Success Metrics

Clinical Success Rate
76.5%

Based on 52 completed trials

Completion Rate
76%(52/68)
Active Trials
12(14%)
Results Posted
81%(42 trials)
Terminated
16(19%)

Phase Distribution

Ph not_applicable
2
2%
Ph phase_1
23
27%
Ph phase_2
49
58%
Ph phase_3
11
13%

Phase Distribution

23

Early Stage

49

Mid Stage

11

Late Stage

Phase Distribution85 total trials
Phase 1Safety & dosage
23(27.1%)
Phase 2Efficacy & side effects
49(57.6%)
Phase 3Large-scale testing
11(12.9%)
N/ANon-phased studies
2(2.4%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

72.2%

52 of 72 finished

Non-Completion Rate

27.8%

20 ended early

Currently Active

12

trials recruiting

Total Trials

85

all time

Status Distribution
Active(12)
Completed(52)
Terminated(20)
Other(1)

Detailed Status

Completed52
Terminated16
Active, not recruiting9
Withdrawn4
Recruiting3
unknown1

Development Timeline

Analytics

Development Status

Total Trials
85
Active
12
Success Rate
76.5%
Most Advanced
Phase 3

Trials by Phase

Phase 123 (27.1%)
Phase 249 (57.6%)
Phase 311 (12.9%)
N/A2 (2.4%)

Trials by Status

terminated1619%
recruiting34%
withdrawn45%
unknown11%
completed5261%
active_not_recruiting911%

Recent Activity

Clinical Trials (85)

Showing 20 of 85 trialsScroll for more
NCT04267848Phase 3

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

Recruiting
NCT01993810Phase 3

Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer

Active Not Recruiting
NCT03137771Phase 2

Maintenance Chemotherapy With or Without Local Consolidative Therapy in Treating Patients With Stage IV Non-small Cell Lung Cancer

Active Not Recruiting
NCT04895735Phase 2

MC200708 Pemetrexed and Pembrolizumab for the Treatment of Recurrent and/or Metastatic Salivary Gland Cancer

Active Not Recruiting
NCT03228537Phase 1

Atezolizumab, Pemetrexed Disodium, Cisplatin, and Surgery With or Without Radiation Therapy in Treating Patients With Stage I-III Pleural Malignant Mesothelioma

Active Not Recruiting
NCT04092283Phase 3

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Active Not Recruiting
NCT01064648Phase 1

Pemetrexed Disodium and Cisplatin With or Without Cediranib Maleate in Treating Patients With Malignant Pleural Mesothelioma

Active Not Recruiting
NCT02194738Not Applicable

Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

Active Not Recruiting
NCT04158141Phase 3

Testing the Addition of Targeted Radiation Therapy to Surgery and the Usual Chemotherapy Treatment (Pemetrexed and Cisplatin [or Carboplatin]) for Stage I-IIIA Malignant Pleural Mesothelioma

Terminated
NCT06475300Phase 2

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors

Recruiting
NCT02535312Phase 1

Methoxyamine, Cisplatin, and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors or Mesothelioma That Cannot Be Removed by Surgery or Mesothelioma That Is Refractory to Pemetrexed Disodium and Cisplatin or Carboplatin

Active Not Recruiting
NCT04379635Phase 3

Comparing the Efficacy and Safety of a New Additional Treatment With Tislelizumab in Non-Small Cell Lung Cancer (NSCLC)

Active Not Recruiting
NCT03366766Phase 2

Nivolumab Plus Cisplatin/Pemetrexed or Cisplatin/Gemcitabine as Induction in Resectable Non-Small Cell Lung Cancer

Terminated
NCT06659042Phase 2

Perioperative Tislelizumab for Resectable II-IIIB(N2) KRAS-mutated Nonsquamous Non-small Cell Lung Cancer

Recruiting
NCT00324805Phase 3

Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-small Cell Lung Cancer That Was Removed By Surgery

Completed
NCT03971474Phase 2

Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial)

Completed
NCT01001910Phase 2

Pemetrexed and Carboplatin in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Completed
NCT02426658Phase 2

Pemetrexed Disodium in Treating Patients With Stage IV Non-small Cell Lung Cancer and ECOG Performance Status 3

Completed
NCT00101283Phase 2

Pemetrexed Plus Gemcitabine or Carboplatin for Patients With Advanced Malignant Pleural Mesothelioma

Completed
NCT00053209Phase 2

Pemetrexed Disodium and Gemcitabine in Treating Patients With Advanced Cancer of the Urothelium

Completed

Drug Details

Intervention Type
DRUG
Total Trials
85