Success Metrics

Clinical Success Rate
79.9%

Based on 610 completed trials

Completion Rate
80%(610/763)
Active Trials
82(9%)
Results Posted
49%(297 trials)
Terminated
153(17%)

Phase Distribution

Ph not_applicable
36
4%
Ph phase_1
600
65%
Ph phase_2
237
26%
Ph phase_3
20
2%
Ph phase_4
1
0%
Ph early_phase_1
4
0%

Phase Distribution

604

Early Stage

237

Mid Stage

21

Late Stage

Phase Distribution898 total trials
Early Phase 1First-in-human
4(0.4%)
Phase 1Safety & dosage
600(66.8%)
Phase 2Efficacy & side effects
237(26.4%)
Phase 3Large-scale testing
20(2.2%)
Phase 4Post-market surveillance
1(0.1%)
N/ANon-phased studies
36(4.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.1%

610 of 812 finished

Non-Completion Rate

24.9%

202 ended early

Currently Active

82

trials recruiting

Total Trials

920

all time

Status Distribution
Active(82)
Completed(610)
Terminated(202)
Other(26)

Detailed Status

Completed610
Terminated153
Active, not recruiting82
Withdrawn49
unknown26

Development Timeline

Analytics

Development Status

Total Trials
920
Active
82
Success Rate
79.9%
Most Advanced
Phase 4

Trials by Phase

Early Phase 14 (0.4%)
Phase 1600 (66.8%)
Phase 2237 (26.4%)
Phase 320 (2.2%)
Phase 41 (0.1%)
N/A36 (4.0%)

Trials by Status

completed61066%
unknown263%
active_not_recruiting829%
withdrawn495%
terminated15317%

Recent Activity

Clinical Trials (920)

Showing 20 of 920 trialsScroll for more
NCT02250937Phase 2

Venetoclax and Sequential Busulfan, Cladribine, and Fludarabine Phosphate Before Donor Stem Cell Transplant in Treating Patients With Acute Myelogenous Leukemia or Myelodysplastic Syndrome

Active Not Recruiting
NCT00295919Phase 1

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma

Completed
NCT03155620Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Active Not Recruiting
NCT00646230Phase 1

N2004-03: Intravenous Fenretinide in Treating Young Patients With Recurrent or Resistant Neuroblastoma

Completed
NCT01375829Phase 1

Ixabepilone and Temsirolimus in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery

Active Not Recruiting
NCT00392353Phase 1

Vorinostat and Azacitidine in Treating Patients With Myelodysplastic Syndromes or Acute Myeloid Leukemia

Active Not Recruiting
NCT02015117Phase 1

Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases

Active Not Recruiting
NCT01627041Phase 2

Decitabine, Cytarabine, and Daunorubicin Hydrochloride in Treating Patients With Acute Myeloid Leukemia

Active Not Recruiting
NCT02503722Phase 1

Testing the Combination of MLN0128 (TAK-228) and AZD9291 in Advanced EGFR (Epidermal Growth Factor Receptor) Mutation Positive Non-small Cell Lung Cancer

Active Not Recruiting
NCT01303341Phase 1

Riluzole and Sorafenib Tosylate in Treating Patients With Advanced Solid Tumors or Melanoma

Active Not Recruiting
NCT00268385Phase 1

Vorinostat and Temozolomide in Treating Patients With Malignant Gliomas

Active Not Recruiting
NCT03244384Phase 3

Testing MK-3475 (Pembrolizumab) After Surgery for Localized Muscle-Invasive Bladder Cancer and Locally Advanced Urothelial Cancer

Active Not Recruiting
NCT02311933Phase 2

Tamoxifen Citrate or Z-Endoxifen Hydrochloride in Treating Patients With Locally Advanced or Metastatic, Estrogen Receptor-Positive, HER2-Negative Breast Cancer

Active Not Recruiting
NCT02867592Phase 2

Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare Tumors

Active Not Recruiting
NCT03220022Phase 1

Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell Lymphomas

Active Not Recruiting
NCT02166463Phase 3

Brentuximab Vedotin and Combination Chemotherapy in Treating Children and Young Adults With Stage IIB, Stage IIIB, IVA, or IVB Hodgkin Lymphoma

Active Not Recruiting
NCT01711554Phase 1

Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma

Active Not Recruiting
NCT00336063Phase 1

Vorinostat and Azacitidine in Treating Patients With Locally Recurrent or Metastatic Nasopharyngeal Cancer or Nasal Natural Killer T-Cell Lymphoma

Active Not Recruiting
NCT02159755Phase 1

Ibrutinib and Palbociclib in Treating Patients With Previously Treated Mantle Cell Lymphoma

Active Not Recruiting
NCT01364051Phase 1

Cediranib Maleate and Selumetinib Sulfate in Treating Patients With Solid Malignancies

Active Not Recruiting

Drug Details

Intervention Type
OTHER
Total Trials
920