Success Metrics

Clinical Success Rate
100.0%

Based on 12 completed trials

Completion Rate
100%(12/12)
Active Trials
1(7%)
Results Posted
67%(8 trials)

Phase Distribution

Ph phase_2
7
50%
Ph phase_1
6
43%
Ph phase_3
1
7%

Phase Distribution

6

Early Stage

7

Mid Stage

1

Late Stage

Phase Distribution14 total trials
Phase 1Safety & dosage
6(42.9%)
Phase 2Efficacy & side effects
7(50.0%)
Phase 3Large-scale testing
1(7.1%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

100.0%

12 of 12 finished

Non-Completion Rate

0.0%

0 ended early

Currently Active

1

trials recruiting

Total Trials

14

all time

Status Distribution
Active(1)
Completed(12)
Other(1)

Detailed Status

Completed12
Active, not recruiting1
unknown1

Development Timeline

Analytics

Development Status

Total Trials
14
Active
1
Success Rate
100.0%
Most Advanced
Phase 3

Trials by Phase

Phase 16 (42.9%)
Phase 27 (50.0%)
Phase 31 (7.1%)

Trials by Status

completed1286%
active_not_recruiting17%
unknown17%

Recent Activity

Clinical Trials (14)

Showing 14 of 14 trials
NCT01723774Phase 2

PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer

Active Not Recruiting
NCT01356628Phase 2

A Clinical Research Study to Determine Whether PD 0332991 May Be Effective in Treating Patients With Liver Cancer

Completed
NCT01740427Phase 3

A Study of Palbociclib (PD-0332991) + Letrozole vs. Letrozole For 1st Line Treatment Of Postmenopausal Women With ER+/HER2- Advanced Breast Cancer (PALOMA-2)

Completed
NCT01037790Phase 2

Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer

Completed
NCT01684215Phase 2

A Study Of Oral Palbociclib (PD-0332991), A CDK4/6 Inhibitor, As Single Agent In Japanese Patients With Advanced Solid Tumors Or In Combination With Letrozole For The First-Line Treatment Of Postmenopausal Japanese Patients With ER (+) HER2 (-) Advanced Breast Cancer

Completed
NCT01536743Phase 2

A Open Label Study of the Efficacy and Safety of PD0332991 a Selective Inhibitor of the Cyclin Dependent Kinases 4 and 6 in Patients With Recurrent Ovarian Cancer Demonstrating Rb-proficiency and Low p16 Expression

Completed
NCT01320592Phase 1

PD0332991/Paclitaxel in Advanced Breast Cancer

Completed
NCT01522989Phase 1

PD-0332991, 5-FU, and Oxaliplatin for Advanced Solid Tumor Malignancies

Unknown
NCT02008734Phase 2

Randomized Phase II Study to Assess PD 0332991 in Breast Cancer

Completed
NCT01291017Phase 2

Cyclin Dependent Kinase (CDK)4/6 Inhibitor, PD0332991 in Advanced Non-small Cell Lung Cancer NSCLC.

Completed
NCT00141297Phase 1

A Study Of Oral Palbociclib (PD-0332991), A Cyclin-Dependent Kinase Inhibitor, In Patients With Advanced Cancer

Completed
NCT00420056Phase 1

An Investigational Study Drug, Palbociclib (PD-0332991), Is Being Studied In Patients With Mantle Cell Lymphoma. Patients Must Have Received Prior Treatment(s) For Mantle Cell Lymphoma.

Completed
NCT01756781Phase 1

A Drug-Drug Interaction Study To Investigate The Potential For Multiple Doses Of Palbociclib (PD-0332991) To Alter The Pharmacokinetics Of Oral Midazolam In Adult Healthy Women of Non-Childbearing Potential.

Completed
NCT01602887Phase 1

Relative Bioavailability Study

Completed

All 14 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
14