Success Metrics

Clinical Success Rate
88.9%

Based on 8 completed trials

Completion Rate
89%(8/9)
Active Trials
6(25%)
Results Posted
88%(7 trials)
Terminated
1(4%)

Phase Distribution

Ph phase_1
8
33%
Ph phase_2
14
58%
Ph phase_3
1
4%
Ph early_phase_1
1
4%

Phase Distribution

9

Early Stage

14

Mid Stage

1

Late Stage

Phase Distribution24 total trials
Early Phase 1First-in-human
1(4.2%)
Phase 1Safety & dosage
8(33.3%)
Phase 2Efficacy & side effects
14(58.3%)
Phase 3Large-scale testing
1(4.2%)

Highest Phase Reached

Phase 3

Trial Status & Enrollment

Completion Rate

66.7%

8 of 12 finished

Non-Completion Rate

33.3%

4 ended early

Currently Active

6

trials recruiting

Total Trials

24

all time

Status Distribution
Active(7)
Completed(8)
Terminated(4)
Other(5)

Detailed Status

Completed8
unknown5
Active, not recruiting4
Withdrawn3
Recruiting2
Not yet recruiting1

Development Timeline

Analytics

Development Status

Total Trials
24
Active
6
Success Rate
88.9%
Most Advanced
Phase 3

Trials by Phase

Early Phase 11 (4.2%)
Phase 18 (33.3%)
Phase 214 (58.3%)
Phase 31 (4.2%)

Trials by Status

withdrawn313%
unknown521%
active_not_recruiting417%
not_yet_recruiting14%
recruiting28%
completed833%
terminated14%

Recent Activity

Clinical Trials (24)

Showing 20 of 24 trialsScroll for more
NCT04164199Phase 3

Study of Tislelizumab, Pamiparib, and Other Investigational Agents in Participants With Advanced Malignancies

Active Not Recruiting
NCT05494580Phase 1

Pamiparib Plus Surufatinib in Patients With Platinum-resistant Ovarian Cancer

Completed
NCT05526924Phase 1

Dosing Study of Radiation Combined With Tislelizumab and Pamiparib in Patients With Previously Treated Head and Neck Cancer

Recruiting
NCT05038839Phase 1

Cabozantinib and Pamiparib for the Treatment of Advanced of Refractory Solid Tumors

Active Not Recruiting
NCT05044871Phase 2

Biomarker-driven Targeted Therapy in Patients With Recurrent Platinum-resistant Epithelial Ovarian Cancer

Completed
NCT04614909Early Phase 1

Study of Pamiparib in Newly Diagnosed and rGBM

Active Not Recruiting
NCT03150862Phase 1

A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma

Completed
NCT03333915Phase 1

Study of the Efficacy, Safety and Pharmacokinetics of Pamiparib (BGB-290) in Participants With Advanced Solid Tumors

Completed
NCT03150810Phase 1

Study to Assess Safety, Tolerability and Clinical Activity of BGB-290 in Combination With Temozolomide (TMZ) in Participants With Locally Advanced or Metastatic Solid Tumors

Completed
NCT05652283Phase 2

Pamiparib Combined With Surufatinib for the Neoadjuvant Treatment of Unresectable Ovarian Cancer

Active Not Recruiting
NCT06692491Phase 2

Study of Precision Treatment for Rare Tumours in China Guided by PDO and NGS

Not Yet Recruiting
NCT03994211Phase 1

Study to Investigate the Effect of Rifampin and Itraconazole on the Action of Pamiparib in Participants With Cancer

Completed
NCT03427814Phase 2

Study of BGB-290 or Placebo in Participants With Advanced or Inoperable Gastric Cancer

Completed
NCT06387056Phase 2

Genomic Biomarker-guided Neoadjuvant Therapy for Prostate Cancer (SEGNO)

Recruiting
NCT05489926Phase 2

A Study to Explore Pamiparib Treatment in Epithelial Ovarian Cancer After Prior PARP Inhibitor Exposure

Unknown
NCT04603365Phase 2

Pamiparib and Temozolomide for the Treatment of Hereditary Leiomyomatosis and Renal Cell Cancer

Withdrawn
NCT04985721Phase 2

A Trial of Pamiparib With Tislelizumab in Patients With Advanced Tumours With Homologous Recombination Repair Defects

Unknown
NCT05376722Phase 2

A Study of Pamiparib Combined With Abiraterone Acetate in Neoadjuvant Treatment of Prostate Cancer

Unknown
NCT05483543Phase 2

Pamiparib for Consolidation Treatment of Unprogressed LS-SCLC After Concurrent Chemoradiotherapy

Unknown
NCT04796454Phase 2

Pamiparib and Low Dose Temozolomide In Patients With Platinum Sensitive Biliary Tract Cancer

Withdrawn

Drug Details

Intervention Type
DRUG
Total Trials
24