Success Metrics

Clinical Success Rate
100.0%

Based on 13 completed trials

Completion Rate
100%(13/13)
Active Trials
1(7%)
Results Posted
62%(8 trials)

Phase Distribution

Ph phase_1
1
7%
Ph phase_2
2
14%
Ph phase_3
3
21%
Ph phase_4
7
50%

Phase Distribution

1

Early Stage

2

Mid Stage

10

Late Stage

Phase Distribution13 total trials
Phase 1Safety & dosage
1(7.7%)
Phase 2Efficacy & side effects
2(15.4%)
Phase 3Large-scale testing
3(23.1%)
Phase 4Post-market surveillance
7(53.8%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

100.0%

13 of 13 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

1

trials recruiting

Total Trials

14

all time

Status Distribution
Active(1)
Completed(13)

Detailed Status

Completed13
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
14
Active
1
Success Rate
100.0%
Most Advanced
Phase 4

Trials by Phase

Phase 11 (7.7%)
Phase 22 (15.4%)
Phase 33 (23.1%)
Phase 47 (53.8%)

Trials by Status

completed1393%
recruiting17%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT04745910Phase 4

Pegloticase for the Reduction of Uric Acid in Patients With Tumor Lysis Syndrome

Completed
NCT07388498Phase 3

A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

Recruiting
NCT06229145Phase 4

A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout

Completed
NCT04762498Phase 4

A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL)

Completed
NCT04772313Phase 4

Pegloticase and Methotrexate Co-administered in Participants With Uncontrolled Gout Who Previously Failed Pegloticase Monotherapy

Completed
NCT03994731Phase 4

Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gout

Completed
NCT04087720Phase 4

Study of Pegloticase in Participants With Uncontrolled Gout Who Have Had a Kidney Transplant

Completed
NCT03635957Phase 4

Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout

Completed
NCT02598596Phase 2

Tolerization Reduces Intolerance to Pegloticase and Prolongs the Urate Lowering Effect

Completed
NCT01466166

Observational Study of the Use of Pegloticase (KRYSTEXXA®) in Refractory Chronic Gout

Completed
NCT00111657Phase 2

Pegylated Recombinant Mammalian Uricase (PEG-uricase) as Treatment for Refractory Gout

Completed
NCT01739660Phase 1

Study to Assess Pegloticase (KRYSTEXXA®) in Patients on Hemodialysis

Completed
NCT01356498Phase 3

Open-Label Extension Study for Patients Who Completed a Phase 3 Double-blind Study of PEG-uricase for Symptomatic Gout

Completed
NCT00325195Phase 3

Safety and Efficacy Study of PEG-uricase in the Treatment of Hyperuricemic Patients With Symptomatic Gout

Completed

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14