Success Metrics

Clinical Success Rate
91.7%

Based on 11 completed trials

Completion Rate
92%(11/12)
Active Trials
0(0%)
Results Posted
9%(1 trials)
Terminated
1(8%)

Phase Distribution

Ph phase_2
4
31%
Ph phase_1
9
69%

Phase Distribution

9

Early Stage

4

Mid Stage

0

Late Stage

Phase Distribution13 total trials
Phase 1Safety & dosage
9(69.2%)
Phase 2Efficacy & side effects
4(30.8%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

84.6%

11 of 13 finished

Non-Completion Rate

15.4%

2 ended early

Currently Active

0

trials recruiting

Total Trials

13

all time

Status Distribution
Completed(11)
Terminated(2)

Detailed Status

Completed11
Terminated1
Withdrawn1

Development Timeline

Analytics

Development Status

Total Trials
13
Active
0
Success Rate
91.7%
Most Advanced
Phase 2

Trials by Phase

Phase 19 (69.2%)
Phase 24 (30.8%)

Trials by Status

completed1185%
terminated18%
withdrawn18%

Recent Activity

Clinical Trials (13)

Showing 13 of 13 trials
NCT00219297Phase 2

Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer

Completed
NCT00411528Phase 2

Efficacy and Safety of Patupilone in Men (≥18 Years) With Metastatic Hormone Refractory Prostate Cancer

Completed
NCT00426582Phase 1

Combination Trial of Patupilone and Carboplatin in Adult Patients With Advanced Solid Tumors

Completed
NCT00426140Phase 1

Pharmacokinetics of Patupilone After a Single Intravenous Administration in Patients With Advance Solid Tumor Malignancies.

Completed
NCT00273312Phase 2

Patupilone Activity in Advanced/Metastatic Hepatocellular Carcinoma

Completed
NCT00171834Phase 1

Dose Escalating Study of the Safety and Efficacy of Patupilone, q3w, in Patients With Non-small Cell Lung Cancer

Completed
NCT00496600Phase 1

Phase I Study of Patupilone and RAD001

Completed
NCT00442741Phase 1

Evaluate the Effects of Patupilone on the Pharmacokinetics of Midazolam and Omeprazole in Patients With Advanced Malignancies (Extension)

Withdrawn
NCT00715013Phase 1

Patupilone (EPO 906) in Patients With Recurrent or Progressive Glioblastoma

Completed
NCT00407251Phase 2

Study of Patupilone in Prostate Cancer Patients Who Progress After Hormone Therapy and Docetaxel Chemotherapy

Completed
NCT00412789Phase 1

Efficacy and Safety of Patupilone in Patients With Advanced Solid Tumors in Japan

Completed
NCT00448396Phase 1

Evaluate the Effects of Patupilone on the Pharmacokinetics and Pharmacodynamics of Warfarin in Patients With Advanced Malignancies

Completed
NCT00468260Phase 1

The Effects of Patupilone on the Pharmacokinetics and Pharmacodynamics of Warfarin in Patients With Advanced Malignancies

Terminated

All 13 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
13