Success Metrics

Clinical Success Rate
78.3%

Based on 101 completed trials

Completion Rate
78%(101/129)
Active Trials
12(8%)
Results Posted
54%(55 trials)
Terminated
28(18%)

Phase Distribution

Ph not_applicable
5
3%
Ph phase_1
51
33%
Ph phase_2
79
51%
Ph phase_4
4
3%
Ph early_phase_1
2
1%
Ph phase_3
10
6%

Phase Distribution

53

Early Stage

79

Mid Stage

14

Late Stage

Phase Distribution151 total trials
Early Phase 1First-in-human
2(1.3%)
Phase 1Safety & dosage
51(33.8%)
Phase 2Efficacy & side effects
79(52.3%)
Phase 3Large-scale testing
10(6.6%)
Phase 4Post-market surveillance
4(2.6%)
N/ANon-phased studies
5(3.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

75.9%

101 of 133 finished

Non-Completion Rate

24.1%

32 ended early

Currently Active

12

trials recruiting

Total Trials

156

all time

Status Distribution
Active(14)
Completed(101)
Terminated(32)
Other(9)

Detailed Status

Completed101
Terminated28
unknown9
Active, not recruiting8
Recruiting4
Withdrawn4

Development Timeline

Analytics

Development Status

Total Trials
156
Active
12
Success Rate
78.3%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (1.3%)
Phase 151 (33.8%)
Phase 279 (52.3%)
Phase 310 (6.6%)
Phase 44 (2.6%)
N/A5 (3.3%)

Trials by Status

recruiting43%
not_yet_recruiting21%
unknown96%
withdrawn43%
completed10165%
active_not_recruiting85%
terminated2818%

Recent Activity

Clinical Trials (156)

Showing 20 of 156 trialsScroll for more
NCT02331498Phase 1

Phase I/II Study of Pazopanib+ Temozolomide in Patients With Newly Diagnosed Glioblastoma Multiforme

Active Not Recruiting
NCT02180867Phase 2

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Active Not Recruiting
NCT06239272Phase 1

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Recruiting
NCT01642017Phase 1

Phase I Clinical and Pharmacokinetic Study of Pazopanib in a Population of Frail Elderly Patients According SIOG Criteria

Terminated
NCT05432791Phase 2

Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Active Not Recruiting
NCT02555748Phase 4

Therapeutic Drug Monitoring of Sunitinib and Pazopanib in Advanced or Metastatic Renal Cell Carcinoma

Completed
NCT03850964Phase 2

Effects of Pazopanib on Hereditary Hemorrhagic Telangiectasia Related Epistaxis and Anemia (Paz)

Active Not Recruiting
NCT07444619Phase 1

A Phase I Study of Pazopanib in Combination With Trabectedin, Ipilimumab and Nivolumab (TraPIN) in Pediatric and Young Adult Patients With Recurrent Soft Tissue Sarcomas

Not Yet Recruiting
NCT04199026Not Applicable

Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent Sarcoma

Recruiting
NCT05180695Phase 1

HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas

Active Not Recruiting
NCT01217931Phase 2

Sequential Two-agent Assessment in Renal Cell Carcinoma Therapy: The START Trial

Active Not Recruiting
NCT01931098Phase 2

Oral Pazopanib Plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) Without Prior Bevacizumab Exposure and (B) After Failing Prior Bevacizumab

Completed
NCT06263231Phase 3

A Study to Investigate Efficacy & Safety of Intratumoral INT230-6 Compared to US Standard of Care in Adults With Soft Tissue Sarcomas (INVINCIBLE-3)

Active Not Recruiting
NCT03260894Phase 3

Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care in mRCC (KEYNOTE-679/ECHO-302)

Completed
NCT07087158Phase 2

A Study of IBR854 Combined With Pazopanib Versus Pazopanib in Advanced Renal Cell Carcinoma

Not Yet Recruiting
NCT03592472Phase 3

A Study of Pazopanib With or Without Abexinostat in Patients With Locally Advanced or Metastatic Renal Cell Carcinoma (RENAVIV)

Recruiting
NCT00720941Phase 3

Pazopanib Versus Sunitinib in the Treatment of Locally Advanced and/or Metastatic Renal Cell Carcinoma

Completed
NCT01147822Phase 2

Pazopanib Versus Sunitinib in the Treatment of Asian Subjects With Locally Advanced and/or Metastatic Renal Cell Carcinoma

Completed
NCT06816771Phase 2

Evaluation of the Efficacy and Safety of Pazopanib in Combination with TGI/CIV for Recurrent or Refractory Rhabdomyosarcoma in Children or Adolescents

Recruiting
NCT02203760Phase 2

Pazopanib Vs. Pazopanib Plus Gemcitabine

Active Not Recruiting

Drug Details

Intervention Type
DRUG
Total Trials
156