Success Metrics

Clinical Success Rate
85.7%

Based on 12 completed trials

Completion Rate
86%(12/14)
Active Trials
16(47%)
Results Posted
33%(4 trials)
Terminated
2(6%)

Phase Distribution

Ph phase_1
20
59%
Ph phase_2
12
35%
Ph phase_3
2
6%

Phase Distribution

20

Early Stage

12

Mid Stage

2

Late Stage

Phase Distribution34 total trials
Phase 1Safety & dosage
20(58.8%)
Phase 2Efficacy & side effects
12(35.3%)
Phase 3Large-scale testing
2(5.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

85.7%

12 of 14 finished

Non-Completion Rate

14.3%

2 ended early

Currently Active

16

trials recruiting

Total Trials

34

all time

Status Distribution
Active(20)
Completed(12)
Terminated(2)

Detailed Status

Completed12
Recruiting12
Not yet recruiting4
Active, not recruiting4
Terminated2

Development Timeline

Analytics

Development Status

Total Trials
34
Active
16
Success Rate
85.7%
Most Advanced
Phase 3

Trials by Phase

Phase 120 (58.8%)
Phase 212 (35.3%)
Phase 32 (5.9%)

Trials by Status

completed1235%
not_yet_recruiting412%
recruiting1235%
terminated26%
active_not_recruiting412%

Recent Activity

Clinical Trials (34)

Showing 20 of 34 trialsScroll for more
NCT06697301Phase 2

Safety and Efficacy of EIK1001 in Combo With Pembro Versus Placebo and Pembro as First-Line Therapy in Patients With Advanced Melanoma.

Recruiting
NCT01174121Phase 2

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

Recruiting
NCT03625323Phase 2

Combination Study With Soluble LAG-3 Fusion Protein Eftilagimod Alpha (IMP321) and Pembrolizumab in Patients With Previously Untreated Unresectable or Metastatic NSCLC, or Recurrent PD-X Refractory NSCLC or With Recurrent or Metastatic HNSCC

Completed
NCT05929235Phase 1

A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

Recruiting
NCT05119296Phase 2

Phase II Trial of Pembrolizumab in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer

Active Not Recruiting
NCT03881488Phase 1

Study of CTX-471 as a Monotherapy or in Combination With Pembrolizumab in Patients Post PD-1/PD-L1 Inhibitors in Metastatic or Locally Advanced Malignancies

Completed
NCT07262619Phase 1

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

Recruiting
NCT07264075Phase 3

Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus Pembrolizumab for the Treatment of SCCHN

Not Yet Recruiting
NCT06788990Phase 2

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

Recruiting
NCT06726265Phase 3

Study of Eftilagimod Alfa (Efti) in Combination With Pembrolizumab and Chemotherapy Versus Placebo in Combination With Pembrolizumab and Chemotherapy in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (TACTI-004)

Active Not Recruiting
NCT04977453Phase 1

GI-101/GI-101A as a Single Agent or in Combination With Pembrolizumab or Lenvatinib in Advanced Solid Tumors

Recruiting
NCT04332653Phase 1

NT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid Tumors

Completed
NCT07188246Phase 2

Neoadjuvant, SBRT With Intratumoural Pembrolizumab Followed by Neoadjuvant Chemotherapy in Breast Cancer

Recruiting
NCT07365319Phase 2

A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.

Not Yet Recruiting
NCT06736379Phase 1

Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer

Recruiting
NCT05405595Phase 1

ADG126 in Combination With Pembrolizumab in Patients With Advanced/Metastatic Solid Tumors

Recruiting
NCT04811027Phase 2

Combination Study With Eftilagimod Alpha (a Soluble LAG-3 Fusion Protein) and Pembrolizumab in Patients With Recurrent or Metastatic HNSCC

Completed
NCT04725331Phase 1

A Clinical Trial Assessing BT-001 Alone and in Combination With Pembrolizumab in Metastatic or Advanced Solid Tumors

Terminated
NCT06784648Phase 1

Different Doses of BI-1607 in Combination With Pembrolizumab and Ipilimumab, in Participants With Unresectable or Metastatic Melanoma

Active Not Recruiting
NCT06228326Phase 1

A Study Assessing KB707 for the Treatment of Advanced Solid Tumor Malignancies Affecting the Lungs

Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
34