Success Metrics

Clinical Success Rate
79.9%

Based on 615 completed trials

Completion Rate
80%(615/770)
Active Trials
75(8%)
Results Posted
49%(300 trials)
Terminated
155(17%)

Phase Distribution

Ph phase_3
20
2%
Ph early_phase_1
4
0%
Ph phase_2
237
26%
Ph phase_4
1
0%
Ph not_applicable
36
4%
Ph phase_1
600
65%

Phase Distribution

604

Early Stage

237

Mid Stage

21

Late Stage

Phase Distribution898 total trials
Early Phase 1First-in-human
4(0.4%)
Phase 1Safety & dosage
600(66.8%)
Phase 2Efficacy & side effects
237(26.4%)
Phase 3Large-scale testing
20(2.2%)
Phase 4Post-market surveillance
1(0.1%)
N/ANon-phased studies
36(4.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.1%

615 of 819 finished

Non-Completion Rate

24.9%

204 ended early

Currently Active

75

trials recruiting

Total Trials

920

all time

Status Distribution
Active(75)
Completed(615)
Terminated(204)
Other(26)

Detailed Status

Completed615
Terminated155
Active, not recruiting75
Withdrawn49
unknown26

Development Timeline

Analytics

Development Status

Total Trials
920
Active
75
Success Rate
79.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.4%)
Phase 1600 (66.8%)
Phase 2237 (26.4%)
Phase 320 (2.2%)
Phase 41 (0.1%)
N/A36 (4.0%)

Trials by Status

terminated15517%
active_not_recruiting758%
completed61567%
unknown263%
withdrawn495%

Recent Activity

Clinical Trials (920)

Showing 20 of 920 trialsScroll for more
NCT00268385Phase 1

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

Active Not Recruiting
NCT01012817Phase 1

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

Active Not Recruiting
NCT02446600Phase 3

Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Active Not Recruiting
NCT01142388Phase 2

Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer

Active Not Recruiting
NCT02595879Phase 1

Triapine With Chemotherapy and Radiation Therapy in Treating Patients With IB2-IVA Cervical or Vaginal Cancer

Active Not Recruiting
NCT02627443Phase 1

Carboplatin, Gemcitabine Hydrochloride, and Berzosertib in Treating Patients With Recurrent and Metastatic Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Active Not Recruiting
NCT01366144Phase 1

Veliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney Dysfunction

Active Not Recruiting
NCT02101775Phase 2

Gemcitabine Hydrochloride With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Active Not Recruiting
NCT02453620Phase 1

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Active Not Recruiting
NCT02166463Phase 3

Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Active Not Recruiting
NCT02101853Phase 3

Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia

Active Not Recruiting
NCT03244384Phase 3

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

Active Not Recruiting
NCT02142803Phase 1

TORC1/2 Inhibitor MLN0128 and Bevacizumab in Treating Patients With Recurrent Glioblastoma or Advanced Solid Tumors

Active Not Recruiting
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT01479842Phase 1

Rituxan/Bendamustine/PCI-32765 in Relapsed DLBCL, MCL, or Indolent Non-Hodgkin's Lymphoma

Active Not Recruiting
NCT01591356Phase 1

EphA2 siRNA in Treating Patients With Advanced or Recurrent Solid Tumors

Active Not Recruiting
NCT02867592Phase 2

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Active Not Recruiting
NCT03120624Phase 1

VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer

Active Not Recruiting
NCT02530034Phase 1

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

Active Not Recruiting
NCT03213652Phase 2

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting

Drug Details

Intervention Type
OTHER
Total Trials
920