Success Metrics

Clinical Success Rate
50.0%

Based on 1 completed trials

Completion Rate
50%(1/2)
Active Trials
6(32%)
Results Posted
0%(0 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_2
12
63%
Ph phase_1
3
16%
Ph phase_3
3
16%

Phase Distribution

3

Early Stage

12

Mid Stage

3

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
3(16.7%)
Phase 2Efficacy & side effects
12(66.7%)
Phase 3Large-scale testing
3(16.7%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

50.0%

1 of 2 finished

Non-Completion Rate

50.0%

1 ended early

Currently Active

6

trials recruiting

Total Trials

19

all time

Status Distribution
Active(10)
Completed(1)
Terminated(1)
Other(7)

Detailed Status

unknown7
Recruiting5
Not yet recruiting4
Active, not recruiting1
Terminated1
Completed1

Development Timeline

Analytics

Development Status

Total Trials
19
Active
6
Success Rate
50.0%
Most Advanced
Phase 3

Trials by Phase

Phase 13 (16.7%)
Phase 212 (66.7%)
Phase 33 (16.7%)

Trials by Status

not_yet_recruiting421%
unknown737%
active_not_recruiting15%
terminated15%
completed15%
recruiting526%

Recent Activity

Clinical Trials (19)

Showing 19 of 19 trials
NCT05576480Phase 2

SCRT Sequential Penpulimab in Combination With CAPEOX in the Neoadjuvant Treatment of MSS Locally Advanced Rectal Cancer

Recruiting
NCT07075419Phase 1

JDB153 Combined With Penpulimab for Hepatocellular Carcinoma After Standard Treatment Failure

Not Yet Recruiting
NCT06943820Phase 1

AK129 Combination Therapy for Advanced Solid Tumors

Recruiting
NCT04974398Phase 3

A Study of Penpulimab (AK105) in the First-line Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma

Active Not Recruiting
NCT06297642Phase 1

TQB2928 Injection Combined With Penpulimab in Treatment of Advanced Malignant Tumors.

Terminated
NCT06516978Phase 2

A Study Comparing the Efficacy and Safety of Pola-RCHP-X Versus RCHOP-X and Pola-RCHP in Previously Untreated Patients With DLBCL

Not Yet Recruiting
NCT05229003Phase 2

Irinotecan Plus Anlotinib or Further in Combination With Penpulimab for Second-line Treatment of mCRC

Recruiting
NCT05493995Phase 2

A Study of Penpulimab and Anlotinib Plus Nab-paclitaxel and Gemcitabine for Metastatic Pancreatic Cancer.

Completed
NCT05028504Phase 2

A Phase II Study of Anlotinib Combined With Penpulimab in Subjects With Gynecological Cancer

Unknown
NCT06051851Phase 2

Penpulimab Combined With Anlotinib and Nab-paclitaxel Plus Gemcitabine as First-line Treatment for Advanced Metastatic Pancreatic Cancer

Recruiting
NCT06048315Phase 3

A Single Center, Single Arm Clinical Study on the Treatment of Advanced Non-small Cell Lung Cancer With Positive EGFR Sensitive Mutations and Failed EGFR TKIs With the Combination of Enrotinib and Paclitaxel Monoclonal Antibody

Not Yet Recruiting
NCT05885399Phase 2

The Efficacy and Safety of Penpulimab in the Treatment of Metastatic PPGL Patients Who Fail to Other Systemic Treatment

Unknown
NCT05726175Phase 2

Disitamab Vedotin(RC48) Combined With Penpulimab(AK105) for Neoadjuvant Treatment of HER2-low Breast Cancer

Unknown
NCT05680038

Penpulimab in Maintenance Therapy in Lymphoma

Unknown
NCT05485350Phase 2

Anlotinib , Penpulimab Combined With SBRT for Metastatic Non-Small Cell Lung Cancer (NSCLC)

Unknown
NCT05347641Phase 2

Penpulimab Combined With RMA Treatment of Primary Diagnosis of Primary Central Nervous System Lymphoma

Not Yet Recruiting
NCT04970914Phase 2

Anlotinib Plus Penpulimab (AK105) for Chemo-refractory Metastatic Colorectal Cancer:ALTER-C003

Unknown
NCT05244642Phase 3

A Phase III Study to Evaluate the Efficacy and Safety of Penpulimab in the Relapsed and Refractory Classical Hodgkin's Lymphoma

Recruiting
NCT04952493Phase 2

Anlotinib or Penpulimab in Combination With RAI for DTC

Unknown

All 19 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
19