Success Metrics

Clinical Success Rate
85.7%

Based on 6 completed trials

Completion Rate
86%(6/7)
Active Trials
0(0%)
Results Posted
100%(6 trials)
Terminated
1(14%)

Phase Distribution

Ph phase_2
2
29%
Ph phase_1
5
71%

Phase Distribution

5

Early Stage

2

Mid Stage

0

Late Stage

Phase Distribution7 total trials
Phase 1Safety & dosage
5(71.4%)
Phase 2Efficacy & side effects
2(28.6%)

Highest Phase Reached

Phase 2

Trial Status & Enrollment

Completion Rate

85.7%

6 of 7 finished

Non-Completion Rate

14.3%

1 ended early

Currently Active

0

trials recruiting

Total Trials

7

all time

Status Distribution
Completed(6)
Terminated(1)

Detailed Status

Completed6
Terminated1

Development Timeline

Analytics

Development Status

Total Trials
7
Active
0
Success Rate
85.7%
Most Advanced
Phase 2

Trials by Phase

Phase 15 (71.4%)
Phase 22 (28.6%)

Trials by Status

terminated114%
completed686%

Recent Activity

0 active trials
Showing 5 of 7
terminatedphase_1

A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection

NCT02573857
completedphase_1

Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent

NCT02431650
completedphase_2

OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation

NCT01713621
completedphase_1

A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265

NCT02389348
completedphase_1

Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Volunteers

NCT02453581
View all 7 trials

Clinical Trials (7)

Showing 7 of 7 trials
NCT02573857Phase 1

A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection

Terminated
NCT02431650Phase 1

Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent

Completed
NCT01713621Phase 2

OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation

Completed
NCT02389348Phase 1

A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265

Completed
NCT02453581Phase 1

Effectiveness of OZ439 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy Volunteers

Completed
NCT01713608Phase 1

A Dose-escalation Study to Investigate Safety and Toleration of OZ439

Completed
NCT01213966Phase 2

Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection

Completed

All 7 trials loaded

Drug Details

Intervention Type
DRUG
Total Trials
7