Success Metrics

Clinical Success Rate
92.3%

Based on 12 completed trials

Completion Rate
92%(12/13)
Active Trials
8(36%)
Results Posted
42%(5 trials)
Terminated
1(5%)

Phase Distribution

Ph phase_1
9
41%
Ph phase_2
6
27%
Ph phase_4
1
5%
Ph phase_3
4
18%

Phase Distribution

9

Early Stage

6

Mid Stage

5

Late Stage

Phase Distribution20 total trials
Phase 1Safety & dosage
9(45.0%)
Phase 2Efficacy & side effects
6(30.0%)
Phase 3Large-scale testing
4(20.0%)
Phase 4Post-market surveillance
1(5.0%)

Highest Phase Reached

Phase 4

Trial Status & Enrollment

Completion Rate

92.3%

12 of 13 finished

Non-Completion Rate

7.7%

1 ended early

Currently Active

8

trials recruiting

Total Trials

22

all time

Status Distribution
Active(8)
Completed(12)
Terminated(1)
Other(1)

Detailed Status

Completed12
Active, not recruiting6
Recruiting2
Terminated1
Suspended1

Development Timeline

Analytics

Development Status

Total Trials
22
Active
8
Success Rate
92.3%
Most Advanced
Phase 4

Trials by Phase

Phase 19 (45.0%)
Phase 26 (30.0%)
Phase 34 (20.0%)
Phase 41 (5.0%)

Trials by Status

terminated15%
active_not_recruiting627%
recruiting29%
completed1255%
suspended15%

Recent Activity

Clinical Trials (22)

Showing 20 of 22 trialsScroll for more
NCT04803201Phase 2

Testing the Addition of Duvelisib or CC-486 to the Usual Treatment for Peripheral T-Cell Lymphoma

Suspended
NCT04799275Phase 2

Testing CC-486 (Oral Azacitidine) Plus the Standard Drug Therapy in Patients 75 Years or Older With Newly Diagnosed Diffuse Large B Cell Lymphoma

Active Not Recruiting
NCT03593018Phase 3

Efficacy and Safety of Oral Azacitidine Compared to Investigator's Choice Therapy in Patients With Relapsed or Refractory AITL

Completed
NCT05141682Phase 1

Oral Azacitidine for the Treatment of Relapsed or Refractory T-cell Large Granular Lymphocytic Leukemia

Active Not Recruiting
NCT06370000Phase 4

Oral Azacitidine in Transplant-Eligible Patients With Acute Myeloid Leukemia (AML) Suffering From Health-Inequality

Recruiting
NCT05469737Phase 2

A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Participants With International Prognostic Scoring System Revised (IPSS-R) Low- or Intermediate-risk Myelodysplastic Syndrome (MDS)

Active Not Recruiting
NCT06565975

Characteristics and Outcomes of Acute Myeloid Leukemia (AML) Patients Treated With Oral-Azacitidine Maintenance Therapy in France

Completed
NCT05197426Phase 2

A Study to Compare the Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Best Supportive Care as Maintenance Therapy in Japanese Participants With Acute Myeloid Leukemia (AML) in Complete Remission

Active Not Recruiting
NCT01757535Phase 3

Efficacy of Oral Azacitidine Plus Best Supportive Care as Maintenance Therapy in Subjects With Acute Myeloid Leukemia (AML) in Complete Remission

Completed
NCT05162976Phase 1

CC-486 and Nivolumab for the Treatment of Hodgkin Lymphoma Refractory to PD-1 Therapy or Relapsed

Active Not Recruiting
NCT04578600Phase 1

CC-486, Lenalidomide, and Obinutuzumab for the Treatment of Recurrent or Refractory CD20 Positive B-cell Lymphoma

Completed
NCT01566695Phase 3

The Efficacy and Safety of Oral Azacitidine Plus Best Supportive Care Versus Placebo and Best Supportive Care in Subjects With Red Blood Cell (RBC) Transfusion-Dependent Anemia and Thrombocytopenia Due to International Prognostic Scoring System (IPSS) Low Risk Myelodysplastic Syndrome (MDS)

Completed
NCT06073769

A Post-Marketing Surveillance Study to Assess the Safety of Oral Azacitidine Maintenance Therapy in Korean Patients With Acute Myeloid Leukemia

Recruiting
NCT03450343Phase 1

Oral Azacitidine Plus Salvage Chemotherapy in Relapsed/Refractory Diffuse Large B Cell Lymphoma

Completed
NCT02281084Phase 2

Safety and Efficacy Study of CC-486 in Subjects With Myelodysplastic Syndromes

Completed
NCT04173533Phase 3

Randomised Study of Oral Azacitidine vs Placebo Maintenance in AML or MDS Patients After Allo-SCT

Active Not Recruiting
NCT01845805Phase 2

Trial to Improve Outcomes in Patients With Resected Pancreatic Cancer (Azacitidine)

Completed
NCT02343536Phase 1

A Phase 1, Open-label Trial of Oral Azacitidine (CC-486) Plus RCHOP in Subjects With Large B-Cell Lymphoma or Follicular Lymphoma or Transformed Lymphoma

Completed
NCT01571648Phase 1

A Phase 1 Study to Evaluate the Pharmacokinetics and Tolerability of Oral Azacitidine in Japanese Patients With Myelodysplastic Syndromes

Completed
NCT01519011Phase 1

Study to Evaluate Pharmacokinetics, Food Effect, Safety and Efficacy of Oral Azacitidine

Completed

Drug Details

Intervention Type
DRUG
Total Trials
22