Biological
PD-1 Knockout T Cells
PD-1 Knockout T Cells is a biological therapy with 6 clinical trials. Historical success rate of 100.0%.
Total Trials
6
Max Phase
—
Type
BIOLOGICAL
Molecule
—
Success Metrics
Clinical Success Rate
100.0%
Based on 2 completed trials
Completion Rate
100%(2/2)
Active Trials
0(0%)
Results Posted
50%(1 trials)
Phase Distribution
Ph not_applicable
1
17%
Ph phase_1
4
67%
Phase Distribution
4
Early Stage
0
Mid Stage
0
Late Stage
Phase Distribution5 total trials
Phase 1Safety & dosage
4(80.0%)
N/ANon-phased studies
1(20.0%)
Highest Phase Reached
Phase 1Trial Status & Enrollment
Completion Rate
40.0%
2 of 5 finished
Non-Completion Rate
60.0%
3 ended early
Currently Active
0
trials recruiting
Total Trials
6
all time
Status Distribution
Completed(2)
Terminated(3)
Other(1)
Detailed Status
Withdrawn3
Completed2
unknown1
Development Timeline
Analytics
Development Status
Total Trials
6
Active
0
Success Rate
100.0%
Most Advanced
Phase 1
Trials by Phase
Phase 14 (80.0%)
N/A1 (20.0%)
Trials by Status
unknown117%
completed233%
withdrawn350%
Recent Activity
0 active trials
Showing 5 of 6
completedphase_1
PD-1 Knockout Engineered T Cells for Metastatic Non-small Cell Lung Cancer
NCT02793856
completednot_applicable
PD-1 Knockout Engineered T Cells for Advanced Esophageal Cancer
NCT03081715
withdrawn
PD-1 Knockout Engineered T Cells for Castration Resistant Prostate Cancer
NCT02867345
withdrawnphase_1
PD-1 Knockout Engineered T Cells for Muscle-invasive Bladder Cancer
NCT02863913
withdrawnphase_1
PD-1 Knockout Engineered T Cells for Metastatic Renal Cell Carcinoma.
NCT02867332
Clinical Trials (6)
Showing 6 of 6 trials
NCT02793856Phase 1
PD-1 Knockout Engineered T Cells for Metastatic Non-small Cell Lung Cancer
NCT03081715Not Applicable
PD-1 Knockout Engineered T Cells for Advanced Esophageal Cancer
NCT02867345
PD-1 Knockout Engineered T Cells for Castration Resistant Prostate Cancer
NCT02863913Phase 1
PD-1 Knockout Engineered T Cells for Muscle-invasive Bladder Cancer
NCT02867332Phase 1
PD-1 Knockout Engineered T Cells for Metastatic Renal Cell Carcinoma.
NCT03525652Phase 1
Therapeutic Vaccine Plus PD-1 Knockout in Prostate Cancer Treatment
All 6 trials loaded
Drug Details
- Intervention Type
- BIOLOGICAL
- Total Trials
- 6