Success Metrics

Clinical Success Rate
90.0%

Based on 18 completed trials

Completion Rate
90%(18/20)
Active Trials
1(4%)
Results Posted
39%(7 trials)
Terminated
2(8%)

Phase Distribution

Ph phase_2
2
8%
Ph phase_3
5
20%
Ph phase_4
8
32%
Ph not_applicable
7
28%
Ph phase_1
2
8%

Phase Distribution

2

Early Stage

2

Mid Stage

13

Late Stage

Phase Distribution24 total trials
Phase 1Safety & dosage
2(8.3%)
Phase 2Efficacy & side effects
2(8.3%)
Phase 3Large-scale testing
5(20.8%)
Phase 4Post-market surveillance
8(33.3%)
N/ANon-phased studies
7(29.2%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

90.0%

18 of 20 finished

Non-Completion Rate

10.0%

2 ended early

Currently Active

1

trials recruiting

Total Trials

25

all time

Status Distribution
Active(1)
Completed(18)
Terminated(2)
Other(4)

Detailed Status

Completed18
unknown4
Terminated2
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
25
Active
1
Success Rate
90.0%
Most Advanced
Phase 4

Trials by Phase

Phase 12 (8.3%)
Phase 22 (8.3%)
Phase 35 (20.8%)
Phase 48 (33.3%)
N/A7 (29.2%)

Trials by Status

completed1872%
terminated28%
unknown416%
recruiting14%

Recent Activity

Clinical Trials (25)

Showing 20 of 25 trialsScroll for more
NCT05470504Phase 2

Study of Growth Hormone Inhibition Using Pegvisomant in Severe Insulin Resistance

Recruiting
NCT03882034Phase 3

Safety and Efficacy of Pegvisomant in Children With Growth Hormone Excess

Completed
NCT01538966Not Applicable

Acromegaly Combination Treatment Study

Terminated
NCT00383708Phase 3

Lanreotide Autogel and Pegvisomant Combination Therapy in Acromegalic Patients

Completed
NCT02952885Phase 3

Strict IGF-1 Control in Acromegaly

Completed
NCT03225040

Bone MicroArchitecture in Acromegaly

Completed
NCT01701973Phase 4

Effect of DPP4 Inhibition on Growth Hormone Secretion

Completed
NCT01261000Not Applicable

Tissue Biomarker for Pegvisomant Action

Completed
NCT02023918Phase 2

Role of Growth Hormone Antagonism in Modulating Insulin Sensitivity in Subjects With Pre-diabetes

Completed
NCT01278342Phase 4

Study to Evaluate the Efficacy and Safety of Sandostatin LAR at High Dose or in Combination Either With GH-receptor Antagonist or Dopamine-agonist in Acromegalic Patients

Completed
NCT02500095Not Applicable

Substrate Metabolism, Growth Hormone Signaling, and Insulin Sensitivity During Fasting

Completed
NCT02668172Phase 4

Pasireotide LAR and Pegvisomant Study in Acromegaly

Unknown
NCT00976508Phase 1

Figitumumab Combined With Pegvisomant For Advanced Solid Tumors

Terminated
NCT01804413Not Applicable

Pegvisomant With Glucagon Test to Assess for Adult Growth Hormone Deficiency

Unknown
NCT00652379Not Applicable

Co-treatment With Pegvisomant and a Somatostatin Analogue (SA) in SA-responsive Acromegalic Patients

Completed
NCT01181973Phase 1

Safety, Tolerability and Relative Bioavailability of Pegvisomant in Healthy Subjects

Completed
NCT00552851Phase 4

Changes of Left Ventricular Mass and Cardiac Function in Patients With Active Acromegaly During Treatment With the Growth Hormone Receptor Antagonist Pegvisomant

Unknown
NCT00969644Not Applicable

The Relationship Between the Growth Hormone (GH)- Insulin Like Growth Factor I (IGF-I) System and the Inflammatory System in Healthy Normal Persons

Unknown
NCT00143416Phase 3

Long Term Study With B2036-PEG

Completed
NCT00068029Phase 4

Pegvisomant And Sandostatin LAR Combination Study

Completed

Drug Details

Intervention Type
DRUG
Total Trials
25