Success Metrics

Clinical Success Rate
88.9%

Based on 8 completed trials

Completion Rate
89%(8/9)
Active Trials
8(42%)
Results Posted
25%(2 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_2
8
42%
Ph phase_4
1
5%
Ph phase_1
5
26%
Ph phase_3
4
21%

Phase Distribution

5

Early Stage

8

Mid Stage

5

Late Stage

Phase Distribution18 total trials
Phase 1Safety & dosage
5(27.8%)
Phase 2Efficacy & side effects
8(44.4%)
Phase 3Large-scale testing
4(22.2%)
Phase 4Post-market surveillance
1(5.6%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

72.7%

8 of 11 finished

Non-Completion Rate

27.3%

3 ended early

Currently Active

8

trials recruiting

Total Trials

19

all time

Status Distribution
Active(8)
Completed(8)
Terminated(3)

Detailed Status

Completed8
Recruiting6
Withdrawn2
Active, not recruiting2
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
19
Active
8
Success Rate
88.9%
Most Advanced
Phase 4

Trials by Phase

Phase 15 (27.8%)
Phase 28 (44.4%)
Phase 34 (22.2%)
Phase 41 (5.6%)

Trials by Status

withdrawn211%
recruiting632%
terminated15%
completed842%
active_not_recruiting211%

Recent Activity

Clinical Trials (19)

Showing 19 of 19 trials
NCT02630693Phase 2

Two Different Schedules of Palbociclib + Second Line Endocrine Therapy in Estrogen Receptor Positive, HER2 Neg Advanced/Metastatic Breast Cancer

Completed
NCT03820830Phase 3

Palbociclib for HR Positive / HER2-negative Isolated Locoregional Recurrence of Breast Cancer

Active Not Recruiting
NCT06377852Phase 3

The CDK4/6 Inhibitor Dosing Knowledge (CDK) Study

Recruiting
NCT07002177Phase 1

A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC

Recruiting
NCT05069038Phase 2

Clinical Trial Assessing the Safety of Neoadjuvant Palbociclib in Combination With Endocrine Therapy

Active Not Recruiting
NCT04563507Phase 2

Combined Immunotherapies in Metastatic ER+ Breast Cancer

Recruiting
NCT03079011Phase 3

PAlbociclib and Circulating Tumor DNA for ESR1 Mutation Detection

Completed
NCT05216432Phase 1

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

Recruiting
NCT04423185Phase 2

PLATFORM Study of Precision Medicine for Rare Tumors

Recruiting
NCT06525675

Study to Evaluate the Extended Overall Survival (OS) Data From PARSIFAL Study (The PARSIFAL-LONG Study)

Completed
NCT06331715Phase 4

Bioequivalence Study of Palbociclib 125 mg Capsules of Iclos vs. Ibrance (Palbociclib) Capsules 125 mg

Completed
NCT06307249Phase 1

Precision Therapy for Solid Tumors: Synergistic CDK4/6 Inhibition and Anti-VEGF Targeting LncRNA

Recruiting
NCT03709082Phase 1

Palbociclib in Estrogen Receptor Positive (ER+) Human Epidermal Growth Factor Receptor 2 Positive (HER2+) Metastatic Breast Cancer

Terminated
NCT03936270Phase 2

Palbociclib Plus Letrozole Treatment After Progression to Second Line Chemotherapy for Women With ER/PR-positive Ovarian Cancer

Completed
NCT03447132Phase 3

Fulvestrant Versus Fulvestrant Plus Palbociclib in Operable Breast Cancer Responding to Fulvestrant

Completed
NCT04220476Phase 2

CIMER: Combined Immunotherapies in Metastatic ER+ Breast Cancer

Withdrawn
NCT03123744Phase 2

Histology-Independent Study of Palbociclib in Patients With Advanced Cancer

Withdrawn
NCT01209598Phase 2

PD0332991 (Palbociclib) in Patients With Advanced or Metastatic Liposarcoma

Completed
NCT02059330Phase 1

A Study To Investigate Palbociclib (PD-0332991) Pharmacokinetics In Healthy Subjects Of Japanese Descent Relative To Healthy Non-Asian Subjects, And To Determine If Changes In Palbociclib Dose Result In Proportional Changes In Palbociclib Plasma Exposure In Japanese Subjects

Completed

All 19 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
19