Success Metrics

Clinical Success Rate
69.8%

Based on 44 completed trials

Completion Rate
70%(44/63)
Active Trials
3(4%)
Results Posted
80%(35 trials)
Terminated
19(25%)

Phase Distribution

Ph phase_4
1
1%
Ph phase_3
3
4%
Ph phase_2
27
35%
Ph phase_1
44
57%

Phase Distribution

44

Early Stage

27

Mid Stage

4

Late Stage

Phase Distribution75 total trials
Phase 1Safety & dosage
44(58.7%)
Phase 2Efficacy & side effects
27(36.0%)
Phase 3Large-scale testing
3(4.0%)
Phase 4Post-market surveillance
1(1.3%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

63.8%

44 of 69 finished

Non-Completion Rate

36.2%

25 ended early

Currently Active

3

trials recruiting

Total Trials

77

all time

Status Distribution
Active(3)
Completed(44)
Terminated(25)
Other(5)

Detailed Status

Completed44
Terminated19
Withdrawn6
unknown5
Recruiting2
Active, not recruiting1

Development Timeline

Analytics

Development Status

Total Trials
77
Active
3
Success Rate
69.8%
Most Advanced
Phase 4

Trials by Phase

Phase 144 (58.7%)
Phase 227 (36.0%)
Phase 33 (4.0%)
Phase 41 (1.3%)

Trials by Status

unknown56%
completed4457%
withdrawn68%
recruiting23%
terminated1925%
active_not_recruiting11%

Recent Activity

Clinical Trials (77)

Showing 20 of 77 trialsScroll for more
NCT02386800Phase 4

CINC424A2X01B Rollover Protocol

Active Not Recruiting
NCT01245179Phase 1

Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease

Recruiting
NCT01324635Phase 1

Panobinostat and Stereotactic Radiation Therapy in Treating Patients With Brain Tumors

Terminated
NCT02506959Phase 2

Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple Myeloma

Completed
NCT04897880Phase 2

A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT

Terminated
NCT03878524Phase 1

Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial

Terminated
NCT02471430Phase 1

Reducing the Residual Reservoir of HIV-1 Infected Cells in Patients Receiving Antiretroviral Therapy

Completed
NCT04341311Phase 1

Phase I Study of Marizomib + Panobinostat for Children With DIPG

Terminated
NCT01693601Phase 1

Panobinostat and Ruxolitinib In MyElofibrosis (PRIME Trial)

Completed
NCT01301807Phase 1

Panobinostat and Carfilzomib in Treating Participants With Relapsed or Refractory Multiple Myeloma

Completed
NCT05725200Phase 2

Study to Investigate Outcome of Individualized Treatment in Patients With Metastatic Colorectal Cancer

Recruiting
NCT04326764Phase 3

Panobinostat Maintenance After HSCT fo High-risk AML and MDS

Terminated
NCT02032810Phase 1

Phase I of Histone Deacetylase (HDAC) Inhibitor Panobinostat With Ipilimumab With Unresectable III/IV Melanoma

Completed
NCT02890069Phase 1

A Study of PDR001 in Combination With LCL161, Everolimus or Panobinostat

Completed
NCT02722941Phase 2

Panobinostat (LBH589): Multiple Myeloma - Autologous Hematopoietic Cell Transplantation (HCT)

Completed
NCT01582009Phase 1

Panobinostat and Everolimus in Treating Patients With Metastatic or Unresectable Renal Cell Cancer That Does Not Respond to Treatment With Sunitinib Malate or Sorafenib Tosylate

Terminated
NCT01261247Phase 2

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Completed
NCT03256045Phase 2

Panobinostat, Carfilzomib, and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma

Terminated
NCT01658241Phase 2

Panobinostat Biological Correlates Study

Completed
NCT01496118Phase 1

Study of the Combination of Panobinostat and Carfilzomib in Patients With Relapsed/Refractory Multiple Myeloma

Completed

Drug Details

Intervention Type
DRUG
Total Trials
77