Success Metrics

Clinical Success Rate
70.6%

Based on 12 completed trials

Completion Rate
71%(12/17)
Active Trials
8(26%)
Results Posted
83%(10 trials)
Terminated
5(16%)

Phase Distribution

Ph phase_1
8
26%
Ph phase_3
13
42%
Ph phase_2
10
32%

Phase Distribution

8

Early Stage

10

Mid Stage

13

Late Stage

Phase Distribution31 total trials
Phase 1Safety & dosage
8(25.8%)
Phase 2Efficacy & side effects
10(32.3%)
Phase 3Large-scale testing
13(41.9%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

70.6%

12 of 17 finished

Non-Completion Rate

29.4%

5 ended early

Currently Active

8

trials recruiting

Total Trials

31

all time

Status Distribution
Active(9)
Completed(12)
Terminated(5)
Other(5)

Detailed Status

Completed12
Recruiting6
unknown5
Terminated5
Active, not recruiting2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
31
Active
8
Success Rate
70.6%
Most Advanced
Phase 3

Trials by Phase

Phase 18 (25.8%)
Phase 210 (32.3%)
Phase 313 (41.9%)

Trials by Status

not_yet_recruiting13%
unknown516%
recruiting619%
completed1239%
active_not_recruiting26%
terminated516%

Recent Activity

Clinical Trials (31)

Showing 20 of 31 trialsScroll for more
NCT07286266Phase 3

A Study to Investigate Mocertatug Rezetecan Compared With Standard of Care in Participants With Platinum-resistant Ovarian Cancer (BEHOLD-Ovarian01)

Recruiting
NCT07743164Phase 3

A Clinical Trial of Raludotatug Deruxtecan (R-DXd) With or Without Bevacizumab in Participants With Ovarian Cancer Who Have Progressed During Treatment With PARP-inhibitors Treatment on First Line Maintenance (MK-5909-008/ENGOT-ov107/GOG-3142 / REJOICE-Ovarian05)

Not Yet Recruiting
NCT07684612Phase 3

A Study to Investigate Mocertatug Rezetecan With Bevacizumab Compared With Platinum Doublet With Bevacizumab in Participants With Platinum-sensitive Ovarian Cancer (BEHOLD-Ovarian02)

Recruiting
NCT06619236Phase 3

Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer

Active Not Recruiting
NCT07213804Phase 3

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

Recruiting
NCT07604766Phase 3

An Extension Study to Assess the Efficacy of Rina-S Compared to Treatment of Investigator's Choice in Participants With Platinum Resistant Ovarian Cancer in China

Recruiting
NCT07218809Phase 3

AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

Recruiting
NCT04729387Phase 3

Alpelisib Plus Olaparib in Platinum-resistant/Refractory, High-grade Serous Ovarian Cancer, With no Germline BRCA Mutation Detected

Terminated
NCT04274426Phase 2

Mirvetuximab Soravtansine (IMGN853), in Folate Receptor Alpha (FRα) High Recurrent Ovarian Cancer

Active Not Recruiting
NCT05613088Phase 2

A Study of MORAb-202 Versus Investigator's Choice Chemotherapy in Female Participants With Platinum-resistant High-grade Serous (HGS) Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Completed
NCT05092360Phase 3

Phase 3 Study of Nemvaleukin Alfa in Combination With Pembrolizumab in Patients With Platinum-Resistant Epithelial Ovarian Cancer (ARTISTRY-7)

Terminated
NCT05261490Phase 1

Study of Maplirpacept (PF-07901801) in Combination With PLD in Patients With Platinum-Resistant Ovarian Cancer

Terminated
NCT03596281Phase 1

Pembrolizumab in Combination with Bevacizumab and Pegylated Liposomal Doxorubicin in Patients with Ovarian Cancer

Completed
NCT03598270Phase 3

Platinum-based Chemotherapy With Atezolizumab and Niraparib in Patients With Recurrent Ovarian Cancer

Completed
NCT03719326Phase 1

A Study to Evaluate Safety/Tolerability of Immunotherapy Combinations in Participants With Triple-Negative Breast Cancer or Gynecologic Malignancies

Completed
NCT05159193Phase 3

Neoadjuvant Treatment Pegylated Liposomal Doxorubicin Plus Cyclophosphamide Sequential Docetaxel Plus Trastuzumab and Pertuzumab Versus Docetaxel Plus Carboplatin Combined With Trastuzumab and Pertuzumab in HER-2 Positive Breast Cancer

Recruiting
NCT04244552Phase 1

A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

Terminated
NCT02584478Phase 3

Phase 1/2a/3 Evaluation of Adding AL3818 to Standard Platinum-Based Chemotherapy in Subjects With Recurrent or Metastatic Endometrial, Ovarian, Fallopian, Primary Peritoneal or Cervical Carcinoma (AL3818-US-002)

Unknown
NCT03639246Phase 1

Efficacy and Safety Study of AVB-S6-500 in Patients With Platinum-Resistant Recurrent Ovarian Cancer

Completed
NCT02865811Phase 2

Pembrolizumab Combined With PLD For Recurrent Platinum Resistant Ovarian, Fallopian Tube Or Peritoneal Cancer

Completed

Drug Details

Intervention Type
DRUG
Total Trials
31