Success Metrics

Clinical Success Rate
78.4%

Based on 29 completed trials

Completion Rate
78%(29/37)
Active Trials
3(7%)
Results Posted
28%(8 trials)
Terminated
8(18%)

Phase Distribution

Ph phase_2
6
14%
Ph phase_3
2
5%
Ph not_applicable
6
14%
Ph phase_4
9
20%
Ph early_phase_1
1
2%
Ph phase_1
18
41%

Phase Distribution

19

Early Stage

6

Mid Stage

11

Late Stage

Phase Distribution42 total trials
Early Phase 1First-in-human
1(2.4%)
Phase 1Safety & dosage
18(42.9%)
Phase 2Efficacy & side effects
6(14.3%)
Phase 3Large-scale testing
2(4.8%)
Phase 4Post-market surveillance
9(21.4%)
N/ANon-phased studies
6(14.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.3%

29 of 38 finished

Non-Completion Rate

23.7%

9 ended early

Currently Active

3

trials recruiting

Total Trials

44

all time

Status Distribution
Active(3)
Completed(29)
Terminated(9)
Other(3)

Detailed Status

Completed29
Terminated8
Recruiting3
unknown3
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
44
Active
3
Success Rate
78.4%
Most Advanced
Phase 4

Trials by Phase

Early Phase 11 (2.4%)
Phase 118 (42.9%)
Phase 26 (14.3%)
Phase 32 (4.8%)
Phase 49 (21.4%)
N/A6 (14.3%)

Trials by Status

recruiting37%
unknown37%
terminated818%
withdrawn12%
completed2966%

Recent Activity

3 active trials
Showing 5 of 44
recruitingnot_applicable

Determinants of Warfarin Metabolism

NCT00162474
completedphase_1

A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults

NCT07066722
completedphase_1

A Study of the Effect of Itraconazole and Phenytoin on Calderasib (MK-1084) in Healthy Adults (MK-1084-008)

NCT06719557
completedphase_1

Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants

NCT06906809
completed

Population Pharmacokinetics of Antiepileptic in Pediatrics

NCT03196466
View all 44 trials

Clinical Trials (44)

Showing 20 of 44 trialsScroll for more
NCT00162474Not Applicable

Determinants of Warfarin Metabolism

Recruiting
NCT07066722Phase 1

A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults

Completed
NCT06719557Phase 1

A Study of the Effect of Itraconazole and Phenytoin on Calderasib (MK-1084) in Healthy Adults (MK-1084-008)

Completed
NCT06906809Phase 1

Effect of Phenytoin or Itraconazole on How BGB-16673 is Absorbed and Removed From the Body in Healthy Participants

Completed
NCT03196466

Population Pharmacokinetics of Antiepileptic in Pediatrics

Completed
NCT06919991Phase 1

Drug-Drug Interaction Study of Casdatifan in Healthy Adult Participants (ARC-29)

Completed
NCT07072624Phase 4

Early Post-Traumatic Seizures Prevention Trial (E-PTS Trial)

Recruiting
NCT06903715Phase 1

A Clinical Study of Belzutifan (MK-6482) Alone or With Phenytoin in Healthy Participants (CA46602/MK-6482-035)

Completed
NCT06543043Phase 1

A Study to Evaluate the Effects of Phenytoin and Itraconazole on Sonrotoclax (BGB-11417) in Healthy Volunteers

Completed
NCT04845646Phase 1

DDI Study of ASC41 in HV and the PK, Safety and Tolerability in Subjects With NAFLD.

Completed
NCT05901714Phase 1

A Study to Assess the Effect of Phenytoin on the Drug Levels of Afimetoran and the Effect of Afimetoran on the Drug Levels of Midazolam

Completed
NCT05637086Phase 2

Clinical Study Evaluating Safety of Pentoxifylline and Celecoxib in Patients With Grand-Mal Epilepsy Treated by Phenytoin Monotherapy

Recruiting
NCT05995249Phase 1

A Study of the Interaction of TAK-279 With Substances That Have an Impact on Metabolism in Healthy Adults

Completed
NCT06067412Not Applicable

Efficacy of Phenytoin vs Levetiracetam in Status Epilepticus at Institute of Child Health,Faisalabad

Completed
NCT01478035Phase 4

Study on the Efficacy of Phenytoin in the Prophylaxis of Seizures of Patients With Pneumococcal Meningitis at Least 50 Yrs Old.

Terminated
NCT05697614Phase 4

The Benefit and Safety of Older Generation Anti-Epileptic Drugs (AEDs) in Drug-Resistant Epilepsy Children

Unknown
NCT01730313Phase 2

Treatment of Nodding Syndrome - A Randomized Blinded Placebo-Controlled Crossover Trial of Oral Pyridoxine and Conventional Anti-Epileptic Therapy, in Northern Uganda - 2012

Withdrawn
NCT03632915

Pharmacokinetics of Antiepileptics in Patients on CRRT

Completed
NCT04981704Phase 1

A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants

Completed
NCT00581893Phase 4

Phenytoin and Driving Safety: A Randomized, Controlled Cross-Over Study

Completed

Drug Details

Intervention Type
DRUG
Total Trials
44