Biological
PfSPZ Challenge (NF54)
PfSPZ Challenge (NF54) is a biological therapy with 5 clinical trials. Currently 1 active trials ongoing. Historical success rate of 100.0%.
Total Trials
5
Max Phase
—
Type
BIOLOGICAL
Molecule
—
Success Metrics
Clinical Success Rate
100.0%
Based on 2 completed trials
Completion Rate
100%(2/2)
Active Trials
1(20%)
Results Posted
0%(0 trials)
Phase Distribution
Ph phase_1
5
100%
Phase Distribution
5
Early Stage
0
Mid Stage
0
Late Stage
Phase Distribution5 total trials
Phase 1Safety & dosage
5(100.0%)
Highest Phase Reached
Phase 1Trial Status & Enrollment
Completion Rate
100.0%
2 of 2 finished
Non-Completion Rate
0.0%
0 ended early
Currently Active
1
trials recruiting
Total Trials
5
all time
Status Distribution
Active(3)
Completed(2)
Detailed Status
Not yet recruiting2
Completed2
Recruiting1
Development Timeline
Analytics
Development Status
Total Trials
5
Active
1
Success Rate
100.0%
Most Advanced
Phase 1
Trials by Phase
Phase 15 (100.0%)
Trials by Status
not_yet_recruiting240%
recruiting120%
completed240%
Recent Activity
1 active trials
Showing 5 of 5
not_yet_recruitingphase_1
Malaria CVD 36000; Gates INV090205
NCT07558122
recruitingphase_1
Safety, Tolerability and Efficacy Against Controlled Human Malaria Infection of PfSPZ-LARC2 Vaccine in Malaria-naïve Adults
NCT06862453
not_yet_recruitingphase_1
Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults
NCT05441410
completedphase_1
Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis
NCT02858817
completedphase_1
Sequential Optimization of Dose and Schedule of PfSPZ Vaccine
NCT02704533
Clinical Trials (5)
Showing 5 of 5 trials
NCT07558122Phase 1
Malaria CVD 36000; Gates INV090205
NCT06862453Phase 1
Safety, Tolerability and Efficacy Against Controlled Human Malaria Infection of PfSPZ-LARC2 Vaccine in Malaria-naïve Adults
NCT05441410Phase 1
Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults
NCT02858817Phase 1
Safety and Protective Efficacy of IV Immunization With Cryopreserved PfSPZ Under A/P Chemoprophylaxis
NCT02704533Phase 1
Sequential Optimization of Dose and Schedule of PfSPZ Vaccine
All 5 trials loaded
Drug Details
- Intervention Type
- BIOLOGICAL
- Total Trials
- 5