Success Metrics

Clinical Success Rate
79.9%

Based on 616 completed trials

Completion Rate
80%(616/771)
Active Trials
74(8%)
Results Posted
49%(302 trials)
Terminated
155(17%)

Phase Distribution

Ph not_applicable
36
4%
Ph phase_4
1
0%
Ph early_phase_1
4
0%
Ph phase_1
600
65%
Ph phase_3
20
2%
Ph phase_2
237
26%

Phase Distribution

604

Early Stage

237

Mid Stage

21

Late Stage

Phase Distribution898 total trials
Early Phase 1First-in-human
4(0.4%)
Phase 1Safety & dosage
600(66.8%)
Phase 2Efficacy & side effects
237(26.4%)
Phase 3Large-scale testing
20(2.2%)
Phase 4Post-market surveillance
1(0.1%)
N/ANon-phased studies
36(4.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.1%

616 of 820 finished

Non-Completion Rate

24.9%

204 ended early

Currently Active

74

trials recruiting

Total Trials

920

all time

Status Distribution
Active(74)
Completed(616)
Terminated(204)
Other(26)

Detailed Status

Completed616
Terminated155
Active, not recruiting74
Withdrawn49
unknown26

Development Timeline

Analytics

Development Status

Total Trials
920
Active
74
Success Rate
79.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.4%)
Phase 1600 (66.8%)
Phase 2237 (26.4%)
Phase 320 (2.2%)
Phase 41 (0.1%)
N/A36 (4.0%)

Trials by Status

completed61667%
unknown263%
terminated15517%
active_not_recruiting748%
withdrawn495%

Recent Activity

Clinical Trials (920)

Showing 20 of 920 trialsScroll for more
NCT02166463Phase 3

Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Active Not Recruiting
NCT03244384Phase 3

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

Active Not Recruiting
NCT02996825Phase 1

Mirvetuximab Soravtansine and Gemcitabine Hydrochloride in Treating Patients With FRalpha-Positive Recurrent Ovarian, Primary Peritoneal, Fallopian Tube, Endometrial, or Triple Negative Breast Cancer

Completed
NCT02446600Phase 3

Testing the Use of A Single Drug (Olaparib) or the Combination of Two Drugs (Cediranib and Olaparib) Compared to the Usual Chemotherapy for Women With Platinum Sensitive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Active Not Recruiting
NCT02015117Phase 1

Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Active Not Recruiting
NCT02293954Not Applicable

Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive Cancer

Active Not Recruiting
NCT03210714Phase 2

Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial)

Active Not Recruiting
NCT02530034Phase 1

Hu8F4 in Treating Patients With Advanced Hematologic Malignancies

Active Not Recruiting
NCT00541073Phase 2

Pemetrexed, Cisplatin, and Vitamin B12 in Treating Patients With Mesothelioma of the Chest That Cannot Be Removed by Surgery

Completed
NCT02453620Phase 1

Entinostat, Nivolumab, and Ipilimumab in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery or Locally Advanced or Metastatic HER2-Negative Breast Cancer

Active Not Recruiting
NCT02381561Phase 1

Ropidoxuridine in Treating Patients With Advanced Gastrointestinal Cancer Undergoing Radiation Therapy

Active Not Recruiting
NCT02522715Phase 1

Enzalutamide and Cabazitaxel in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer

Active Not Recruiting
NCT01303341Phase 1

Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma

Active Not Recruiting
NCT01012817Phase 1

Veliparib and Topotecan Hydrochloride in Treating Patients With Solid Tumors, Relapsed or Refractory Ovarian Cancer, or Primary Peritoneal Cancer

Active Not Recruiting
NCT03074513Phase 2

Atezolizumab and Bevacizumab in Treating Patients With Rare Solid Tumors

Active Not Recruiting
NCT01375829Phase 1

Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Active Not Recruiting
NCT01861314Phase 1

Bortezomib, Sorafenib Tosylate, and Decitabine in Treating Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT02101775Phase 2

Gemcitabine Hydrochloride With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Active Not Recruiting
NCT01142388Phase 2

Paclitaxel With or Without Cixutumumab as Second-Line Therapy in Treating Patients With Metastatic Esophageal Cancer or Gastroesophageal Junction Cancer

Active Not Recruiting
NCT01364051Phase 1

Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies

Active Not Recruiting

Drug Details

Intervention Type
OTHER
Total Trials
920