed
NCT01088919Phase 1

A Study to Characterize the Effect on the Pharmacokinetics of ASP1941 and Pioglitazone Hydrochloride When Given Together to Healthy Subjects

Completed

All 12 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
12