Success Metrics

Clinical Success Rate
78.5%

Based on 51 completed trials

Completion Rate
78%(51/65)
Active Trials
2(3%)
Results Posted
63%(32 trials)
Terminated
14(20%)

Phase Distribution

Ph not_applicable
7
10%
Ph phase_4
16
23%
Ph phase_2
17
24%
Ph phase_3
17
24%
Ph early_phase_1
2
3%
Ph phase_1
9
13%

Phase Distribution

11

Early Stage

17

Mid Stage

33

Late Stage

Phase Distribution68 total trials
Early Phase 1First-in-human
2(2.9%)
Phase 1Safety & dosage
9(13.2%)
Phase 2Efficacy & side effects
17(25.0%)
Phase 3Large-scale testing
17(25.0%)
Phase 4Post-market surveillance
16(23.5%)
N/ANon-phased studies
7(10.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

76.1%

51 of 67 finished

Non-Completion Rate

23.9%

16 ended early

Currently Active

2

trials recruiting

Total Trials

70

all time

Status Distribution
Active(2)
Completed(51)
Terminated(16)
Other(1)

Detailed Status

Completed51
Terminated14
Withdrawn2
unknown1
Active, not recruiting1
Recruiting1

Development Timeline

Analytics

Development Status

Total Trials
70
Active
2
Success Rate
78.5%
Most Advanced
Phase 4

Trials by Phase

Early Phase 12 (2.9%)
Phase 19 (13.2%)
Phase 217 (25.0%)
Phase 317 (25.0%)
Phase 416 (23.5%)
N/A7 (10.3%)

Trials by Status

unknown11%
terminated1420%
active_not_recruiting11%
recruiting11%
withdrawn23%
completed5173%

Recent Activity

Clinical Trials (70)

Showing 20 of 70 trialsScroll for more
NCT05664880Early Phase 1

A PiLot ClinicaL TrIal of ParicAlcitol for ChroNiC PancrEatitis

Active Not Recruiting
NCT04064827Phase 3

A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)

Terminated
NCT04524702Phase 2

Paricalcitol and Hydroxychloroquine in Combination With Gemcitabine and Nab-Paclitaxel for Advanced Pancreatic Cancer

Completed
NCT04054362Phase 2

Paricalcitol Addition to Chemotherapy in Patients With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Completed
NCT02754726Phase 2

Combination Therapy for Patients With Untreated Metastatic Pancreatic Ductal Adenocarcinoma

Completed
NCT02030860Phase 1

A Study of Neoadjuvant Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer

Completed
NCT03520790Phase 1

Paricalcitol Plus Gemcitabine and Nab-paclitaxel in Metastatic Pancreatic Cancer

Terminated
NCT02378805

Alport Therapy Registry - European Initiative Towards Delaying Renal Failure in Alport Syndrome

Recruiting
NCT02876211Phase 4

Paricalcitol Improves Anemia of Inflammation

Terminated
NCT03519308Early Phase 1

A Pilot Study of Perioperative Nivolumab and Paricalcitol to Target the Microenvironment in Resectable Pancreatic Cancer

Terminated
NCT04617067Phase 2

Paricalcitol Trial: Phase II, Open Label Clinical Trial of Paricalcitol in Combination With Gemcitabine/ Nab-Paclitaxel Therapy in Advanced Pancreatic Cancer

Completed
NCT01725113Phase 4

Management of Mineral and Bone Disease in Hemodialysis-Calcitriol vs. Paricalcitol

Terminated
NCT02930902Phase 1

Pembrolizumab and Paricalcitol With or Without Chemotherapy in Patients With Pancreatic Cancer That Can Be Removed by Surgery

Completed
NCT03331562Phase 2

A SU2C Catalyst® Trial of a PD1 Inhibitor With or Without a Vitamin D Analog for the Maintenance of Pancreatic Cancer

Completed
NCT03883919Phase 1

Liposomal Irinotecan Plus 5-FU / LV Combined With Paricalcitol in Patients With Advanced Pancreatic Cancer Progressed on Gemcitabine-based Therapy

Completed
NCT03300921Phase 1

A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer A Phase Ib Pharmacodynamic Study of Neoadjuvant Paricalcitol in Resectable Pancreatic Cancer

Terminated
NCT04994080Phase 3

A Study to Assess the Efficacy and Safety of Paricalcitol in the Treatment of Chronic Kidney Disease With Secondary Hyperparathyroidism

Unknown
NCT01506947Phase 4

A Pilot Clinical Study Evaluating the Effect of Parathyroid Hormone (PTH) Lowering On Erythropoietin Consumption in Calcitriol-Resistant Patients

Completed
NCT00417612Phase 3

Effectiveness of Paricalcitol in Reducing Parathyroid Hormone (PTH) Levels in X-linked Hypophosphatemic Rickets

Completed
NCT01939977Phase 4

Efficacy and Safety of Paricalcitol in the Reduction of Secondary Hyperparathyroidism After Kidney Transplantation.

Completed

Drug Details

Intervention Type
DRUG
Total Trials
70