Success Metrics

Clinical Success Rate
72.7%

Based on 8 completed trials

Completion Rate
73%(8/11)
Active Trials
1(8%)
Results Posted
113%(9 trials)
Terminated
3(23%)

Phase Distribution

Ph not_applicable
2
15%
Ph phase_1
7
54%
Ph phase_2
4
31%

Phase Distribution

7

Early Stage

4

Mid Stage

0

Late Stage

Phase Distribution13 total trials
Phase 1Safety & dosage
7(53.8%)
Phase 2Efficacy & side effects
4(30.8%)
N/ANon-phased studies
2(15.4%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

72.7%

8 of 11 finished

Non-Completion Rate

27.3%

3 ended early

Currently Active

1

trials recruiting

Total Trials

13

all time

Status Distribution
Active(1)
Completed(8)
Terminated(3)
Other(1)

Detailed Status

Completed8
Terminated3
unknown1
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
13
Active
1
Success Rate
72.7%
Most Advanced
Phase 2

Trials by Phase

Phase 17 (53.8%)
Phase 24 (30.8%)
N/A2 (15.4%)

Trials by Status

completed862%
unknown18%
terminated323%
active_not_recruiting18%

Recent Activity

Clinical Trials (13)

Showing 13 of 13 trials
NCT02921022Not Applicable

Study Of Gemcitabine, Nab-paclitaxel, PEGPH20 and Rivaroxaban for Advanced Pancreatic Adenocarcinoma

Active Not Recruiting
NCT03193190Phase 1

A Study of Multiple Immunotherapy-Based Treatment Combinations in Participants With Metastatic Pancreatic Ductal Adenocarcinoma (Morpheus-Pancreatic Cancer)

Completed
NCT01959139Phase 1

S1313, PEGPH20 in Treating Patients With Newly Diagnosed Metastatic Pancreatic Cancer

Completed
NCT03979066Phase 2

Study Evaluating NEOadjuvant Immunotherapy in Resectable PANCreatic Ductal Adenocarcinoma

Terminated
NCT01839487Phase 2

PEGPH20 Plus Nab-Paclitaxel Plus Gemcitabine Compared With Nab-Paclitaxel Plus Gemcitabine in Participants With Stage IV Untreated Pancreatic Cancer

Completed
NCT03267940Phase 1

Study of PEGPH20 With Cisplatin (CIS) and Gemcitabine (GEM); PEGPH20 With Atezolizumab (ATEZO), CIS, and GEM; and CIS and GEM Alone in Participants With Previously Untreated, Unresectable, Locally Advanced, or Metastatic Intrahepatic and Extrahepatic Cholangiocarcinoma and Gallbladder Adenocarcinoma

Terminated
NCT02563548Phase 1

A Study of PEGylated Recombinant Human Hyaluronidase (PEGPH20) With Pembrolizumab in Participants With Selected Hyaluronan High Solid Tumors

Completed
NCT02487277Phase 2

PEGPH20, Gemicitabine and Nab-Paclitaxel for Pancreatic Ductal Adenocarcinoma

Terminated
NCT03634332Phase 2

Second-line Study of PEGPH20 and Pembro for HA High Metastatic PDAC

Unknown
NCT01453153Phase 1

Study of Gemcitabine + PEGPH20 vs Gemcitabine Alone in Stage IV Previously Untreated Pancreatic Cancer

Completed
NCT02241187Not Applicable

Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection

Completed
NCT01170897Phase 1

Study of PEGPH20 With Initial Dexamethasone Premedication Given Intravenously to Patients With Advanced Solid Tumors

Completed
NCT00834704Phase 1

Safety Study of PEGPH20 Given to Patients With Advanced Solid Tumors

Completed

All 13 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
13