Success Metrics

Clinical Success Rate
94.1%

Based on 16 completed trials

Completion Rate
94%(16/17)
Active Trials
0(0%)
Results Posted
38%(6 trials)
Terminated
1(6%)

Phase Distribution

Ph phase_3
1
6%
Ph phase_2
2
12%
Ph phase_1
14
82%

Phase Distribution

14

Early Stage

2

Mid Stage

1

Late Stage

Phase Distribution17 total trials
Phase 1Safety & dosage
14(82.4%)
Phase 2Efficacy & side effects
2(11.8%)
Phase 3Large-scale testing
1(5.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

94.1%

16 of 17 finished

Non-Completion Rate

5.9%

1 ended early

Currently Active

0

trials recruiting

Total Trials

17

all time

Status Distribution
Completed(16)
Terminated(1)

Detailed Status

Completed16
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
17
Active
0
Success Rate
94.1%
Most Advanced
Phase 3

Trials by Phase

Phase 114 (82.4%)
Phase 22 (11.8%)
Phase 31 (5.9%)

Trials by Status

terminated16%
completed1694%

Recent Activity

Clinical Trials (17)

Showing 17 of 17 trials
NCT03796676Phase 3

JAK1 Inhibitor With Medicated Topical Therapy in Adolescents With Atopic Dermatitis

Completed
NCT03660241Phase 1

A Renal Impairment Study for PF-04965842

Completed
NCT03626415Phase 1

A Hepatic Impairment Study for PF-04965842.

Completed
NCT03662516Phase 1

A Study to Determine the Effects of PF-04965842 on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Subjects

Completed
NCT03647670Phase 1

A Study to Determine the Effects of PF-04965842 on Midazolam PK in Healthy Volunteers

Completed
NCT03742336Phase 1

Study of PF-04965842 Effect on Dabigatran Pharmacokinetics in Healthy Participants

Completed
NCT03637790Phase 1

Drug Interaction Study Evaluating the Effect of Rifampin on PK and Safety of PF 04965842.

Completed
NCT03796182Phase 1

Study of PF 04965842 Effect on MATE1/2K Activity in Healthy Participants

Completed
NCT04099563Phase 1

Study to Assess Pharmacokinetics, Safety and Tolerability of PF-04965842 in Chinese Healthy Participants

Completed
NCT03937258Phase 1

A Study to Assess Pharmacokinetics of PF-04965842 and Its Metabolites and Effect of Probenecid in Healthy Participants

Completed
NCT03386279Phase 1

A Study To Determine The Effect Of Single-dose PF-04965842 On QTc Interval In Healthy Volunteers Compared With Placebo and Moxifloxacin

Completed
NCT03806101Phase 1

Study of PF-04965842 Effect on Rosuvastatin Pharmacokinetics in Healthy Participants

Completed
NCT02780167Phase 2

Study To Evaluate Pf-04965842 In Subjects With Moderate To Severe Atopic Dermatitis

Completed
NCT03250039Phase 1

Absorption, Metabolism, Excretion and Absolute Bioavailability

Completed
NCT02201524Phase 2

Study to Evaluate PF-04965842 in Patients With Moderate to Severe Psoriasis

Terminated
NCT02163161Phase 1

AStudy to Evaluate the Bioavailability of PF 04965842 in Healthy Subjects

Completed
NCT01835197Phase 1

First-in-Human Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of Janus Kinase-1 Inhibitor PF-04965842 in Healthy Western and Japanese Subjects

Completed

All 17 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
17