Success Metrics

Clinical Success Rate
54.8%

Based on 17 completed trials

Completion Rate
55%(17/31)
Active Trials
4(10%)
Results Posted
65%(11 trials)
Terminated
14(36%)

Phase Distribution

Ph phase_1
29
74%
Ph phase_2
9
23%
Ph early_phase_1
1
3%

Phase Distribution

30

Early Stage

9

Mid Stage

0

Late Stage

Phase Distribution39 total trials
Early Phase 1First-in-human
1(2.6%)
Phase 1Safety & dosage
29(74.4%)
Phase 2Efficacy & side effects
9(23.1%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

53.1%

17 of 32 finished

Non-Completion Rate

46.9%

15 ended early

Currently Active

4

trials recruiting

Total Trials

39

all time

Status Distribution
Active(4)
Completed(17)
Terminated(15)
Other(3)

Detailed Status

Completed17
Terminated14
Active, not recruiting3
unknown3
Recruiting1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
39
Active
4
Success Rate
54.8%
Most Advanced
Phase 2

Trials by Phase

Early Phase 11 (2.6%)
Phase 129 (74.4%)
Phase 29 (23.1%)

Trials by Status

recruiting13%
withdrawn13%
active_not_recruiting38%
terminated1436%
unknown38%
completed1744%

Recent Activity

Clinical Trials (39)

Showing 20 of 39 trialsScroll for more
NCT04895748Phase 1

DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

Terminated
NCT03891953Phase 1

Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

Active Not Recruiting
NCT02936102Phase 1

A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

Terminated
NCT04544111Phase 2

PDR001 Combination Therapy for Radioiodine-Refractory Thyroid Cancer

Active Not Recruiting
NCT04058756Phase 1

Rollover Study for Continued Safety and Tolerability in Subjects Treated With Spartalizumab Alone or in Combination With Other Study Treatments

Active Not Recruiting
NCT07157345Phase 1

Testing if PDR-001 Can Safely and Effectively Remove Harmful Brain Protein in Parkinson's Disease

Recruiting
NCT01351103Phase 1

A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands

Completed
NCT03294694Phase 1

Ribociclib + PDR001 in Breast Cancer and Ovarian Cancer

Terminated
NCT04237649Early Phase 1

KAZ954 Alone and With PDR001, NZV930 and NIR178 in Advanced Solid Tumors

Terminated
NCT03066648Phase 1

Study of PDR001 and/or MBG453 in Combination With Decitabine in Patients With AML or High Risk MDS

Completed
NCT03549000Phase 1

A Phase I/Ib Study of NZV930 Alone and in Combination With PDR001 and /or NIR178 in Patients With Advanced Malignancies.

Terminated
NCT02325739Phase 1

FGF401 in HCC and Solid Tumors Characterized by Positive FGFR4 and KLB Expression

Completed
NCT03207867Phase 2

A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

Terminated
NCT03301896Phase 1

Study of the Safety and Efficacy of LHC165 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies

Terminated
NCT03484923Phase 2

Study of Efficacy and Safety of Novel Spartalizumab Combinations in Patients With Previously Treated Unresectable or Metastatic Melanoma

Completed
NCT02829723Phase 1

A Study of BLZ945 Single Agent or BLZ945 in Combination With PDR001 in Advanced Solid Tumors

Terminated
NCT02608268Phase 1

Phase I-Ib/II Study of MBG453 as Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies

Terminated
NCT02452268Phase 1

A Phase I/Ib Study of NIZ985 in Combination With PDR001 in Adults With Metastatic Cancers

Terminated
NCT03499899Phase 2

A Study of Efficacy and Safety of LAG525 in Combination With Spartalizumab, or With Spartalizumab and Carboplatin, or With Carboplatin, in Patients With Advanced Triple-negative Breast Cancer

Completed
NCT02890069Phase 1

A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat

Completed

Drug Details

Intervention Type
DRUG
Total Trials
39